Protein Alignment Hsp70Ab and hsp-70

DIOPT Version :9

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_492485.1
• Gene: hsp-70 / 172757
• WormBaseID: WBGene00002026
• Length: 643
• Species: Caenorhabditis elegans
• Alignment Length: 645
• Identity: 449/645 - (69%)
• Similarity: 531/645 - (82%)
• Gaps: 12/645 - (1%)

  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67
            ||||||||||||||:||:|||||:||.:||:||||||||||:|||:||.||:|.|.||.||||||
 Worm     6 AIGIDLGTTYSCVGIYQNGKVEILANSEGNKTTPSYVAFTDTERLVGDAAKDQAARNPENTVFDA 70

  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132
            ||||||::|:..:..|:|||||.|....|||.:.||.|||.:.|..||||:|||.||||||||.|
 Worm    71 KRLIGRRFDEETVQSDIKHWPFTVKGKQGKPVVEVEVKGEKREFNAEEISAMVLQKMKETAEAVL 135

  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197
            |.|:.|||||||||||||||||||||..|||||.:|||||||||||||||||.:..|:|:|||||
 Worm   136 GHSVRDAVITVPAYFNDSQRQATKDAATIAGLNAIRIINEPTAAALAYGLDKGITDEKNILIFDL 200

  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALRRLR 262
            ||||||||||:|.|||:|||:||||||||||||||:|::.|...|||||..||:.|||||:||||
 Worm   201 GGGTFDVSILSIAEGSIFEVKSTAGDTHLGGEDFDSRVLQHFMTEFKRKTGKDISSNPRAIRRLR 265

  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327
            ||.||||||||||||||:|:|:||:|.|||:|::|||||||||||||.||:||||||.|||.|||
 Worm   266 TACERAKRTLSSSTEATVEVDSLFDGTDFYSKITRARFEELCADLFRKTLEPVEKALRDAKTDKG 330

  Fly   328 QIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392
            :|.::|||||||||||:|.||::||:||:||.|||||||||:|||||||:|||.:...|:|||||
 Worm   331 RIDEVVLVGGSTRIPKIQKLLKEFFNGKDLNCSINPDEAVAFGAAVQAAVLSGVKDDTIKDVLLV 395

  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNALGTF 457
            ||.|||.||||||||||.||:||.|||.|.:|||:|||||||||||||||||||||:||:.||||
 Worm   396 DVVPLSHGIETAGGVMTNLIDRNTRIPAKASKTFTTYADNQPGVSIQVYEGERAMTRDNHRLGTF 460

  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522
            :|:|||||||||||::||||:||||||||||.:.|||::..|||:|:|||||||:||||||||::
 Worm   461 ELTGIPPAPRGVPQVDVTFDIDANGILNVSAADKSTGRSNRITIRNEKGRLSQADIDRMVNEAKQ 525

  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQAVEQAPAGKLDEADKNSVLDKCNDTIRWLDSNTTAEKE 587
            :..||...|.||:|||.||:|.|.||||:|: ....|...|.....|...||:||::.||.|:|:
 Worm   526 FEREDAAQRDRISSRNQLEAYAFQVKQALEE-HGSLLSAEDAKRAKDAVEDTLRWMERNTLADKD 589

  Fly   588 EFDHKLEELTRHCSPIMTKMHQQGA--GAGAGGPGANCGQQAGGF--GGY-SGPTVEEVD 642
            |.:.|.:||...|..|:||||||.|  |:|.|.||      :|||  ..| .||||||||
 Worm   590 EIEAKDKELKSICQDILTKMHQQEAQSGSGCGNPG------SGGFHSSNYPQGPTVEEVD 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	447/643 (70%)
		HSPA1-2_6-8-like_NBD	3..379	CDD:212675	281/375 (75%)
hsp-70	NP_492485.1	PTZ00009	1..643	CDD:240227	447/643 (70%)
		HSPA1-2_6-8-like_NBD	6..382	CDD:212675	281/375 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53894
OrthoDB	1	1.010	-	-		D180577at33208
OrthoFinder	1	1.000	-	-		FOG0000049
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100083
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.730