Protein Alignment Hsp70Ab and Hsp110

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001189103.1
• Gene: Hsp110 / 39557
• FlyBaseID: FBgn0026418
• Length: 836
• Species: Drosophila melanogaster
• Alignment Length: 704
• Identity: 202/704 - (28%)
• Similarity: 342/704 - (48%)
• Gaps: 99/704 - (14%)

  Fly     1 MPAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVF 65
            |..||||.|.....|...:.|.:|.:|||...|.|||:|||...:|:||..||||...|.:|||.
  Fly     1 MSVIGIDFGNESCYVAAARSGGIETLANDYSLRATPSFVAFDGKKRIIGVAAKNQQVTNMKNTVG 65

  Fly    66 DAKRLIGRKYDDPKIAEDMKHWPFKVVSDG-GKPKIGVEYKGESKRFAPEEISSMVLTKMKETAE 129
            ..|||:|||::||.:..::...|.:|.:.| |...|.|.|.||.:.|.||::::|:.||:|||:.
  Fly    66 GFKRLLGRKFNDPHVQHELTSIPARVEARGDGSIGIKVNYLGEDQHFGPEQLTAMLFTKLKETSA 130

  Fly   130 AYLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGE---RN 191
            |.:...:.|.||..|.:|.:::|:|..||..||||||||::||.||.|||||..||...|   ||
  Fly   131 AAMQTQVNDCVIACPVFFTNAERKALLDAAQIAGLNVLRLMNETTATALAYGFYKNDLFEDKPRN 195

  Fly   192 VLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPR 256
            |:..|.|..:...|.....:|.|..:.||.  ..:||.|.|..|..:.|.||:.:||.:.::|.|
  Fly   196 VIFVDFGHSSLQASACAFTKGKLKMLASTW--DQIGGRDIDLALGDYFAKEFQERYKINAKTNAR 258

  Fly   257 ALRRLRTAAERAKRTLS-SSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALN 320
            |..||.|..|:.|:.:| :||:..:.|:...:..|..:.:.|::.|||||.:.:...|..::.|.
  Fly   259 ANLRLLTEIEKLKKQMSANSTKLPLNIECFLDDIDVSSSMQRSQMEELCAPVLQRVEQTFKRLLA 323

  Fly   321 DAKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGK 385
            ::|:....||.:.:||||:|||.|:.|::..|: |..:.::|.||||:.|||:|.||:|  .:.:
  Fly   324 ESKLQLDDIHSVEIVGGSSRIPSVKQLIEQVFN-KPASTTLNQDEAVSRGAALQCAIMS--PAVR 385

  Fly   386 IQDVLLVDVAPLSLGI--ETAGGVMTKLIERNCRIPCKQTKTFSTYAD-NQPG-VSIQVYEGERA 446
            :::..:.|:...::.:  ::.|......||   ..|......||.... |:.| .::.:..|::.
  Fly   386 VREFGVTDIQNYAVKVLWDSEGSAAPGEIE---IFPQYHASPFSRLLTINRKGPFNVSIVYGQQV 447

  Fly   447 MTKDNNALGTFDLSGIPPAPRGVPQ-IEVTFDLDANGILNVSA---------------------- 488
            ...| ..:|.:.:..:.|..||..| :::...::.|||:.:|:
  Fly   448 PYPD-QTIGVWKVKDVKPTERGEGQDVKLKVRINNNGIVLISSATLVEKKEAEEAAAAAEQAASE 511

  Fly   489 ------------------------------------------------------KEMSTGKAKNI 499
                                                                  |:....||..:
  Fly   512 EKPGDQTNNTGEPADGQQEAYCENEDDNNTSTASSPGGQGWAQRVKGWFGSGADKKKKASKATEL 576

  Fly   500 TIKNDKGRLSQAEIDRMVNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGK-LDEAD 563
            .::......|..::.....:..|....|:|..:||.::||||.:|::::..::..|..: :.||:
  Fly   577 PLECTTHGFSPVDLSNYTQQESKMIGNDQKETERIDAKNALEEFVYDMRNKLQGGPFERYVVEAE 641

  Fly   564 KNSVLDKCNDTIRWL-DSNTTAEKEEFDHKLEELTRHCSPIMTKM--HQQGAGA 614
            :..::.:.||...|| :.....|::.:..:|:.|.:...||..:.  ::||..|
  Fly   642 REKIVSQLNDLENWLYEDGEDCERDIYTSRLQALHQKTDPIKLRASDYEQGPAA 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	201/703 (29%)
Hsp110	NP_001189103.1	ASKHA_NBD_HSP70_HSPA4_like	4..378	CDD:466826	149/376 (40%)