Protein Alignment Hsp70Ab and Hspa14

DIOPT Version :9

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_056580.2
• Gene: Hspa14 / 50497
• MGIID: 1354164
• Length: 509
• Species: Mus musculus
• Alignment Length: 512
• Identity: 180/512 - (35%)
• Similarity: 290/512 - (56%)
• Gaps: 16/512 - (3%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |.|||:.||.|.:||.||:.|:.:::|||.|:|.||:.||:::.|:::|..||.....:..:||.
Mouse     1 MAAIGVHLGCTSACVAVYKDGRADVVANDAGDRVTPAIVAYSEREQVVGLAAKQSRIRHVSSTVV 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            ..|:::||...||:..:.:......|:...||.:..::...|:|...||:::.::.:||||||.:
Mouse    66 KVKQILGRSSADPQAQKYISESKCLVIEKNGKLRYEIDTGEETKLVNPEDVARLIFSKMKETAHS 130

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDK-NLKGERNVLI 194
            .||....|.|:|||..|.:.|:.|..:|...||.||||:|:||:||.||||:.: :..|:.|||:
Mouse   131 VLGSDANDVVVTVPFDFGEKQKSALGEAAGAAGFNVLRLIHEPSAALLAYGIGQDHPTGKSNVLV 195

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALR 259
            |.|||.:..:|::.::.| ::.|.||....::||..|.:.|..:||.||:|.:|.|:|.|.||:.
Mouse   196 FKLGGTSLSLSVMEVNSG-MYRVLSTNTSDNIGGAHFTDTLAQYLASEFQRLFKHDVRGNARAMM 259

  Fly   260 RLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKM 324
            :|..:||.||.:||:...|...:|:|:|||||...|||||||.||:.||....:.:.:.|.....
Mouse   260 KLMNSAEVAKHSLSTLGSANCFVDSLYEGQDFDCNVSRARFELLCSPLFNKCTEAIRELLRQTGF 324

  Fly   325 DKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDV 389
            ....|:.:||.|||:||||:|.|::|.|...:|..||.|||.:..|||::|.||.|.:|....|.
Mouse   325 TADDINKVVLCGGSSRIPKLQQLIKDLFPAVDLLNSIPPDEVIPIGAAIEAGILVGKESTSGDDS 389

  Fly   390 LLVDVAP---LSLGIETAGG-VMTKLIERNCRIPCKQTKTFSTYADNQPG----VSIQVYEGE-R 445
            ::::.:.   |..|::.:|. ..|.|......:|.::..|...     ||    |.:::||.| :
Mouse   390 VMIECSAKDILVKGVDESGADRFTVLFPSGTPLPARRQHTLQA-----PGRVSSVCLELYESEGK 449

  Fly   446 AMTKDNNALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIK 502
            ...|:........|..:.....|:..|.....:..:|.|.|:..:..|||.:.||::
Mouse   450 NSAKEEAKFAQVVLQDLDKKENGLRDILAVLTMKRDGSLQVTCTDQDTGKCEAITVE 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	179/511 (35%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	150/376 (40%)
Hspa14	NP_056580.2	HSPA14-like_NBD	2..376	CDD:212680	148/374 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810