Protein Alignment Hsp70Ab and Hsc70-2

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_524339.1
• Gene: Hsc70-2 / 41609
• FlyBaseID: FBgn0001217
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 642
• Identity: 478/642 - (74%)
• Similarity: 553/642 - (86%)
• Gaps: 13/642 - (2%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            :||||||||||||||||:|:.||||||||||||||||||||.::|||||||||||||||.:||||
  Fly     4 IPAIGIDLGTTYSCVGVWQNSKVEIIANDQGNRTTPSYVAFNETERLIGDPAKNQVAMNAKNTVF 68

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            |||||||||:||.||.||:|.|||||:::.|||||.||:|||.||||||||||||||||:|.||.
  Fly    69 DAKRLIGRKFDDKKIQEDLKLWPFKVINEKGKPKIEVEFKGERKRFAPEEISSMVLTKMREIAEV 133

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195
            |||..:.|||:||||||||||||||||||.|||||||||||||||||||||||||||||||||||
  Fly   134 YLGGKVKDAVVTVPAYFNDSQRQATKDAGSIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 198

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRR 260
            ||||||||||:|:|||||||||::|||||||||||||||||.|.|:|||||:|.|::.|.|||||
  Fly   199 DLGGGTFDVSVLSIDEGSLFEVKATAGDTHLGGEDFDNRLVNHFAEEFKRKHKSDIKGNARALRR 263

  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMD 325
            ||||.|||||||||||||::|||||.||.|||:|:||||||||..||||:|:||||:||:|||||
  Fly   264 LRTACERAKRTLSSSTEASLEIDALHEGIDFYSKISRARFEELNMDLFRSTMQPVERALSDAKMD 328

  Fly   326 KGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVL 390
            |..|||:|||||||||||:|.||||.|.||.||||||||||||||||||||||:|..|.:|||:|
  Fly   329 KKAIHDVVLVGGSTRIPKIQKLLQDLFGGKQLNLSINPDEAVAYGAAVQAAILTGVGSSQIQDLL 393

  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALG 455
            |||||||||||||||||||.|:|||.||||||.:.|:||:|||..|:|||||||||||||||.||
  Fly   394 LVDVAPLSLGIETAGGVMTNLVERNARIPCKQQQIFTTYSDNQNAVTIQVYEGERAMTKDNNLLG 458

  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520
            ||:|:||||||||||||||.|||:|:|||||:||:.||||::.|||.|||||||:||||||::||
  Fly   459 TFNLTGIPPAPRGVPQIEVAFDLNADGILNVNAKDNSTGKSEKITISNDKGRLSKAEIDRMLSEA 523

  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            |||..||::.|:|:.|:|.||:|::..:|||:.||:|.|.|.:::.|.|||:....|||.|:.||
  Fly   524 EKYKVEDDRQRERVQSKNNLEAYIYACRQAVDDAPSGVLSETERSKVRDKCSSEASWLDKNSLAE 588

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGGYSGPTVEEVD 642
            ||||:..|:|..|.|:|||:|:|           |...|:.:.|.|  |.|||||||
  Fly   589 KEEFESHLKECQRICTPIMSKIH-----------GGKKGKSSMGKG--SHPTVEEVD 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	476/639 (74%)
Hsc70-2	NP_524339.1	PTZ00009	1..632	CDD:240227	476/640 (74%)