Protein Alignment Hsp70Ba and LHS1

DIOPT Version :9

• Sequence 1: NP_731716.1
• Gene: Hsp70Ba / 44921
• FlyBaseID: FBgn0013277
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_012850.1
• Gene: LHS1 / 853789
• SGDID: S000001556
• Length: 881
• Species: Saccharomyces cerevisiae
• Alignment Length: 672
• Identity: 159/672 - (23%)
• Similarity: 299/672 - (44%)
• Gaps: 105/672 - (15%)

  Fly     4 IGIDLG-TTYSCVGVYQHGKVEIIANDQGNRTTPSYVAF-----------TDSERLIGDPAKNQV 56
            :|:|.| .....:.|.....:|::...:..|...|.::.           ...||:.|....:..
Yeast    23 LGVDYGQQNIKAIVVSPQAPLELVLTPEAKRKEISGLSIKRLPGYGKDDPNGIERIYGSAVGSLA 87

  Fly    57 AMNPRNTVFDAKRLIGRKYDDPKIAE--DMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSM 119
            ...|:||:...|.|:|:..:|.....  ..:|...::||..   :..:.:..::..:..||:.:|
Yeast    88 TRFPQNTLLHLKPLLGKSLEDETTVTLYSKQHPGLEMVSTN---RSTIAFLVDNVEYPLEELVAM 149

  Fly   120 VLTKMKETAEAYLGES-------ITDAVITVPAYFNDSQRQATKDAGHI-AGLNVLRIINEPTAA 176
            .:.::...|.:.|.:.       :.....|:|.:|:..||:|..||..| .|:....:::|..:.
Yeast   150 NVQEIANRANSLLKDRDARTEDFVNKMSFTIPDFFDQHQRKALLDASSITTGIEETYLVSEGMSV 214

  Fly   177 ALAYGLDKNL--KGE-RNVLIFDLGGGTFDVSILTI------DEGSLFEVRSTAGDTHLGGEDF- 231
            |:.:.|.:..  .|| ::.:::|:|.|:...|:.:|      .:....|......:.||||..|
Yeast   215 AVNFVLKQRQFPPGEQQHYIVYDMGSGSIKASMFSILQPEDTTQPVTIEFEGYGYNPHLGGAKFT 279

  Fly   232 -------DNR-LVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEG 288
                   :|: |.||.|..     ..:|.:||:||.::..|||:||..||:::||:|.|::|...
Yeast   280 MDIGSLIENKFLETHPAIR-----TDELHANPKALAKINQAAEKAKLILSANSEASINIESLIND 339

  Fly   289 QDFYTKVSRARFEELCADLFRNTLQPVEKALNDA--KMDKG------QIHDIVLVGGSTRIPKVQ 345
            .||.|.::|..|||..||    :|..:.|.:|||  |...|      :|:.::|.|||:|||.||
Yeast   340 IDFRTSITRQEFEEFIAD----SLLDIVKPINDAVTKQFGGYGTNLPEINGVILAGGSSRIPIVQ 400

  Fly   346 SLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAG-GVMT 409
            ..|.:....:.:..::|.||:...|..::...||  .|.|.:.:.:||.:..:...:.:. ..:.
Yeast   401 DQLIKLVSEEKVLRNVNADESAVNGVVMRGIKLS--NSFKTKPLNVVDRSVNTYSFKLSNESELY 463

  Fly   410 KLIERNCRIPCKQTKTFSTYSDNQP-GVSIQVYEGER---AMTKDNNALGTFDLSGIPPAPRGVP 470
            .:..|....|.| |...:..:|:.| ..:|.::|..:   .:|.::.|:.....|  .....||
Yeast   464 DVFTRGSAYPNK-TSILTNTTDSIPNNFTIDLFENGKLFETITVNSGAIKNSYSS--DKCSSGV- 524

  Fly   471 QIEVTFDLDANGILNVS------AKEMSTGKAKNITIKNDKGRLS----QAEIDRM-------VN 518
            ...:||||.::.:.::.      ..|...|.:|.  |||...||:    ..||.|:       ::
Yeast   525 AYNITFDLSSDRLFSIQEVNCICQSENDIGNSKQ--IKNKGSRLAFTSEDVEIKRLSPSERSRLH 587

  Fly   519 EAEKYADEDEKHR-QRITSRNALESYVYNVKQSVEQAPAGKLDEADKN---SVLDKCNETIR--- 576
            |..|..|:.:|.| |...:.|.|||.:|:.:..:..      ||..:|   |.:::.:|.::
Yeast   588 EHIKLLDKQDKERFQFQENLNVLESNLYDARNLLMD------DEVMQNGPKSQVEELSEMVKVYL 646

  Fly   577 -WL-DSNTTAEKEEFDHKMEEL 596
             || |::...:.|:...::.|:
Yeast   647 DWLEDASFDTDPEDIVSRIREI 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ba	NP_731716.1	PTZ00009	2..641	CDD:240227	159/672 (24%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	104/422 (25%)
LHS1	NP_012850.1	HYOU1-like_NBD	23..430	CDD:212672	104/418 (25%)
		Smc	<581..737	CDD:224117	21/94 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900