Protein Alignment Hsp70Ba and hspa5

DIOPT Version :10

• Sequence 1: NP_731716.1
• Gene: Hsp70Ba / 44921
• FlyBaseID: FBgn0013277
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_998223.1
• Gene: hspa5 / 378848
• ZFINID: ZDB-GENE-031001-11
• Length: 650
• Species: Danio rerio
• Alignment Length: 619
• Identity: 380/619 - (61%)
• Similarity: 486/619 - (78%)
• Gaps: 12/619 - (1%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAF-TDSERLIGDPAKNQVAMNPRNTVFDA 67
            |||||||||||||||::|:|||||||||||.||||||| |:.||||||.||||:..||.||||||
Zfish    29 IGIDLGTTYSCVGVYKNGRVEIIANDQGNRITPSYVAFTTEGERLIGDAAKNQLTSNPENTVFDA 93

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEY-KGESKRFAPEEISSMVLTKMKETAEAY 131
            ||||||.:.|..:.:|:|::||||:....||.|.::. .|:.|.|||||||:|||||||||||||
Zfish    94 KRLIGRTWGDSSVQQDIKYFPFKVIEKKNKPHIQLDIGSGQMKTFAPEEISAMVLTKMKETAEAY 158

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||:.:|.||:||||||||:|||||||||.||||||:||||||||||:||||||. .||:|:|:||
Zfish   159 LGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKR-DGEKNILVFD 222

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||||||:||||.| :|||.:|.|||||||||||.|::.|..:.:|:|..||:|.:.||:::|
Zfish   223 LGGGTFDVSLLTIDNG-VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKL 286

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |...|:|||.||:..:|.|||::.|||:||...::||:||||..||||:|::||:|.|.|:...|
Zfish   287 RREVEKAKRALSAQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDPKK 351

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            ..|.:||||||||||||:|.|::|||:||..:..|||||||||||||||.:|||::  :..|::|
Zfish   352 PDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGEE--ETGDLVL 414

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.||:|||||.||||||||.||..:|.|:::.|||.|||||.|:|:||||||.:||||:.|||
Zfish   415 LDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGT 479

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |||:||||||||||||||||::|.||||.|:|::..||....|||.||:.||:..:|:|||||||
Zfish   480 FDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEDIERMVNEAE 544

  Fly   522 KYADEDEKHRQRITSRNALESYVYNVKQSV--EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTA 584
            ::||||:|.::||.|||.||||.|::|..:  ::...|||...||.::.....|.|.||:::..|
Zfish   545 RFADEDKKLKERIDSRNELESYAYSLKNQIGDKEKLGGKLSSEDKEAIEKAVEEKIEWLEAHQDA 609

  Fly   585 EKEEFDHKMEELARHCSPIMTKMHQQGAGAAGGP 618
            :.|||..|.:||.....||::|::    |:||||
Zfish   610 DLEEFQAKKKELEEVVQPIVSKLY----GSAGGP 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ba	NP_731716.1	PTZ00009	2..641	CDD:240227	380/619 (61%)
hspa5	NP_998223.1	PTZ00009	29..641	CDD:240227	380/619 (61%)