Protein Alignment Hsp70Ba and hspa4a

DIOPT Version :9

• Sequence 1: NP_731716.1
• Gene: Hsp70Ba / 44921
• FlyBaseID: FBgn0013277
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_999881.1
• Gene: hspa4a / 335865
• ZFINID: ZDB-GENE-040426-2832
• Length: 833
• Species: Danio rerio
• Alignment Length: 706
• Identity: 210/706 - (29%)
• Similarity: 340/706 - (48%)
• Gaps: 117/706 - (16%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..:|.|:|.....|.|.:.|.:|.:||:..:|.|||:|:|....|.||..||:||..|.:|||.
Zfish     1 MSVVGFDVGFQSCYVAVARAGGIETVANEYSDRCTPSFVSFGPRNRSIGAAAKSQVVTNCKNTVQ 65

  Fly    66 DAKRLIGRKYDDP-------KIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTK 123
            ..||..||.:.||       .:..|:...|      .|...|.|.|..|.|.|..|::::|:|||
Zfish    66 GFKRFHGRAFSDPYVETTQSSLVYDLAQMP------NGTTGIKVMYMEEEKLFGIEQVTAMLLTK 124

  Fly   124 MKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--- 185
            :|||||:.|.:.:.|.||:||:||.|::|::..||..|||||.||::|:.||.|||||:.|.
Zfish   125 LKETAESALKKPVADCVISVPSYFTDAERRSVMDAAQIAGLNCLRLMNDTTAVALAYGIYKQDLP 189

  Fly   186 --LKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYK 248
              .:..|.|:..|:|...:.||....::|.| :|..:|.|..|||:|||..||.|..|||.:|||
Zfish   190 APEEKPRTVVFVDVGHAGYQVSACAFNKGKL-KVLGSAFDPELGGKDFDEVLVKHFCEEFAQKYK 253

  Fly   249 KDLRSNPRALRRLRTAAERAKRTLS-SSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTL 312
            .|:||.||||.||....|:.|:.:| :|::..:.|:......|..:|::||:||||||.|.....
Zfish   254 LDVRSKPRALVRLYQECEKLKKLMSANSSDLPLNIECFMNDIDVSSKLNRAKFEELCAGLLAKVE 318

  Fly   313 QPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAI 377
            .|::..:...::.|..|:.:.::||::|||.::..:.:|| ||.|:.::|.|||||.|.|:|.||
Zfish   319 APLQSIMEQTRLKKEDIYAVEIIGGASRIPAIKERISKFF-GKELSTTLNLDEAVARGCALQCAI 382

  Fly   378 LSGDQSGKIQDVLLVDVAPLSLGIETAG----GVMTKLIERNCRI-PCKQTKTFS---TYSDNQP 434
            ||  .:.|:::..:.||.|..:.::...    ||      .:|.: |......||   |:...:|
Zfish   383 LS--PAFKVREFSITDVVPYPISLKWTSAADEGV------SDCEVFPKNHAAPFSKVLTFYRKEP 439

  Fly   435 GVSIQVYEGERAMTKDNNALGTFDLSGIPPAPRG-VPQIEVTFDLDANGILNVSA---------- 488
            ......|...:|:...:..:|.|.:..:.|...| ..:::|...::.:|:.:||:
Zfish   440 FTLEAYYNNPKALPYPDPTIGQFTIHKVVPQASGESSKVKVKVRVNVHGVFSVSSASLVELLKPG 504

  Fly   489 -------------------------------------------KEMSTGKAKNITIKND------ 504
                                                       ::|.|........|||
Zfish   505 EGEEPMETDTPAKDEENKMQVDQEAQKAQADDQKEQADKKSDTEDMETSPEDKQEKKNDQPPQAK 569

  Fly   505 KGRLSQAEIDR------------------MVNEAEKYADEDEKHRQRITSRNALESYVYNVKQSV 551
            |.::....:|.                  |.||. |...:|:..::|..::|.:|.|||.::..:
Zfish   570 KAKVKTKTVDLPIMNSLQWQLASDALNLFMENEG-KMIMQDKLEKERNDAKNYVEEYVYEMRDKL 633

  Fly   552 EQAPAGKLDEADKNSVLDKCNETIRWL-DSNTTAEKEEFDHKMEELARHCSPIMTK 606
            .......:.||:::|...|..:|..|| :.....:|:.:..|:.||.:...||.::
Zfish   634 HGVLENFVSEAERDSFSLKLEDTENWLYEEGEDQQKQVYIDKLAELKKLGDPIQSR 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ba	NP_731716.1	PTZ00009	2..641	CDD:240227	209/705 (30%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	154/388 (40%)
hspa4a	NP_999881.1	NBD_sugar-kinase_HSP70_actin	2..384	CDD:302596	154/389 (40%)
		HSP70	3..692	CDD:278441	209/704 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900