Protein Alignment Hsp70Ab and SSC1

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_012579.1
• Gene: SSC1 / 853503
• SGDID: S000003806
• Length: 654
• Species: Saccharomyces cerevisiae
• Alignment Length: 630
• Identity: 309/630 - (49%)
• Similarity: 425/630 - (67%)
• Gaps: 27/630 - (4%)

  Fly     4 IGIDLGTTYSCVGVYQHGKV-EIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFD 66
            ||||||||.|.|.:.: ||| :||.|.:|:|||||.|||| :.|||:|.|||.|..:||.||:|.
Yeast    33 IGIDLGTTNSAVAIME-GKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFA 96

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            .||||||:::|.::..|:|..|:|:|  |:|   ...||.:|::  ::|.:|...||.|||||||
Yeast    97 TKRLIGRRFEDAEVQRDIKQVPYKIVKHSNG---DAWVEARGQT--YSPAQIGGFVLNKMKETAE 156

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLI 194
            ||||:.:.:||:||||||||||||||||||.|.||||||::||||||||||||:|:  ..:.|.:
Yeast   157 AYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKS--DSKVVAV 219

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALR 259
            |||||||||:|||.||.| :|||:||.|||||||||||..|:..:...||.:...||.::..|::
Yeast   220 FDLGGGTFDISILDIDNG-VFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQ 283

  Fly   260 RLRTAAERAKRTLSS--STEATIE-IDALFEG-QDFYTKVSRARFEELCADLFRNTLQPVEKALN 320
            |:|.|||:||..|||  |||..:. |.|...| :....|.|||:||.|.|.|.:.|:.||:|||.
Yeast   284 RIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALK 348

  Fly   321 DAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGK 385
            ||.:....|.:::||||.:|:|||...::..| ||:.:.::|||||||.|||||.|:|||:
Yeast   349 DAGLSTSDISEVLLVGGMSRMPKVVETVKSLF-GKDPSKAVNPDEAVAIGAAVQGAVLSGE---- 408

  Fly   386 IQDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKD 450
            :.||||:||.||||||||.|||.|:||.||..||.|:::.|||.|..|..|.|:|::|||.:.:|
Yeast   409 VTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRD 473

  Fly   451 NNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDR 515
            |..:|.|.|:||||||:||||||||||:||:||:||||::.:|.|..:||:....| ||:.||::
Yeast   474 NKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSG-LSENEIEQ 537

  Fly   516 MVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDEADKNSVLDK---CNDTIRW 577
            |||:|||:..:||..:|.|.:.|..:....:.:.::::. .||:|:|:...|.|:   ..:.:..
Yeast   538 MVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEF-EGKVDKAEAQKVRDQITSLKELVAR 601

  Fly   578 LDSNTTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGAN 622
            :........||...|.|||......:..::::..:.......|.|
Yeast   602 VQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNGNN 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	309/630 (49%)
SSC1	NP_012579.1	dnaK	30..633	CDD:234715	307/615 (50%)