Protein Alignment Hsp70Ba and Hspa12b

DIOPT Version :10

• Sequence 1: NP_731716.1
• Gene: Hsp70Ba / 44921
• FlyBaseID: FBgn0013277
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001381945.1
• Gene: Hspa12b / 311427
• RGDID: 1312004
• Length: 685
• Species: Rattus norvegicus
• Alignment Length: 648
• Identity: 147/648 - (22%)
• Similarity: 235/648 - (36%)
• Gaps: 200/648 - (30%)

  Fly    25 IIANDQGNRTTPSYVAF---TDSERLI-------GDP------AKNQVAMNPRNTVFDAKRLIGR 73
            ::|.|.|  ||.|..||   ||.|.:.       |||      ....:.:.|.. :|.:.....|
  Rat    62 VVAIDFG--TTSSGYAFSFATDPEAIHMMRKWEGGDPGVAHQKTPTCLLLTPEG-IFHSFGYTAR 123

  Fly    74 KYD---DPKIAEDMKHW-PFKV----VSD----------GGKPKIGVEYKGESKRFAPEEISSMV 120
            .|.   ||:.|.|..:: .||:    .:|          .||..:.:|....:.||..|.    .
  Rat   124 DYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKEH----A 184

  Fly   121 LTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPTAAAL- 178
            |.:::|.:|..|.:.....|:||||.:....:|..::|.::|||      ..|.|..||.||::
  Rat   185 LQELREQSECMLEKDAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEAASVY 249

  Fly   179 ----------------AYG--------LDKNLKGERNVL-------------------------- 193
                            |.|        :|.:.:..|..|
  Rat   250 CRKLRLHQLMDLSSRTAGGGRLGERRSIDSSFRHAREQLRRSRHSRTFLVESGVGELWSEMQEGD 314

  Fly   194 ---IFDLGGGTFDVSILTIDE--GSLFEV-RSTAGDTHLGGED--FDNRLVTHLAEEFKRKYKKD 250
               :.|.||||.|:::..:::  |:|.|: :::.|.....|.|  |:..|.....|:|..|:|
  Rat   315 RYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGEDFIAKFK-- 377

  Fly   251 LRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFE-------------- 301
             |..|.|...|..|.|..|||........:.|...|...|||.|......|
  Rat   378 -RQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNFVKWS 441

  Fly   302 ---------ELCADLFRNT----LQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQEFFH 353
                     |...:||:.|    :|.:|..|  ||.:...:..:.||||......:|..:||...
  Rat   442 SQGMLRMSCEAMNELFQPTVSGIIQHIEMLL--AKPEVQGVKLLFLVGGFAESAVLQHAVQEALG 504

  Fly   354 GKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMT--------- 409
            .:.|.:.:..|..:   ..::.|:|.|...|    |:.|..:||:.|:    ||:.
  Rat   505 NRGLRVVVPHDVGL---TILKGAVLFGQAPG----VVRVRRSPLTYGV----GVLNRFVPGHHPP 558

  Fly   410 -KLIERNCRIPCKQTKTFS-----------------TYSDNQPG---VSIQVY----EGERAMT- 448
             ||:.|:.|..|  |..|.                 :|...:||   |.|.:|    |..|.:|
  Rat   559 EKLLVRDGRRWC--TDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFITD 621

  Fly   449 ---KDNNAL-------GTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITI 501
               :...||       |:.:.:|..|:.|.:.......|.:    :.|:|.::||.::....|
  Rat   622 PGVRKCGALSLELEPEGSPENTGTSPSRREIRAAMQFGDTE----IKVTAVDVSTNRSVRAAI 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ba	NP_731716.1	PTZ00009	2..641	CDD:240227	147/648 (23%)
Hspa12b	NP_001381945.1	ASKHA_ATPase-like	61..528	CDD:483947	110/480 (23%)