Protein Alignment Eip93F and Lcorl

DIOPT Version :9

• Sequence 1: NP_001097865.1
• Gene: Eip93F / 44936
• FlyBaseID: FBgn0264490
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: XP_006503881.1
• Gene: Lcorl / 209707
• MGIID: 2651932
• Length: 1851
• Species: Mus musculus
• Alignment Length: 1400
• Identity: 251/1400 - (17%)
• Similarity: 406/1400 - (28%)
• Gaps: 573/1400 - (40%)

  Fly     2 ADCSYVRCQQERRLIKKKLLKWSTDMLHIVALERVAEECMG---RRQWKHYQDKLTCSHLNIEEQ 63
            |.|...||..|||..:::|..|...::|.|..|.:.|...|   ||....::|
Mouse    21 AQCRSPRCAAERRGFRRELDSWRHRLMHCVGFESILEGLYGPRLRRDLSLFED------------ 73

  Fly    64 QPIAIAGSEDEPSQYNHSSKEISQSNPNHCKTENHRLEQQHNGSQLLEEEDSENNQTSHDSSRTP 128
                                         |:
Mouse    74 -----------------------------CE---------------------------------- 75

  Fly   129 TPGATSTPSPPPEPIDWRPSAKCNFCVNGRLLTVNAQGKLV---------AESAATATSSSTSNS 184
                      |.|..||....||:||        |.|.:.|         ::|..|...||...|
Mouse    76 ----------PEELTDWSMDEKCSFC--------NLQREAVSDCIPSLDSSQSTPTEELSSQGQS 122

  Fly   185 H---------------IHQHDSDSNSSASLP----------------HHISSSSSSNNNSSGNRA 218
            |               ..:.|...|...::|                .:||.|.....|.:|:
Mouse   123 HTDKIECQAESYLNALFRKKDLPQNCDPNIPLVAQELMKKMIRQFAIEYISKSGKIQENRNGS-- 185

  Fly   219 RHIAAASARATPAAATPANSLELYKLLTQRAAKMTSMDSMAAQLAQFSLLADFNLINSLASQQQQ 283
              |.|:                    |..::.:|...|                  |.|    |.
Mouse   186 --IGAS--------------------LVCKSIQMNQAD------------------NCL----QD 206

  Fly   284 QQQQQIASAVTPTTSEVSAAAISPALKDTPSPSVDAPLDLSSK----PSPNSSISGDVKSVRACA 344
            :|:..:...||.|..:.:...             |..||||:|    .|..|||| |..|..|.|
Mouse   207 EQEGPLDLTVTRTQEQTAQQG-------------DGVLDLSTKKTSIKSEESSIS-DPSSENAVA 257

  Fly   345 TPTPSGRRAYSEEDLSRALQDVVANKLDARKSASQ--------HHEQRSILDNRLFKMKHHDQEQ 401
            ..|..   |.|||          |.|::..|||..        ||.|:.     |..:|...|||
Mouse   258 GSTVD---AKSEE----------ATKMEKGKSALSKVLESLCIHHHQQV-----LAMLKFLVQEQ 304

  Fly   402 DHDGDELEDSNDDAEAEVDSNASTPVYPAEFARAQLRKLSHLSEHNGSDLGEDVDRGSPKMGRHP 466
                        :|.:....|:|..                :|..:...|.||        |.|.
Mouse   305 ------------NAASLCCCNSSCA----------------MSSESQKPLLED--------GFHG 333

  Fly   467 ---ACGNASANQG-------APPSIPLDANVLLHTLMLAAGIGAMPKLDETQTVGDFIKGLLVAN 521
               :|....|.:|       :|..:||.  |.:..:...:          .|||       .|.:
Mouse   334 LFCSCEYRLAERGCLQNERQSPGLVPLP--VCIKEIQCLS----------CQTV-------TVEH 379

  Fly   522 SGGIMNEGLLNLLSASQENSNGNASLLLQQQQHQQHHQQHHQQQQQQQHVAAYRHRLPKS-ETPE 585
            ...:||.|:        |||:             ..|:....|..:.|......|..|.| |..:
Mouse   380 IKTVMNRGI--------ENSS-------------NPHRCCCGQLAKTQSTKPACHSPPLSREVCD 423

  Fly   586 TNSSLDPNDASEDPILKIPSFKVSGPASSSSLSPGGL------------VGGHHHPLNNNNSLSI 638
            .:.:|.....|..|          .|...|.:..|||            |        .||.|..
Mouse   424 LSVTLQNTCRSRSP----------SPPPLSPVETGGLEKWKDIVSELSAV--------ENNKLEA 470

  Fly   639 SNNS--------------NHSSNSHRNGSNRSPHSASPMLAAAVAQGGYSAGNSLLTSSSSSIQK 689
            |.|.              .|.|..|:  :.:|.::.|.:|..:   |.|:|.:      ......
Mouse   471 SINQPPSLTPAEISTHKCGHDSKLHK--TKKSGNTDSVLLGTS---GSYTANH------EKGETA 524

  Fly   690 MMASNIQRQINEQSGQESLRNGNVS--------DCSSNNGGSSSLGYKKPSISVAKIIGGTDTSR 746
            ::..::..:|||:  .:|:...::|        ||.|:|      .:|         :|...||
Mouse   525 VIFQDLMDRINEK--LKSIETTDISNLIKLSSTDCDSDN------DFK---------LGDLITS- 571

  Fly   747 FGASPNLLSQQHHSAHHLTHQQQQQQLSAQEALGKGTRPKRGKYRNYDRDSLVEAVKAVQRGEMS 811
                             |.|.......|..|.|.:..:....|.       :....:..|:..::
Mouse   572 -----------------LLHSATASDYSFMELLSQHDKKVENKI-------IQTRFRKRQQTLLA 612

  Fly   812 VHRAGSYYGVPHSTLEYKVK----ERHLMRPRKREPKPQPDLVGLTGPANKLQLDKLKAGP-HGG 871
            :|.:.....:...:|:.|.:    :.:.:|.|..|...:.    |:.....|.::|.:..| ...
Mouse   613 IHNSPDSPVIRRQSLQIKRELASFDENFLRRRYSEKNSRK----LSYSDKMLSVNKEEFQPCQEP 673

  Fly   872 SKLSNALKNQNNQAAAA---AAAAAAAAAAATPNGLKLPLFEAGPQALSFQ-------------- 919
            .|:|.:.:|:|::....   .|.:......:....|.|..|....:|.||:
Mouse   674 LKISKSFQNENHEETFTPNEVAPSIQVPLGSLETNLALDQFSENFKATSFEKMSQRKSQERSTAE 738

  Fly   920 ----------------PNMF------------------WPQTNATN----------------AYG 934
                            |.:.                  |.....||                |:.
Mouse   739 KPTVQSSRENTKLENTPTLLRTDAPLLSRTKRNIVPPGWYSIYVTNDSVSKKFLEGKRVSGSAHR 803

  Fly   935 LDFNRITEAMRNPQASNHHGLMKSAQDMVENVYDGI------------------IRKTLQASEGN 981
            .|....||:.:|... |...:..|.|.:||.:.|.|                  .:|.::|.:.:
Mouse   804 KDLGDPTESFQNIDL-NKIAMNSSLQVVVERLEDTINMAQRSWTSQELSEGCKASKKLIEAGDKD 867

  Fly   982 GSAAGN--------GSNGSNGNGHGHGHGHGHAL--------LDQLLVKKTPLPFTNHRNNDYAA 1030
            .:|..:        .:.|.:.:.........|.:        ||.|  |.:|:         ...
Mouse   868 QNAGRDLTLSRMACKNQGLSKSVFASSSKRSHDMSVMDLNKTLDNL--KTSPI---------LEK 921

  Fly  1031 TCSSASGESV--KRSG--SPMGNY-ADIKRERLSADSGGSSDEEHSASHI--NNNNSDLAHNKNK 1088
            ..|:||.||:  |..|  |.:.|| :.||...|| :...|...:::.:.:  :.:|:|...:|:|
Mouse   922 GSSTASVESLPTKCEGIESSVSNYFSPIKLMFLS-EIKSSEGVKYTLTSVSTSQSNADFDSHKHK 985

  Fly  1089 SGGGGGGGGNGQTNGNGRSSRMTSRDDSETDASSLKSGESGGQQNHKMMDLNGGSSSSSHIKCES 1153
                     |.|..|.   .|.|:.|...|:.....|       ||.:.:|   .|..:...|..
Mouse   986 ---------NHQITGR---KRETTEDTPNTNLEDYSS-------NHHVSNL---QSELNQFNCVL 1028

  Fly  1154 EAATGHHSPGHHTTSILHEKLAQIKAEQVDQADQL 1188
            ||..   |....|.::.::|..:...|:.:.|..|
Mouse  1029 EATP---SSAEFTDNLNNDKPQEDPKEKSNGAVDL 1060

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eip93F	NP_001097865.1	HTH_psq	794..839	CDD:283007	5/48 (10%)
Lcorl	XP_006503881.1	DUF4553	1402..1846	CDD:373549

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11390
eggNOG	1	0.900	-	-		E1_KOG4565
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002368
OrthoInspector	1	1.000	-	-		otm44027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR21545
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3313
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.990