Protein Alignment Hsp70Ab and Hspa12b

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_082582.1
• Gene: Hspa12b / 72630
• MGIID: 1919880
• Length: 685
• Species: Mus musculus
• Alignment Length: 650
• Identity: 144/650 - (22%)
• Similarity: 232/650 - (35%)
• Gaps: 204/650 - (31%)

  Fly    25 IIANDQGNRTTPSYVAF---TDSERLI-------GDPAKNQVAMNPRNT--------VFDAKRLI 71
            ::|.|.|  ||.|..||   :|.|.:.       |||.   ||.....|        :|.:....
Mouse    62 VVAIDFG--TTSSGYAFSFASDPEAIHMMRKWEGGDPG---VAHQKTPTCLLLTPEGIFHSFGYT 121

  Fly    72 GRKYD---DPKIAEDMKHW-PFKV----VSD----------GGKPKIGVEYKGESKRFAPEEISS 118
            .|.|.   ||:.|.|..:: .||:    .:|          .||..:.:|....:.||..|.
Mouse   122 ARDYYHDLDPEEARDWLYFEKFKMKIHSATDLTLKTQLEAVNGKKMLALEVFAHALRFFKEH--- 183

  Fly   119 MVLTKMKETAEAYLGESITDAVITVPAYFNDSQRQATKDAGHIAGL------NVLRIINEPTAAA 177
             .|.:::|.:|..|.:.....|:||||.:....:|..::|.::|||      ..|.|..||.||:
Mouse   184 -ALQELREQSECMLEKGAVRWVLTVPAIWKQPAKQFMREAAYLAGLVSREDAEKLLIALEPEAAS 247

  Fly   178 L-------------------------AYGLDKNLKGERNVL------------------------ 193
            :                         ...:|.:.:..|..|
Mouse   248 VYCRKLRLHQLMDLSSRTAGRGRLGERRSIDSSFRHAREQLRRSRHSRTFLVEAGVGELWAEMQE 312

  Fly   194 -----IFDLGGGTFDVSILTIDE--GSLFEV-RSTAGDTHLGGED--FDNRLVTHLADEFKRKYK 248
                 :.|.||||.|:::..:::  |:|.|: :::.|.....|.|  |:..|.....::|..|:|
Mouse   313 GDRYMVADCGGGTVDLTVHQLEQPHGTLKELYKASGGPYGAVGVDLAFEQLLCRIFGEDFIAKFK 377

  Fly   249 KDLRSNPRALRRLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFE------------ 301
               |..|.|...|..|.|..|||........:.|...|...|||.|......|
Mouse   378 ---RQRPAAWVDLTIAFEARKRTAGPHRAGALNISLPFSFIDFYRKQRGHNVETALRRSSVNLVK 439

  Fly   302 -----------ELCADLFRNT----LQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLLQDF 351
                       |...:||:.|    :|.:|..|  ||.:...:..:.||||......:|..:|:.
Mouse   440 WSSQGMLRMSCEAMNELFQPTVSGIIQHIEMLL--AKPEVQGVKLLFLVGGFAESAVLQHAVQEA 502

  Fly   352 FHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLVDVAPLSLGIETAGGVMT------- 409
            ...:.|.:.:..|..:   ..::.|:|.|...|    |:.|..:||:.|:    ||:.
Mouse   503 LGTRGLRVVVPHDVGL---TILKGAVLFGQAPG----VVRVRRSPLTYGV----GVLNRFVPGHH 556

  Fly   410 ---KLIERNCRIPCKQTKTFS-----------------TYADNQPG---VSIQVY----EGERAM 447
               ||:.|:.|..|  |..|.                 :|...:||   |.|.:|    |..|.:
Mouse   557 PPEKLLVRDGRRWC--TDVFERFVAAEQSVALGEEVRRSYCPARPGQRRVLINLYCCAAEDARFI 619

  Fly   448 T----KDNNAL-------GTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITI 501
            |    :...||       |..:.:|..|:.|.:.......|.:    :.|:|.::||.::....|
Mouse   620 TDPGVRKCGALSLELEPEGCPENTGTSPSRREIRAAMQFGDTE----IKVTAVDVSTNRSVRAAI 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	143/649 (22%)
Hspa12b	NP_082582.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50
		ASKHA_ATPase-like	61..528	CDD:483947	107/482 (22%)