Protein Alignment Hsp70Ab and ECM10

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_010884.1
• Gene: ECM10 / 856682
• SGDID: S000000756
• Length: 644
• Species: Saccharomyces cerevisiae
• Alignment Length: 619
• Identity: 306/619 - (49%)
• Similarity: 419/619 - (67%)
• Gaps: 31/619 - (5%)

  Fly     4 IGIDLGTTYSCVGVYQHGKV-EIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFD 66
            ||||||||.|.|.:.: ||| .||.|.:|:|||||.|||| |.|||:|:|||.|..:|..||:|.
Yeast    30 IGIDLGTTNSAVAIME-GKVPRIIENAEGSRTTPSVVAFTKDGERLVGEPAKRQSVINSENTLFA 93

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            .||||||:::|.::..|:...|||:|  |:|     ....:..::.::|.:|...:|.|||||||
Yeast    94 TKRLIGRRFEDAEVQRDINQVPFKIVKHSNG-----DAWVEARNRTYSPAQIGGFILNKMKETAE 153

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVL- 193
            |||.:|:.:||:||||||||:|||||||||.|.||||||::||||||||||||||:   |..|:
Yeast   154 AYLAKSVKNAVVTVPAYFNDAQRQATKDAGQIIGLNVLRVVNEPTAAALAYGLDKS---EPKVIA 215

  Fly   194 IFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRAL 258
            :|||||||||:|||.||.| :|||:||.|||||||||||..|:..:...||::...||.::..|:
Yeast   216 VFDLGGGTFDISILDIDNG-IFEVKSTNGDTHLGGEDFDIYLLQEIISHFKKETGIDLSNDRMAV 279

  Fly   259 RRLRTAAERAKRTLSS--STEATIE-IDALFEG-QDFYTKVSRARFEELCADLFRNTLQPVEKAL 319
            :|:|.|||:||..|||  |||..:. |.|...| :......||.:.|.:.|.|...|:.||:|||
Yeast   280 QRIREAAEKAKIELSSTLSTEINLPFITADAAGPKHIRMPFSRVQLENITAPLIDRTVDPVKKAL 344

  Fly   320 NDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSG 384
            .||::....|.|::||||.:|:|||...::..| ||:.:.::|||||||.|||:|||:|||:
Yeast   345 KDARITASDISDVLLVGGMSRMPKVADTVKKLF-GKDASKAVNPDEAVALGAAIQAAVLSGE--- 405

  Fly   385 KIQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTK 449
             :.||||:||.||||||||.|||.||||.||..||.|:::.|||.|..|..|.::|::|||.:.|
Yeast   406 -VTDVLLLDVTPLSLGIETLGGVFTKLIPRNSTIPNKKSQIFSTAASGQTSVEVKVFQGERELVK 469

  Fly   450 DNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEID 514
            ||..:|.|.|:||||||:|.||||||||:|||||:|||||::::.|..:||:....| ||..|||
Yeast   470 DNKLIGNFTLAGIPPAPKGTPQIEVTFDIDANGIINVSAKDLASHKDSSITVAGASG-LSDTEID 533

  Fly   515 RMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDEADKNSVLDKCNDTIRWLD 579
            |||||||:|.::|...|..|.:.|..:....:.:.::::. .||||:.|...:.|:.: ::|.|.
Yeast   534 RMVNEAERYKNQDRARRNAIETANKADQLANDTENSIKEF-EGKLDKTDSQRLKDQIS-SLRELV 596

  Fly   580 SNTTAEKEEFDH----KLEELTRHCSPIMTKMHQ 609
            |.:.|..|..|.    |::.|......:..::::
Yeast   597 SRSQAGDEVNDDDVGTKIDNLRTSSMKLFEQLYK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	306/619 (49%)
ECM10	NP_010884.1	dnaK	29..644	CDD:234715	306/619 (49%)