Protein Alignment Hsp70Ab and hsc70

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_956908.1
• Gene: hsc70 / 393586
• ZFINID: ZDB-GENE-040426-1221
• Length: 647
• Species: Danio rerio
• Alignment Length: 644
• Identity: 474/644 - (73%)
• Similarity: 549/644 - (85%)
• Gaps: 4/644 - (0%)

  Fly     2 PAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            ||:||||||||||||::|||||||||||||||||||||||||:||||||.|||||||||.|||||
Zfish     5 PAVGIDLGTTYSCVGIFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPSNTVFD 69

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||::|||.:..|||||||||:|||.|||:.||||||.|.|.|||:||||||||||.:|||
Zfish    70 AKRLIGRRFDDPVVQSDMKHWPFKVISDGSKPKMEVEYKGEIKTFFPEEVSSMVLTKMKEISEAY 134

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||:::::|||||||||||||||||||||.|||||||||||||||||:||||||.:.|||||||||
Zfish   135 LGKTVSNAVITVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGLDKKVGGERNVLIFD 199

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||||||||::| :|||:||||||||||||||||:|.|...|||||:|||:..|.||:|||
Zfish   200 LGGGTFDVSILTIEDG-IFEVKSTAGDTHLGGEDFDNRMVNHFITEFKRKFKKDITGNKRAVRRL 263

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |||.|||||||||||:|:||||:|:||.||||.::|||||||.|||||.||:||||||.||||||
Zfish   264 RTACERAKRTLSSSTQASIEIDSLYEGADFYTSITRARFEELNADLFRGTLEPVEKALRDAKMDK 328

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLL 391
            .||||||||||||||||:|.||||||:|::||.|||||||||||||||||||:||.|..:||:||
Zfish   329 AQIHDIVLVGGSTRIPKIQKLLQDFFNGRDLNKSINPDEAVAYGAAVQAAILTGDTSENVQDLLL 393

  Fly   392 VDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGT 456
            :||.||||||||||||||.||:||..||.|||:||:||:||||||.|||||||||||||||.||.
Zfish   394 LDVTPLSLGIETAGGVMTVLIKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNILGK 458

  Fly   457 FDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAE 521
            |:|:|||||||||||||||||:||||||||||.:.||||...|||.|||||||:.:|:|||.||:
Zfish   459 FELTGIPPAPRGVPQIEVTFDIDANGILNVSAVDKSTGKENKITITNDKGRLSKEDIERMVQEAD 523

  Fly   522 KYADEDEKHRQRITSRNALESYVFNVKQAVEQAP-AGKLDEADKNSVLDKCNDTIRWLDSNTTAE 585
            :|..|||..|:::|::|.|||..||:|..||... ..|:...||.::.||||:.|.|||.|.|||
Zfish   524 QYRAEDEVQREKVTAKNTLESLAFNMKSTVEDDKLQDKISPEDKKTITDKCNEVISWLDKNQTAE 588

  Fly   586 KEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAG--GFGGYSGPTVEEVD 642
            |:|::|:.:||.:.|:||:||::|...|...|.||...|...|  |.|..||||:||||
Zfish   589 KDEYEHQQKELEKVCNPIITKLYQGAGGMPGGMPGGMPGGYPGGQGSGSSSGPTIEEVD 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	472/642 (74%)
hsc70	NP_956908.1	PTZ00009	1..612	CDD:240227	457/607 (75%)