Protein Alignment Eip93F and Lcor

DIOPT Version :9

• Sequence 1: NP_001097865.1
• Gene: Eip93F / 44936
• FlyBaseID: FBgn0264490
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001357696.1
• Gene: Lcor / 212391
• MGIID: 2443930
• Length: 1696
• Species: Mus musculus
• Alignment Length: 1142
• Identity: 216/1142 - (18%)
• Similarity: 360/1142 - (31%)
• Gaps: 410/1142 - (35%)

  Fly    30 IVALERVAEECMGRRQWKHYQDKLTCSHLNIEEQQPIAIAGSEDEPSQYNHSSKEISQ------- 87
            :.|:|.|||                    |.||       |.....||.| |.|.:|:
Mouse   317 LAAVEEVAE--------------------NTEE-------GGSCIVSQRN-SFKALSEETWDSGF 353

  Fly    88 -SNPNHCKTENHRLEQQHNGS--QLLE--EEDSENNQTSH---------------------DSSR 126
             .|.:....:.:.|:.....|  |.||  |:|:...|.:|                     |.||
Mouse   354 MGNSSSTADKENALQSSSKSSFHQDLETDEQDARPKQENHLHSLGRNKVGFQTYPRDKGHFDHSR 418

  Fly   127 TPTPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLVAESAATATSSS-TSNSHIHQHD 190
                |....|||.|         ..:...||     ::|.|:::.|..||..|. .|...|:.:|
Mouse   419 ----GGWLAPSPTP---------TVHRASNG-----HSQTKMMSASIKTARKSKRASGLRINDYD 465

  Fly   191 SDSN----SSASLPHH-------ISSSSSSNNNSSG--------------NRARHI-----AAAS 225
            :..:    |......|       :||..::..::.|              ..||::     .:.|
Mouse   466 NQCDVVYISQPITECHFENQRSILSSRKTARKSTRGYFFNGDCCELPTVRTLARNLCSQDKGSCS 530

  Fly   226 ARATPAAATPANSLELYKLLTQRAAKMT---SMDSMAAQLAQFSLLADFNLINSLASQQQQQQQQ 287
            ..|:.|..||..:      ||...:|.|   .:.::.|||....:           .......|.
Mouse   531 QVASEAVMTPKQT------LTVPTSKHTVGVQLPTVGAQLPTTDV-----------QPPTAGTQL 578

  Fly   288 QIASAVTPT------TSEVSAAAISPAL--KDTPSPSVDAPLDLSSKPSPNSSI---SGDVKSVR 341
            ..|...:||      |::|.:..:...|  .|...|:||..|..:....|...:   :.||:
Mouse   579 PTADVQSPTVGAQLPTADVQSPTVGAQLPTADVQPPTVDVQLPTADVQPPTGGVQLPTADVQ--- 640

  Fly   342 ACATPTPSGRRAYSEEDLSRA-----LQDVVANKLDARKSASQHH-----EQRSILDNRLFKMKH 396
               .||...:....:..||..     ..||....:.|:..|:...     .|.|.:|.:|..:
Mouse   641 ---PPTVGAQLPRVDVQLSSVGTQLPTADVQPPTVGAQLPAADVQLPTVDVQISTVDTQLSTV-- 700

  Fly   397 HDQEQDHDGDE-LEDSNDDAEAEVDSNASTPVYPAEFARAQL----RKLSHLSEHNGSD----LG 452
                    |:: |||..||...|               |..|    ...|...:|..::    |.
Mouse   701 --------GEQPLEDICDDPRKE---------------RTSLEGGDEDTSSAKKHQEAEVCLSLR 742

  Fly   453 EDVDRGSPKMGR----HPACGNASANQGAPPSIPLDANVLLHTLMLAAGIGAMPKLDETQTVGDF 513
            |.....||:.|.    .|||                   ||.||:....:..:|
Mouse   743 EQDPSSSPRPGETTTSSPAC-------------------LLPTLLPNDNMSEVP----------- 777

  Fly   514 IKGLLVANSGGIMNEGLLNLLSASQENSNGNASLLLQQQQHQQHHQQHHQQQQQQQHVAAYRHRL 578
             :|.:|.                    |....|:|..|:|.|....|...::.|.|..    |.:
Mouse   778 -EGSIVV--------------------SPPTESVLSFQEQDQPPASQLGPEEMQAQEC----HLV 817

  Fly   579 PKS-ETPETNSSLDPNDASEDPILK---IPSFKVSGPASSSSLSPGGLVGGHHHPLNNNNSLSIS 639
            |.: .||.|:     .:.|||.:.:   .|...:...:|..|...|..|.     |:....|.:|
Mouse   818 PTAGSTPFTS-----REDSEDLLCRPQSSPKTSIREESSPCSEDEGSTVA-----LDPPLGLELS 872

  Fly   640 NNSNHSSNSHRN----GSNRSPHSASPMLAAAVA---------QGGYSAGNSLLTSSSSSIQKMM 691
            .:...:|.....    |.......:.|:|.:::.         :|..::|...|.:..:. .|..
Mouse   873 EHDQSTSTEAETRDIPGETLLLDDSLPLLESSIVTDENPSEMEEGEATSGTGHLEAHDND-TKYS 936

  Fly   692 ASNIQRQINEQSGQES-----------------LRNGNVSDCSSNNGGSSSLGY----------- 728
            |.|...:.|..|.:|:                 ||: .:.|.||::....|.|.
Mouse   937 AENDPSEPNSDSPEENVDKKKKARKFPEASDRCLRS-QLGDPSSSDRYPGSQGLDSSAACSEIKV 1000

  Fly   729 -KKPSISVAKIIGGTDTSRFGASPNLLSQQHHS----------AHHLTHQQQQQQLSAQEALGKG 782
             |.|::..:|..|  |:.|..:...::...|..          :.|.:.::.:|:   .|.:|..
Mouse  1001 SKNPAVKHSKREG--DSGRVTSEGPVIDSIHPDNLEDPEDSGVSEHSSDEETKQE---TEGVGVI 1060

  Fly   783 TRPKRGKYRNYDRDSLVEAVKAVQRGEMSVHRAGSY---------YGVPHSTLE----YKVKER- 833
            ||               :.||.:...|:.....|:|         ..:|...||    .|:.||
Mouse  1061 TR---------------QTVKNMLAKEIKREEGGTYPNSDPATVGQPLPGDNLETHVWSKIDERD 1110

  Fly   834 -HLMR---PRKREPKPQPDLVGLTGPANKLQLDKLKAGPHGGSKLSNALKNQNNQAAA------- 887
             |:..   |.||:|                  :::|..|       ..|..|:.:|||
Mouse  1111 AHVPSESIPCKRDP------------------EQVKENP-------GHLAIQDTEAAAMSEVDPE 1150

  Fly   888 ---------AAAAAAAAAAAATPNGLKLPLFEAGPQALSFQPNMFWPQT-NATNAY---GLDFNR 939
                     .|..:::..:|:..:|..      ||.....:|......| |..:|:   .||..:
Mouse  1151 DTHHKDDAGLAPCSSSGISASHSDGAD------GPPKSVTRPKRLPSSTYNLRHAHCSNALDTAK 1209

  Fly   940 ITEAMRNPQ---ASNHHGLMKSAQDMVENVYDGIIRK 973
            :|...:..|   |:...|..:||:.:.|...|.::.:
Mouse  1210 MTSEKQGTQVNPAAKEGGASESAEPLDEEDEDSVVEE 1246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip93F	NP_001097865.1	HTH_psq	794..839	CDD:283007	12/62 (19%)
Lcor	NP_001357696.1	Interaction with nuclear receptors. /evidence=ECO:0000250	53..57
		Herpes_BLLF1	<558..823	CDD:282904	67/361 (19%)
		PTZ00441	<726..959	CDD:240420	55/298 (18%)
		DUF4553	1247..1694	CDD:317502	216/1142 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11390
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002368
OrthoInspector	1	1.000	-	-		otm44027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21545
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3313
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.130