Protein Alignment Hsp70Ab and hsp-6

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001370558.1
• Gene: hsp-6 / 178873
• WormBaseID: WBGene00002010
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 622
• Identity: 312/622 - (50%)
• Similarity: 427/622 - (68%)
• Gaps: 21/622 - (3%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT-DSERLIGDPAKNQVAMNPRNTVFDA 67
            ||||||||.|||.:.:....::|.|.:|.|||||.|||| |.|||:|.|||.|...|..||:|..
 Worm    34 IGIDLGTTNSCVSIMEGKTPKVIENAEGVRTTPSTVAFTADGERLVGAPAKRQAVTNSANTLFAT 98

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVV--SDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEA 130
            ||||||:|:||::.:|:|..|:|:|  |:|   ...||.:|  |.::|.::.:.||.|||||||:
 Worm    99 KRLIGRRYEDPEVQKDLKVVPYKIVKASNG---DAWVEAQG--KVYSPSQVGAFVLMKMKETAES 158

  Fly   131 YLGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIF 195
            |||.::.:||:||||||||||||||||||.|:||||||:|||||||||||||||: .|::.:.::
 Worm   159 YLGTTVNNAVVTVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALAYGLDKD-AGDKIIAVY 222

  Fly   196 DLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRR 260
            ||||||||||||.|.:| :|||:||.|||.|||||||:.||.||..|||::...||..:|:|::|
 Worm   223 DLGGGTFDVSILEIQKG-VFEVKSTNGDTFLGGEDFDHALVHHLVGEFKKEQGVDLTKDPQAMQR 286

  Fly   261 LRTAAERAKRTLSSSTEATIEIDALFEGQD----FYTKVSRARFEELCADLFRNTLQPVEKALND 321
            ||.|||:||..|||:|:..|.:..:...|.    ...|::||:||::..||.:.|::|..|||:|
 Worm   287 LREAAEKAKCELSSTTQTDINLPYITMDQSGPKHLNLKLTRAKFEQIVGDLIKRTIEPCRKALHD 351

  Fly   322 AKMDKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKI 386
            |::...||.|::||||.:|:||||:.:|:.| ||..:.::|||||||.|||:|.|:|:||    :
 Worm   352 AEVKSSQIADVLLVGGMSRMPKVQATVQEIF-GKVPSKAVNPDEAVAMGAAIQGAVLAGD----V 411

  Fly   387 QDVLLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDN 451
            .||||:||.||||||||.||:|||||.||..||.|:::.|||.||.|..|.|:|::|||.|...|
 Worm   412 TDVLLLDVTPLSLGIETLGGIMTKLITRNTTIPTKKSQVFSTAADGQTQVQIKVFQGEREMATSN 476

  Fly   452 NALGTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRM 516
            ..||.|.|.|||||||||||:|||||:|||||:||||::..|||.:.|.|:: .|.||:.:|:.|
 Worm   477 KLLGQFSLVGIPPAPRGVPQVEVTFDIDANGIVNVSARDRGTGKEQQIVIQS-SGGLSKDQIENM 540

  Fly   517 VNEAEKYADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDEADKNSVLDKCNDTIRWLDSN 581
            :.||||.|.||.|.::.:...|..|..:.:.:..:.:. |.:|.:.:..::..|..||.:.||:.
 Worm   541 IKEAEKNAAEDAKRKELVEVINQAEGIIHDTEAKMTEF-ADQLPKDECEALRTKIADTKKILDNK 604

  Fly   582 TTAEKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGG 618
            .....|........|.:....:....::..|...:||
 Worm   605 DNETPEAIKEACNTLQQQSLKLFEAAYKNMAAKNSGG 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	312/622 (50%)
hsp-6	NP_001370558.1	dnaK	30..646	CDD:234715	312/622 (50%)