Protein Alignment Hsp70Ba and Hspa12a

DIOPT Version :10

• Sequence 1: NP_731716.1
• Gene: Hsp70Ba / 44921
• FlyBaseID: FBgn0013277
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001424727.1
• Gene: Hspa12a / 307997
• RGDID: 1305531
• Length: 691
• Species: Rattus norvegicus
• Alignment Length: 659
• Identity: 137/659 - (20%)
• Similarity: 227/659 - (34%)
• Gaps: 208/659 - (31%)

  Fly     4 IGIDLGTTYS-----------CVGVYQHGKVEIIANDQG--NRTTPSYVAFTDSERLIGDPAKNQ 55
            :.||.|||.|           |:.|.:..:    ..|.|  |:.||:.:..|...:.      :.
  Rat    75 VAIDFGTTSSGYAYSFTKEPECIHVMRRWE----GGDPGVSNQKTPTTILLTPERKF------HS 129

  Fly    56 VAMNPRNTVFDAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGE-----------SK 109
            .....|:...|.         ||   .:.|.|.:.     .|.|:.:...|:           .|
  Rat   130 FGYAARDFYHDL---------DP---NEAKQWLYL-----EKFKMKLHTTGDLTMDTDLTAANGK 177

  Fly   110 RFAPEEISSMVLTKMKETAEAYLGESI------TDA--VITVPAYFNDSQRQATKDAGHIAGL-- 164
            :....||.:..|...||.|...|.:..      :|.  ||||||.:....:|..::|.:.|||
  Rat   178 KVKALEIFTYALQYFKEQALKELSDQAGSDFENSDVRWVITVPAIWKQPAKQFMREAAYQAGLAS 242

  Fly   165 ----NVLRIINEPTAAAL--------------------AYG------------------------ 181
                ..|.|..||.||::                    .|.
  Rat   243 PENSEQLIIALEPEAASIYCRKLRLHQMIELSSKAVVNGYSASDTVGAGFAQAKEHVRRNRQSRT 307

  Fly   182 -LDKNLKGE--------RNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH--LGGE-DFD 232
             |.:|:.||        ...::.|.||||.|:::  :.:.||.|.|:....|..:  ||.: :|:
  Rat   308 FLVENVIGEIWSELEEGDKYVVVDSGGGTVDLTVHQIRLPEGHLKELYKATGGPYGSLGVDYEFE 372

  Fly   233 NRLVTHLAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKV-- 295
            ..|.....|:|..::|   ...|.|...|..|.|..||..:......:.|...|...|:|.|.
  Rat   373 KLLCKIFGEDFIEQFK---IKRPAAWVDLMIAFESRKRAAAPDRTNPLNITLPFSFIDYYKKFRG 434

  Fly   296 ---------SRARFEELCAD------------LFRNTLQPVEKALND--AKMDKGQIHDIVLVGG 337
                     |...|.:..:.            ||:.|:..:.:.|.|  .|.:...:..:.||||
  Rat   435 HSVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDSIIEHLRDLFQKPEVSTVKFLFLVGG 499

  Fly   338 STRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVLLVDVAPLSLGI 401
            ....|.:|..:|..| |....:.|..|..:   ..::.|:|.| |.:     |:.|..:||:.|:
  Rat   500 FAEAPLLQQAVQAAF-GDKCRIIIPQDVGL---TILKGAVLFGLDPA-----VIKVRRSPLTYGV 555

  Fly   402 ETAGGVMTKLIE--------------RNCR------IPCKQT--------KTFSTYSDNQPGVSI 438
                ||:.:.:|              |.|.      |...|:        ::::....:|..:.|
  Rat   556 ----GVLNRYVEGKHPPEKLLVKDGTRWCTDVFDKFISADQSVALGELVKRSYTPAKPSQLVIII 616

  Fly   439 QVYEGER---AMTKDNNA--LGT--FDLSGIP----PAPRGVPQIEVTFDLDANGILNVSAKEMS 492
            .:|..|.   :...|...  .||  .||:|..    ||.|.:..:....|.:    :..:|.:::
  Rat   617 NIYSSENDDVSFITDPGVKKCGTLRLDLTGTSGAAVPARREIQTLMQFGDTE----IKATAVDIA 677

  Fly   493 TGKAKNITI 501
            |.|:..:.|
  Rat   678 TSKSVKVGI 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ba	NP_731716.1	PTZ00009	2..641	CDD:240227	137/659 (21%)
Hspa12a	NP_001424727.1	None