Protein Alignment Hsp70Ab and Hsc70-4

DIOPT Version :9

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001262586.1
• Gene: Hsc70-4 / 41840
• FlyBaseID: FBgn0266599
• Length: 651
• Species: Drosophila melanogaster
• Alignment Length: 650
• Identity: 484/650 - (74%)
• Similarity: 554/650 - (85%)
• Gaps: 12/650 - (1%)

  Fly     2 PAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            ||:|||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||..|:||
  Fly     5 PAVGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTQTIFD 69

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            ||||||||:||..:..|||||||:|||..|||||.|.||.|.|.|.|||||||||||||||||||
  Fly    70 AKRLIGRKFDDAAVQSDMKHWPFEVVSADGKPKIEVTYKDEKKTFFPEEISSMVLTKMKETAEAY 134

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||:::|:|||||||||||||||||||||.|||||||||||||||||:||||||...|||||||||
  Fly   135 LGKTVTNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKAVGERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||||||:||:| :|||:||||||||||||||||||||...|||||:||||.:|.||||||
  Fly   200 LGGGTFDVSILSIDDG-IFEVKSTAGDTHLGGEDFDNRLVTHFVQEFKRKHKKDLTTNKRALRRL 263

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |||.|||||||||||:|:||||:||||.||||.::|||||||.|||||:|:.||||||.|||:||
  Fly   264 RTACERAKRTLSSSTQASIEIDSLFEGTDFYTSITRARFEELNADLFRSTMDPVEKALRDAKLDK 328

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            ..|||||||||||||||||.||||.|:||.||.|||||||||||||||||||.||:|.::||:||
  Fly   329 SVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGDKSQEVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.|||||||||||||:.||:||..||.|||:||:||:||||||.|||||||||||||||.||.
  Fly   394 LDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGK 458

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |:|||||||||||||||||||:||||||||:|.|.||.|...|||.|||||||:.:|:|||||||
  Fly   459 FELSGIPPAPRGVPQIEVTFDIDANGILNVTALERSTNKENKITITNDKGRLSKEDIERMVNEAE 523

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQAV-EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            ||.:||||.::.|.::|.||||.||:|..: |.....|:.::|:.::|||||:||:|||:|..|:
  Fly   524 KYRNEDEKQKETIAAKNGLESYCFNMKATLDEDNLKTKISDSDRTTILDKCNETIKWLDANQLAD 588

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAG-------AGAGG-PGANCGQQAGGFGGYSGPTVEEVD 642
            |||::|:.:||...|:||:||:: ||||       .|.|| |||.....|.|.|| :|||:||||
  Fly   589 KEEYEHRQKELEGVCNPIITKLY-QGAGFPPGGMPGGPGGMPGAAGAAGAAGAGG-AGPTIEEVD 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	482/648 (74%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	311/375 (83%)
Hsc70-4	NP_001262586.1	PTZ00009	1..612	CDD:240227	463/608 (76%)
		HSPA1-2_6-8-like_NBD	6..381	CDD:212675	311/375 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440307
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	1	1.100	-	-	P	PTHR19375
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.750