Protein Alignment Hsp70Ab and hspa12a

DIOPT Version :9

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_017207164.1
• Gene: hspa12a / 751725
• ZFINID: ZDB-GENE-031001-1
• Length: 671
• Species: Danio rerio
• Alignment Length: 682
• Identity: 140/682 - (20%)
• Similarity: 228/682 - (33%)
• Gaps: 250/682 - (36%)

  Fly    19 QHGKVEIIANDQGNRTTPSYVAFTDSERLI--------GDP-AKNQ-----VAMNPRNTVFDAKR 69
            :|..|.::|.|.|..::....|||.....|        ||| ..||     :.:.| :..|.:..
Zfish    50 RHHFVVVVAIDFGTTSSGYAYAFTKEPECIHTMRRWEGGDPGVSNQKTPTTILLTP-DKKFHSFG 113

  Fly    70 LIGRKYDDPKIAEDMKHW----PFKV---------------VSDGGKPKIGVEYKGESKRFAPEE 115
            ...|.:.......:.|.|    .||:               .::|.|.| .::....:..|..|:
Zfish   114 YAARDFYHDLDPTESKQWLYLEKFKMKLHTTANLSIDTDLHAANGKKVK-ALDIFAYALAFFKEQ 177

  Fly   116 ISSMVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPT 174
                .|.::.:.|.|....:....||||||.:....:|..::|.:.|.|      :.|.|..||.
Zfish   178 ----ALKELSDQAGAEFDNADVRWVITVPAIWKMPAKQFMREAAYKAALVTRENPDQLIIALEPE 238

  Fly   175 AAAL--------------------AYGLDKN---------------------------------- 185
            ||::                    .|....|
Zfish   239 AASIYCRKLRLHQMVDLGSKTALNGYSPTDNAGVGMTQAKEHVRRNRQSRTFLVENVIGELWSEL 303

  Fly   186 LKGERNVLIFDLGGGTFDVSI--LTIDEGSLFEVRSTAGDTH---------------LGGEDFDN 233
            .:|:|.|:: |.||||.|:::  :.:.||.|.|:...:|..:               :.|:||
Zfish   304 AEGDRYVVV-DCGGGTVDLTVHQIRLPEGHLKELYKASGGPYGSIGIDYEFEKLLCKIFGQDF-- 365

  Fly   234 RLVTHLADEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKV--- 295
                  .|:||.|       .|.|...|..|.|..||..:......:.|:..|...|:|.|.
Zfish   366 ------IDQFKIK-------RPAAWVDLMIAFESRKRAATPDRSNPLNINLPFSFIDYYKKFRGH 417

  Fly   296 --------SRARFEELCAD------------LFRNTLQPVEKALNDAKMDKGQIHDI---VLVGG 337
                    |...|.:..:.            ||:.|:..:.:.|.:. .|:.::.||   .||||
Zfish   418 SVEHALRKSNVDFVKWSSQGMLRMSPDAMNALFKPTIDHIIQHLTEL-FDRPEVTDIKFLFLVGG 481

  Fly   338 STRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVLLVDVAPLSLGI 401
            ....|.:|..:|:...|:: .:.|..|..:   ..::.|:|.| |.|     ::.|..:||:.|:
Zfish   482 FAESPLLQQAVQNMLQGRS-RIIIPHDVGL---TILKGAVLFGLDPS-----IIKVRRSPLTYGV 537

  Fly   402 ETAGGVMTKLIE--------------RNCRIPCKQTKTFSTY--AD------------------N 432
                ||:.:.:|              |.|      |..|.|:  ||                  :
Zfish   538 ----GVLNRFVEGKHPPEKMLVKDGMRWC------TDVFDTFISADQSVALGETVKRSYTPAKPS 592

  Fly   433 QPGVSIQVYEGERAMTKDNNALGTF--------------DLSGI-PPAPRGVPQIEVTFDLDANG 482
            |..:.|.||..|:...       ||              |:||. .||.|...|..:.|.
Zfish   593 QQVIVIHVYCSEKESV-------TFITDPGVRKCGSLKLDVSGTESPAARREIQTLMQFG----- 645

  Fly   483 ILNVSAKEMSTGKAKNITIKNDKGRLSQAEID 514
              :...:.|:...|.:.|:|        |.||
Zfish   646 --DTEIRAMAVDVATSRTVK--------ASID 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	140/682 (21%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	100/495 (20%)
hspa12a	XP_017207164.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810