Protein Alignment Actn3 and ehbp-1

DIOPT Version :10

• Sequence 1: NP_524801.1
• Gene: Actn3 / 44964
• FlyBaseID: FBgn0015008
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: NP_505468.1
• Gene: ehbp-1 / 179343
• WormBaseID: WBGene00009098
• Length: 901
• Species: Caenorhabditis elegans
• Alignment Length: 536
• Identity: 111/536 - (20%)
• Similarity: 184/536 - (34%)
• Gaps: 171/536 - (31%)

  Fly   120 LRLMLKNEKKK---------QELEI------MGHNLIIMKEKTLVLQARKNQRAAENRLAEKQDR 169
            ||.:.::.||.         |||.:      ...||.:.     .:..|:...:.|.:..|..|.
 Worm     5 LRRLRRSNKKAAKFRFTVTLQELHLYTDEQWKPENLAVS-----FVHRRRKVSSKERKWEECSDA 64

  Fly   170 IKALEECLANCKFQLKNVNEQYQKLKKASNQLIRESNQIRPQKSWSVLV------GRRKGRISTR 228
            .|    ||....       ||:.:.......|.|.::.....|.|:::|      |:||...:
 Worm    65 NK----CLIMWP-------EQFSENIDILTTLYRIASDEYEDKEWTIVVEEVTAKGKRKAIAA-- 116

  Fly   229 TSFVWKSLKLDQSERETLMGLKKRLSEEKEIKLRAKTEMSKIRKAMDELCLGKGELQFGLQNKSE 293
                     :..:.|..::.|....||.| :|||..|...|:...:  :.||...:       ||
 Worm   117 ---------VPLNVRLFILDLPDHKSELK-LKLRPLTPHLKLCSLI--ILLGSSLI-------SE 162

  Fly   294 TDASKDTLVVIDKALSALSQYNTLKFPDCNFQLSR--LMKSLYGSLTTIRDRWI---RKISSAVE 353
            .:|. |..:....|.|.:.:.......|.:...||  ..:....:..|....||   ::|:..:.
 Worm   163 VNAD-DVSITSSAAASFVEKVPVTDEVDASANDSRAAAARQQIDTTATKMMEWIKEEKEIAPPIV 226

  Fly   354 PT---PSCLKSNTPSLPEPPLTVSFSTDLFWDKIYKPCTQSNPVMPNTSLIPVLPKKQPKSLQLT 415
            |.   ||....| |:...|...||...:          ..|.|..|    .|:...:..:|.:.:
 Worm   227 PAHRKPSGENEN-PAKVRPQWRVSAEEE----------KTSQPAAP----APIATNRHSRSSRAS 276

  Fly   416 CE----PSVQYKVASRSS----TTAPVPKYL-------GKTFGDRRLS------------LLRWC 453
            .|    .:::::|.|.|.    |....|.||       |::...|..|            ||.||
 Worm   277 TEEKASTTIEFRVDSNSRHVPVTAIATPYYLQSGTMSRGRSNSPRAPSRDAVPQPIDGETLLSWC 341

  Fly   454 QERVKPYG-IPMYEFSASWISGRALCAIIHSYLPDLI---------------------------- 489
            |.....|. :.:.:|..||.:|.||||::|||.||||
 Worm   342 QRVTNGYSHVKVNDFMKSWNNGLALCAVLHSYRPDLIGDYETLDISNNMSGRISNIQRALDSLTL 406

  Fly   490 ---------DKTYLAKKKPEEVL-------------------AYGIKVAKSIGVSDS----VDLI 522
                     |......:|..|.|                   |...:::::.|:::|    |.:|
 Worm   407 IGITEVPTVDMFLTPDRKQIEFLLQHLRRIFEGFDEGSTPASASDHRISRTFGINESEEKVVAMI 471

  Fly   523 RELRQGRPNLEKIVDF 538
            .|:| .:.:||:.||:
 Worm   472 TEIR-NQKDLEEAVDY 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn3	NP_524801.1	SMC_N	<13..277	CDD:481474	36/177 (20%)
		CH_SF	443..540	CDD:469584	38/169 (22%)
ehbp-1	NP_505468.1	NT-C2	12..140	CDD:463058	30/155 (19%)
		CH_SF	333..437	CDD:469584	25/103 (24%)
		bMERB_dom	742..868	CDD:463467