Protein Alignment Eip93F and LCORL

DIOPT Version :9

• Sequence 1: NP_001097865.1
• Gene: Eip93F / 44936
• FlyBaseID: FBgn0264490
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_011512123.1
• Gene: LCORL / 254251
• HGNCID: 30776
• Length: 1875
• Species: Homo sapiens
• Alignment Length: 1363
• Identity: 238/1363 - (17%)
• Similarity: 428/1363 - (31%)
• Gaps: 471/1363 - (34%)

  Fly     2 ADCSYVRCQQERRLIKKKLLKWSTDMLHIVALERVAEECMG---RRQWKHYQD----KLT----- 54
            |.|...||..|||..:::|..|...::|.|..|.:.|...|   ||....::|    :||
Human    22 AQCRSPRCAAERRGFRRELDSWRHRLMHCVGFESILEGLYGPRLRRDLSLFEDCEPEELTDWSMD 86

  Fly    55 --CSHLNIEEQQPIAIAGSEDEPSQYNHSS---KEIS---QSNPN--HCKTENH----------- 98
              ||..|::.:     |.|:..||..:..|   :|:|   |||.:  .|:.||:
Human    87 EKCSFCNLQRE-----AVSDCIPSLDSSQSTPTEELSSQGQSNTDKIECQAENYLNALFRKKDLP 146

  Fly    99 -------------------------------RLEQQHNGS-------QLLEEEDSENNQTSHDSS 125
                                           :.::..|||       :.::...:||:.......
Human   147 QNCDPNIPLVAQELMKKMIRQFAIEYISKSGKTQENRNGSIGPSIVCKSIQMNQAENSLQEEQEG 211

  Fly   126 RTPTPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLVAESAATATSSSTSNSHIHQHD 190
                            |:|               ||||...:...:........||..:.|...:
Human   212 ----------------PLD---------------LTVNRMQEQNTQQGDGVLDLSTKKTSIKSEE 245

  Fly   191 SDSNSSASLPHHISSSSSSNNNSSGNRARHIAAASARATPAAATPANSLELYKLLTQRAAKMTSM 255
            |.          |...||.|:         :|.::..|                   ::.:.|.|
Human   246 SS----------ICDPSSENS---------VAGSTVDA-------------------KSEEATKM 272

  Fly   256 DSMAAQLAQFSLLADFNLINSLASQQQQQ---------QQQQIASAVTPTTS-EVSAAAISPALK 310
            :...:.|.:        ::.||....|||         |:|..||.....|| .||:.:..|.::
Human   273 EKRKSALNK--------VLESLCIHHQQQVLAMLKFLVQEQNAASLCCCNTSCVVSSESQKPLIE 329

  Fly   311 D----------------------TPSPSVDAPL-----DLSS-----------KPSPNSSISGDV 337
            |                      ..||.:: ||     ||..           ||..|..|:...
Human   330 DDLCGLFCSCEYRLAERGCLQNEKQSPGLE-PLPVCIKDLHCLSCQTVTVEHVKPVVNRGIADSY 393

  Fly   338 KSVRACATPTP---SGRRAYSEEDLSRALQDVVANKLDARKSASQHHEQRSILDNRLFKMKHHDQ 399
            .|.|.|:...|   |.:.|:....||:.:.|:.....||.:|.|......|.::...|
Human   394 NSHRCCSGLLPNIHSTKSAFRSPLLSKEVCDLSVTLKDACRSRSPSPPPLSPIETEGF------- 451

  Fly   400 EQDHDGDELED--------SNDDAEAEVDSNASTPVYPAEFARAQLRKLSHLSEHNGSDLGEDVD 456
                  ::|:|        .|:..||.:  |....:.|||.:       |:.|:|....|.....
Human   452 ------EKLKDVISEISALENNKLEANI--NQPPSLTPAEIS-------SNKSDHQDKILKTKKS 501

  Fly   457 RGSPKMGRHPACGNASAN--QGAPPSIPLDANVLLHTLM--LAAGIGAMPKLDETQTV------- 510
            ..|..:..:.: .|::.|  :|       :..|:...||  :...:.::...|.|..|
Human   502 SNSYSLLSNDS-NNSTTNHEKG-------ETAVIFQDLMDRINEKLKSIETTDMTSLVKLSSSDY 558

  Fly   511 --------GDFIKGLLVANSGGIMNEGLLNLLSASQ---ENS-----------------NGNASL 547
                    ||||..||  ::....:...:.|||...   ||.                 |.:.|.
Human   559 NTYNDLKLGDFITSLL--HNAKASDYSFMELLSQHDKKVENKIIQTRFRKRQETLFAMRNSSDSP 621

  Fly   548 LLQQQQHQ---------------QHHQQHHQQQQQQQHVAA------YRHRLPKSETPE------ 585
            :.::|..|               ::.::..::..|...:::      |..:.|..:..:
Human   622 MFRRQSLQIKRELASLDENFTRKKYTEKSSRKLTQNNEISSSDKGEFYHDQGPSLQNSKRLQGKN 686

  Fly   586 -TNSSLDPNDASEDPILKIP---------------SFKVSGPASSSSLSPGG--------LVGGH 626
             ..:|..||.|.:.  |::|               |||.:.|...|...|..        |....
Human   687 HAETSFSPNYALQS--LQLPLHSSETNLSFNEFSESFKTTSPEKMSIRKPQEKSADGKQFLQNDR 749

  Fly   627 HHP-LNNNNSLSISNNSNHSSNSHRNGSNRSPHSASPMLAAAVAQGGYS--AGNSLLTSSSSSIQ 688
            .:| |.|..:|..::.|...|.:.||               .|..|.||  ..|:.:...|...:
Human   750 KNPKLGNTQTLLRNDVSGLLSRTKRN---------------IVPPGWYSVYVTNNYVFKKSPKAK 799

  Fly   689 KMMASNIQRQINEQSGQESLRNGNVSDCSSNNGGSSSLGYKKPSISVAKIIGGTD--TSRFGASP 751
            |:..|..:....:....||..|.:::..:.|:.....:...:.:||:||......  :..:.||.
Human   800 KVSESTTKNDPVKNIHIESSHNIDLNKIAMNSNLQVVVKRLEDTISIAKKSWNNQPLSEGYKASK 864

  Fly   752 NLL---SQQHHSAHHLT----HQQQQQQLSAQEALGKGT------RP----KRGKYRNYDRDSL- 798
            .|:   .:..|:..::|    ....::|..::..:..|.      .|    ...:..|..:.|:
Human   865 KLIEIDGKDQHADRNMTLTLNRMTCKEQSLSKSVVASGNIINSHCMPTVDLNNKRLENLKKSSIL 929

  Fly   799 --------VEAVKAVQRGE--------------MSVHRAGSYYGVPHSTLEYKVKERHLMRPRKR 841
                    ||.|.|...|.              |.:....|..||.::.........:::.|.::
Human   930 DMGRLISSVENVPAKYEGTESSSVSNYSSPIKLMFLSEVKSSEGVKYTLTSVGTSHSNVVLPSEK 994

  Fly   842 EPKPQPDLVGLTGPANKLQLDKLKAGP---HGGSKLSNALKNQNNQAAAAAAAAAAA-------- 895
                 |....:|....:...|...|..   |.....::..:.:.|:.:.|...|.::
Human   995 -----PTTHHVTEEKTETNEDISNANSENYHSSHYDTDTFQRELNKFSHAKETAGSSTMFIGDIN 1054

  Fly   896 -----------AAAATPNGLKLPLFEAGPQALSFQPNMFWPQT--NATNAYG------LDFNRIT 941
                       :::||.     |.|:..|.    :|....||.  ......|      :|...||
Human  1055 SDKPQEEPKDNSSSATD-----PSFKRKPG----RPKKIGPQVVKQIKRPIGRPPKPKIDQTNIT 1110

  Fly   942 EAMRNPQASNHHGLMKSAQDMVENVYDGIIRKTLQASEGNGSAAGNGSNGSNGNGHGHGHGHGHA 1006
            .....|.::..    ||.:.::..|.:||.:|::..:...|.:.....:.|.|.
Human  1111 VCQNEPFSAGR----KSPECLISEVKEGIYKKSITVTVIYGRSRRTKRHVSEGR----------- 1160

  Fly  1007 LLDQLLVKKTPLPFTNHRNNDYAATCSSASGESVKRSGSPMGNYADIKRERLSADSGGSSDEE 1069
                  |..:.|...|:...|:....:|.  .::......:|       ||:||.:..:::.|
Human  1161 ------VNISNLMSLNNNAGDFPTEYNSP--RNISEDKIDLG-------ERISAVASLTTESE 1208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip93F	NP_001097865.1	HTH_psq	794..839	CDD:283007	10/67 (15%)
LCORL	XP_011512123.1	DUF4553	1416..1866	CDD:291749

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11487
eggNOG	1	0.900	-	-		E1_KOG4565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002368
OrthoInspector	1	1.000	-	-		otm41978
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21545
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3313
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.990