Protein Alignment Hsp70Ab and hsp-4

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001370395.1
• Gene: hsp-4 / 174203
• WormBaseID: WBGene00002008
• Length: 657
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 362/628 - (57%)
• Similarity: 473/628 - (75%)
• Gaps: 16/628 - (2%)

  Fly     4 IGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFT--DSERLIGDPAKNQVAMNPRNTVFD 66
            ||||||||||||||:::|:|||||||||||.|||||||:  ..||||||.||||:.:||.||:||
 Worm    33 IGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFSGDQGERLIGDAAKNQLTINPENTIFD 97

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||.|::..:.:|:||||||:|....||.:.|:...|:|:|.|||:|:|||||||:.||:|
 Worm    98 AKRLIGRFYNEKTVQQDIKHWPFKIVDKSNKPNVEVKVGSETKQFTPEEVSAMVLTKMKQIAESY 162

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFD 196
            ||..:.:||:||||||||:|:|||||||.||||||:||||||||||:||||||. .||||:|:||
 Worm   163 LGHEVKNAVVTVPAYFNDAQKQATKDAGSIAGLNVVRIINEPTAAAIAYGLDKK-DGERNILVFD 226

  Fly   197 LGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRL 261
            |||||||||:||||.| :|||.:|.|||||||||||.|::.:....:|:|..||||.:.||:::|
 Worm   227 LGGGTFDVSLLTIDSG-VFEVLATNGDTHLGGEDFDQRVMEYFIKLYKKKSGKDLRKDNRAVQKL 290

  Fly   262 RTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDK 326
            |...|:|||.||:..:..|||::||:|:||...::||:||||..||||.||:||:|.|.||.|.|
 Worm   291 RREVEKAKRALSTQHQTKIEIESLFDGEDFSETLTRAKFEELNMDLFRATLKPVQKVLEDADMKK 355

  Fly   327 GQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSG-DQSGKIQDVL 390
            ..:|:||||||||||||||.|::|:|:||..:..|||||||||||||||.::.| :.:|   ||:
 Worm   356 TDVHEIVLVGGSTRIPKVQQLIKDYFNGKEPSRGINPDEAVAYGAAVQAGVIGGVENTG---DVV 417

  Fly   391 LVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALG 455
            |:||.||:|||||.||||||||.||..||.|:::.|||.||:|..|||.:|||||.|..||:.||
 Worm   418 LLDVNPLTLGIETVGGVMTKLIGRNTVIPTKKSQVFSTAADSQSAVSIVIYEGERPMVMDNHKLG 482

  Fly   456 TFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEA 520
            .||::||||||||||||||||::|.||||:|||::..||....:||.||..|||..:|:||:|:|
 Worm   483 NFDVTGIPPAPRGVPQIEVTFEIDVNGILHVSAEDKGTGNKNKLTITNDHNRLSPEDIERMINDA 547

  Fly   521 EKYADEDEKHRQRITSRNALESYVFNVKQAV--EQAPAGKLDEADKNSVLDKCNDTIRWLDSNTT 583
            :|:|.:|:..::::.|||.||:|.:.:|..:  ::...|||.:.||.|:.......|.||.||..
 Worm   548 DKFAADDQAQKEKVESRNELEAYAYQMKTQIADKEKLGGKLTDEDKVSIESAVERAIEWLGSNQD 612

  Fly   584 AEKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQ 626
            |..||...:.:||.....||::|::      .|||.|....::
 Worm   613 ASTEENKEQKKELESVVQPIVSKLY------SAGGQGEQASEE 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	362/628 (58%)
hsp-4	NP_001370395.1	PTZ00009	33..643	CDD:240227	361/620 (58%)