Protein Alignment Hsp70Ba and Hsc70-5

DIOPT Version :10

• Sequence 1: NP_731716.1
• Gene: Hsp70Ba / 44921
• FlyBaseID: FBgn0013277
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_523741.2
• Gene: Hsc70-5 / 36583
• FlyBaseID: FBgn0001220
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 648
• Identity: 316/648 - (48%)
• Similarity: 427/648 - (65%)
• Gaps: 48/648 - (7%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67
            ||||||||.||:.|.:..:.::|.|.:|.|||||:|||| |.|||:|.|||.|...|..||.:..
  Fly    55 IGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYAT 119

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVV-SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            ||||||::|||::.:|:.:..:||| :..|...:.   ..:.|.::|.:|.:.:|.|||||||||
  Fly   120 KRLIGRRFDDPEVKKDITNLSYKVVKASNGDAWVS---STDGKVYSPSQIGAFILMKMKETAEAY 181

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            |...:.:||:||||||||||||||||||.||||||||:||||||||||||:||.  .::.:.::|
  Fly   182 LNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT--EDKIIAVYD 244

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRL 261
            |||||||:|||.|.:| :|||:||.|||.||||||||.:|..|..|||:....|:|.:..|::||
  Fly   245 LGGGTFDISILEIQKG-VFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRL 308

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEG----QDFYTKVSRARFEELCADLFRNTLQPVEKALNDA 322
            :.|||:||..||||.:..|.:..|...    |....|::|::.|.|..||.:.|:||.:|||:||
  Fly   309 KEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDA 373

  Fly   323 KMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQ 387
            ::.|.:|.:::||||.||:|||||.:||.| |:..:.|:|||||||.|||||..:|:||    :.
  Fly   374 EVSKSEIGEVLLVGGMTRMPKVQSTVQELF-GRQPSRSVNPDEAVAVGAAVQGGVLAGD----VT 433

  Fly   388 DVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNN 452
            ||||:||.||||||||.|||.|:||.||..||.|:::.|||.||.|..|.|:|::|||.|..||.
  Fly   434 DVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNK 498

  Fly   453 ALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMV 517
            .||:|.|.||||||||||||||.||:|||||::||||:..|||.:.|.|:: .|.||:.||:.|:
  Fly   499 LLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQS-SGGLSKDEIENMI 562

  Fly   518 NEAEKYADEDEKHRQRITSRNALESYVYNVKQSVE----QAPAGKLDEADKNSVLDKCNETIRWL 578
            .:||:||..|::.|:.|...|..||.|::.:..:|    |.||   :|.:|   |.|....:|.|
  Fly   563 KKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPA---EECEK---LKKEIADLRTL 621

  Fly   579 DSNTTAEKEEFDHKMEELARHCSPI--------------MTKMHQQGAGAAGGPGANCGQQAG 627
                .|.||..|  :||:.:..|.:              |:...:..|||.....::....:|
  Fly   622 ----LANKETAD--LEEVRKATSSLQQSSLKLFELAYKKMSAERESNAGAGSSDSSSSSDTSG 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ba	NP_731716.1	PTZ00009	2..641	CDD:240227	316/648 (49%)
Hsc70-5	NP_523741.2	dnaK	51..666	CDD:234715	314/634 (50%)