Protein Alignment Hsp70Ab and hspa8b

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001186941.1
• Gene: hspa8b / 562935
• ZFINID: ZDB-GENE-121214-31
• Length: 647
• Species: Danio rerio
• Alignment Length: 648
• Identity: 477/648 - (73%)
• Similarity: 552/648 - (85%)
• Gaps: 12/648 - (1%)

  Fly     2 PAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            ||:|||||||||||||:|||||||||||||||||||||||||:||||||.||||||:||.|||||
Zfish     5 PAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPTNTVFD 69

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||::||..:..|||||||.|::|..:||:.||||||:|.|.|||:||||||||||.||||
Zfish    70 AKRLIGRRFDDAVVQSDMKHWPFTVINDNLRPKVQVEYKGETKTFYPEEVSSMVLTKMKEIAEAY 134

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||::||:|||||||||||||||||||||.|:|||||||||||||||:||||||.:..||||||||
Zfish   135 LGKTITNAVITVPAYFNDSQRQATKDAGTISGLNVLRIINEPTAAAIAYGLDKKVGSERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:|||...|||||||||:..|.||:|||
Zfish   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVTHFISEFKRKYKKDISDNKRAVRRL 263

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |||.|||||||||||:|:||||:|:||.||||.::|||||||.|||||.||.||||:|.|||:||
Zfish   264 RTACERAKRTLSSSTQASIEIDSLYEGIDFYTSITRARFEELNADLFRGTLDPVEKSLRDAKLDK 328

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .|:||||||||||||||:|.||||||:||.||.|||||||||||||||||||.||:|..:||:||
Zfish   329 SQVHDIVLVGGSTRIPKIQKLLQDFFNGKELNKSINPDEAVAYGAAVQAAILCGDKSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.||||||||||||||.||:||..||.|||:||:||.||||||.|||||||||||||||.||.
Zfish   394 LDVTPLSLGIETAGGVMTILIKRNTTIPTKQTQTFTTYCDNQPGVLIQVYEGERAMTKDNNLLGK 458

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |:|:|||||||||||||||||:|||||:||||.:.||||...|||.|||||||:.:|:|||.|||
Zfish   459 FELTGIPPAPRGVPQIEVTFDIDANGIMNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAE 523

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQAVE-QAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            ||..||:..|::::::|.||||.||:|..|| :...||:.|.||..:::|||:.|.|||.|.|||
Zfish   524 KYKAEDDVQREKVSAKNGLESYSFNMKSTVEDEKLKGKISEEDKQKIINKCNEVISWLDKNQTAE 588

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGA------GAGGPGANCGQQAGGFGGYSGPTVEEVD 642
            ||||:|:.:||.:.|:||:||:: ||.|.      |.|.|||  |...|| ||.||||:||||
Zfish   589 KEEFEHQQKELEKLCNPIITKLY-QGTGGMPEGMPGGGFPGA--GGAPGG-GGSSGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	475/646 (74%)
hspa8b	NP_001186941.1	PTZ00009	1..613	CDD:240227	456/609 (75%)