Protein Alignment Hsp70Ab and hscA

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_417021.1
• Gene: hscA / 944885
• ECOCYCID: EG12130
• Length: 616
• Species: Escherichia coli
• Alignment Length: 596
• Identity: 232/596 - (38%)
• Similarity: 344/596 - (57%)
• Gaps: 40/596 - (6%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |.|||||||.|.|...:.|:.|.:|:.:|....||.|.:......:|..|:...|::..||:...
E. coli    21 AAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSV 85

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKV-VSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||:||...|  |.:...|.|::. .|:.|.|.|    :..:....|..:|:.:|..:...|...
E. coli    86 KRLMGRSLAD--IQQRYPHLPYQFQASENGLPMI----ETAAGLLNPVRVSADILKALAARATEA 144

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            |...:...||||||||:|:|||.||||..:|||:|||::|||||||:|||||...:|.  :.::|
E. coli   145 LAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGV--IAVYD 207

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||:|||.:..| :|||.:|.||:.|||:|||:.    |||..:.:.....||:.|..|.|
E. coli   208 LGGGTFDISILRLSRG-VFEVLATGGDSALGGDDFDHL----LADYIREQAGIPDRSDNRVQREL 267

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            ..||..||..||.:...|:.: |.::|:     :||.:|.||.|.|.:.||....:||.||.::.
E. coli   268 LDAAIAAKIALSDADSVTVNV-AGWQGE-----ISREQFNELIAPLVKRTLLACRRALKDAGVEA 326

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .::.::|:||||||:|.|:..:.:|| |:....||:||:.||.|||:||.||.|::..  .::||
E. coli   327 DEVLEVVMVGGSTRVPLVRERVGEFF-GRPPLTSIDPDKVVAIGAAIQADILVGNKPD--SEMLL 388

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.|||||:||.||::.|:|.||..||..:.:.|:|:.|.|..:||.|.:|||.:.:|..:|..
E. coli   389 LDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLAR 453

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |.|.|||..|.|...|.|||.:||:|:|:|:|.|.|||...:|.:|...| |:.:||..|:.::.
E. coli   454 FALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYG-LTDSEIASMIKDSM 517

  Fly   522 KYADEDEKHR----QRITSRNALESYVFNV-----------KQAVEQAPAGKLDEADKNSVLDKC 571
            .||::|.|.|    |::.:...|||....:           :|.::.| |..|.|..:...:|..
E. coli   518 SYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDA-AAHLSEVAQGDDVDAI 581

  Fly   572 NDTIRWLDSNT 582
            ...|:.:|..|
E. coli   582 EQAIKNVDKQT 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	232/596 (39%)
hscA	NP_417021.1	hscA	1..616	CDD:235360	232/596 (39%)