Protein Alignment Hsp70Ba and Hspa1l

DIOPT Version :9

• Sequence 1: NP_731716.1
• Gene: Hsp70Ba / 44921
• FlyBaseID: FBgn0013277
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_997711.1
• Gene: Hspa1l / 24963
• RGDID: 1595925
• Length: 641
• Species: Rattus norvegicus
• Alignment Length: 641
• Identity: 475/641 - (74%)
• Similarity: 553/641 - (86%)
• Gaps: 9/641 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |||||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||:||||||
  Rat     8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDA 72

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            |||||||::||.:..|||.|||:|:::.||||:.|.||||.|.|.||||||||||||||||||:|
  Rat    73 KRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVLVSYKGEKKAFYPEEISSMVLTKMKETAEAFL 137

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |.|:|:|||||||||||||||||||||.|||||||||||||||||:||||||...|||:||||||
  Rat   138 GHSVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGSHGERHVLIFDL 202

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262
            |||||||||||||:| :|||::|||||||||||||||||:|..||||||:|||:..|.||:||||
  Rat   203 GGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLR 266

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.|||||||||||:|.:|||:|:||.||||.::|||||||||||||.||:||||:|.||||||.
  Rat   267 TACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKA 331

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            :|||||||||||||||||.|||::|:|::||.|||||||||||||||||||.||:|.|:||:||:
  Rat   332 KIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLL 396

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||||||||:||||||||.||:||..||.|||:.|:|||||||||.|||||||||||:|||.||.|
  Rat   397 DVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRF 461

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            ||:|||||||||||||||||:||||||||:|.:.|||||..|||.|||||||:.||:|||.|||:
  Rat   462 DLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVQEAER 526

  Fly   523 YADEDEKHRQRITSRNALESYVYNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEK 586
            |..|||..|::|.::||||||.:|:|.:| ::....|:.|:||..:||||:|.:.||::|..|||
  Rat   527 YKAEDEGQREKIAAKNALESYAFNMKSAVGDEGLKDKISESDKKKILDKCSEVLSWLEANQLAEK 591

  Fly   587 EEFDHKMEELARHCSPIMTKMHQQG-AGAAGGPGANCGQQAGGFGGYSGPTVEEVD 641
            ||||||.:||...|:||:||::|.| .|....||...|:.|      :|||:||||
  Rat   592 EEFDHKRKELENMCNPIITKLYQSGCTGPTCAPGYTPGRAA------TGPTIEEVD 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ba	NP_731716.1	PTZ00009	2..641	CDD:240227	473/639 (74%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	306/375 (82%)
Hspa1l	NP_997711.1	PTZ00009	3..641	CDD:240227	473/639 (74%)
		Nucleotide-binding domain (NBD). /evidence=ECO:0000250|UniProtKB:P11142	3..388		309/380 (81%)
		Substrate-binding domain (SBD). /evidence=ECO:0000250|UniProtKB:P11142	396..511		91/114 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	O	PTHR19375
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920