Protein Alignment Hsp70Ab and HSPA13

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_008879.3
• Gene: HSPA13 / 6782
• HGNCID: 11375
• Length: 471
• Species: Homo sapiens
• Alignment Length: 422
• Identity: 161/422 - (38%)
• Similarity: 244/422 - (57%)
• Gaps: 51/422 - (12%)

  Fly     4 IGIDLGTTYSCVGVY--QHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            |||||||||..|||:  ..|||::|.::.|:.:.||.|:|||::..:|..:......||:||::|
Human    34 IGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNPQNTIYD 98

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||.||:.:...::..::..:||||::..|..:..|. ..|:...:||.:.|.:|.|:||.||||
Human    99 AKRFIGKIFTAEELEAEIGRYPFKVLNKNGMVEFSVT-SNETITVSPEYVGSRLLLKLKEMAEAY 162

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||..:.:|||:|||.|:..||.:|.:|.::|||.:||:||||||||:||||.|  ....:||:.|
Human   163 LGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMAYGLHK--ADVFHVLVID 225

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||.|||:|. .:|.:|..|:.:|:..|||:||:.||:.:|..:..:.| ..:.|....:.||
Human   226 LGGGTLDVSLLN-KQGGMFLTRAMSGNNKLGGQDFNQRLLQYLYKQIYQTY-GFVPSRKEEIHRL 288

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQD------------------------------------ 290
            |.|.|..|..|:....|.:.:....|.||
Human   289 RQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHSSDTELPKDKLSSADDHRVNSGFGRGLSDKK 353

  Fly   291 -------FYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKGQIHDIVLVGGSTRIPKVQSLL 348
                   |.|::||..|:.|..|||:..|.|:::.|.:..::|.:|.::||||||||||:::.::
Human   354 SGESQVLFETEISRKLFDTLNEDLFQKILVPIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVI 418

  Fly   349 QDFFHGKNLNLSINPDEAVAYGAAVQAAILSG 380
            |:|| ||:.|.|::||.||..|.|:||.|..|
Human   419 QEFF-GKDPNTSVDPDLAVVTGVAIQAGIDGG 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	161/422 (38%)
HSPA13	NP_008879.3	ASKHA_NBD_HSP70_HSPA13	10..452	CDD:466835	161/422 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	315..352		2/36 (6%)