Protein Alignment Actn3 and smtnl2

DIOPT Version :10

• Sequence 1: NP_524801.1
• Gene: Actn3 / 44964
• FlyBaseID: FBgn0015008
• Length: 553
• Species: Drosophila melanogaster
• Sequence 2: XP_002933584.2
• Gene: smtnl2 / 100494968
• XenbaseID: XB-GENE-5830018
• Length: 444
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 111/512 - (21%)
• Similarity: 196/512 - (38%)
• Gaps: 123/512 - (24%)

  Fly    90 LSVSRFPYQESSCTTTETLVKESPICELNKLRLMLKNEKKKQELEIMGHNLIIMKEKTLVLQARK 154
            |.||.:|  .:.|.:.:..|....:.|   ||..:.|.::..|.::         |..|.|....
 Frog     5 LEVSDWP--SAGCKSEDNAVLHGAMLE---LRSEMNNFRRGVERQL---------EDVLRLAGPL 55

  Fly   155 NQRAAE-----NRLAEKQDRIKALEECLANCKFQLKNVNEQYQKLKKASNQLIRESNQIR---PQ 211
            ::..|:     .||.|:.||:....|.|:    :...::|: ...:.:|:.|:..|.:.:   |:
 Frog    56 SRSVADLQCENRRLREQVDRLSRQVELLS----RAAGLSEE-GPTRFSSHALLSLSGKAQSAVPE 115

  Fly   212 KSWSVLVGRRKGRISTRTSFV---WKSL----KLDQ-SERETLMGLKKRLSEEKEIKL--RAKTE 266
            ....|     :...:|.:|.|   .|||    |:.| |.....:......|...::::  ...|.
 Frog   116 AENDV-----ETACTTASSVVENGHKSLSDKDKVSQDSGTSAPVSTTHSPSPTPDVRMPHMPVTA 175

  Fly   267 MSKIRKAMDELCLGKGELQFGLQNKSETDASKDTLVVIDKALSALSQYNTLKFPDCNFQLSRLMK 331
            ::|:...............:|.:.|:.|:||..|    ..|.||:..:|.        .:.|.|
 Frog   176 VTKVVGEAPPSVTNGSSRHYGQEPKNSTEASPKT----SNAQSAVRTWNA--------SIVRTM- 227

  Fly   332 SLYGSLTTIRDRWIRKISSAVEPTPSCLKSNTPSLPEPPLTVSF-STDLFWDKIYKPCTQSNPVM 395
                           .:||:.|.|.|..|: |.|......|||. |:|.::|  ..|.:.|.|
 Frog   228 ---------------GVSSSSEKTISATKT-TQSYSMTSSTVSSESSDRYFD--VTPKSHSPP-- 272

  Fly   396 PNTSLIPVLPKKQPKSLQLTCEPSVQYKVASRSSTTAPVPKYLGKTF--------GDRRLS---- 448
                  |.:.::..|..:|     |:.:...||:.| .|.|...:.|        |:.::.
 Frog   273 ------PAISRQAEKKREL-----VRSQTLPRSAGT-QVRKAFFEKFDQDSAKGKGESKVKLKRS 325

  Fly   449 --------------LLRWCQERVKPY-GIPMYEFSASWISGRALCAIIHSYLPDLIDKTYLA--- 495
                          ||.||:.:...| .|.:..||:||..|.|.||::||:.|:..|...|.
 Frog   326 QSFGVSSATSIKQILLEWCRSKTIGYKNIELQNFSSSWNDGMAFCALVHSFFPEAFDYDALEPSN 390

  Fly   496 -KKKPEEVLAYGIKVAKSIGVSDSVDLIRELRQGR-PNLEKIVDFVEELQGYLDMYD 550
             |...|:..:...|:|....:.:..|:   |..|| |:...:..:|:.|..:|..::
 Frog   391 HKHNFEQAFSSAEKLANCERLIEVEDM---LMMGRKPDPMCVFTYVQSLYNHLRRFE 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn3	NP_524801.1	SMC_N	<13..277	CDD:481474	40/204 (20%)
		CH_SF	443..540	CDD:469584	29/120 (24%)
smtnl2	XP_002933584.2	PRK12323	<69..224	CDD:481241	34/176 (19%)
		CH_SMTNL2	335..441	CDD:409110	30/108 (28%)