Protein Alignment Hsp70Ab and SSA4

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_011029.3
• Gene: SSA4 / 856840
• SGDID: S000000905
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 642
• Identity: 451/642 - (70%)
• Similarity: 522/642 - (81%)
• Gaps: 5/642 - (0%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            |:|||||||||||..:.:.:|||||||||||||||||||||:||||||.||||.||||.||||||
Yeast     4 AVGIDLGTTYSCVAHFANDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQAAMNPHNTVFDA 68

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            |||||||:|||::..|.||:||||:..||||.:.||||||:|.|.|||||||:|||||||||.:|
Yeast    69 KRLIGRKFDDPEVTNDAKHYPFKVIDKGGKPVVQVEYKGETKTFTPEEISSMILTKMKETAENFL 133

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |..:.|||:||||||||||||||||||.|||||||||||||||||:||||||..:.|.|||||||
Yeast   134 GTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKSQKEHNVLIFDL 198

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLR 262
            ||||||||:|:|||| :|||::|||||||||||||:|||..||:|||||.||||.:|.|:|||||
Yeast   199 GGGTFDVSLLSIDEG-VFEVKATAGDTHLGGEDFDSRLVNFLAEEFKRKNKKDLTTNQRSLRRLR 262

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            |||||||||||||.:.:||||:||||.||||.::|||||||||||||:||:||||.|.|:|:||.
Yeast   263 TAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCADLFRSTLEPVEKVLADSKLDKS 327

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            ||.:||||||||||||||.|:.|||:||..|.|||||||||||||||||||:||||...||:||:
Yeast   328 QIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVAYGAAVQAAILTGDQSSTTQDLLLL 392

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||||||||||||||:|||||.||..||.|:::.|||||||||||.|||:||||..|||||.||.|
Yeast   393 DVAPLSLGIETAGGIMTKLIPRNSTIPTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKF 457

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|||||||||||||||||||:||||||||||.|..|||:..|||.|||||||:.:||:||.||||
Yeast   458 ELSGIPPAPRGVPQIEVTFDIDANGILNVSAVEKGTGKSNKITITNDKGRLSKEDIDKMVAEAEK 522

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQAV-EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAEK 586
            :..|||:..||:.::|.||||.|.:|.:| |.....|:.|.|...:.....|.|.|||::..|..
Yeast   523 FKAEDEQEAQRVQAKNQLESYAFTLKNSVSENNFKEKVGEEDARKLEAAAQDAINWLDASQAAST 587

  Fly   587 EEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGG-YSGPTVEEVD 642
            ||:..:.:||....:|||:|.:  ||..||.|.|...|..||..|. .:||||||||
Yeast   588 EEYKERQKELEGVANPIMSKFY--GAAGGAPGAGPVPGAGAGPTGAPDNGPTVEEVD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	449/640 (70%)
SSA4	NP_011029.3	PTZ00009	4..642	CDD:240227	449/640 (70%)