Protein Alignment Hsp70Ab and hspa2

DIOPT Version :10

• Sequence 1: NP_524798.2
• Gene: Hsp70Ab / 44920
• FlyBaseID: FBgn0013276
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_004917261.1
• Gene: hspa2 / 100496396
• XenbaseID: XB-GENE-992125
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 644
• Identity: 466/644 - (72%)
• Similarity: 543/644 - (84%)
• Gaps: 19/644 - (2%)

  Fly     2 PAIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFD 66
            ||:|||||||||||||:||||||||||:||||||||||||||:||||||.||||||:||.||:||
 Frog     6 PAVGIDLGTTYSCVGVFQHGKVEIIANEQGNRTTPSYVAFTDTERLIGDAAKNQVALNPANTIFD 70

  Fly    67 AKRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAY 131
            |||||||::|||.:..|||||||.|||||||||:.||:|||:|.|.|||||||||:||||.||||
 Frog    71 AKRLIGRRFDDPTVQADMKHWPFTVVSDGGKPKVKVEFKGENKTFFPEEISSMVLSKMKEVAEAY 135

  Fly   132 LGESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKN--LKGERNVLI 194
            ||..:.:|||||||||||||||||||||.|:|:|||||||||||||:||||||.  ..||.||||
 Frog   136 LGVKVPNAVITVPAYFNDSQRQATKDAGVISGINVLRIINEPTAAAIAYGLDKKGAGHGETNVLI 200

  Fly   195 FDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLADEFKRKYKKDLRSNPRALR 259
            |||||||||||:|||| |.:|||:||||||||||||||||:|.|..:|||||.|||:..|.||:|
 Frog   201 FDLGGGTFDVSVLTID-GGIFEVKSTAGDTHLGGEDFDNRMVAHFVEEFKRKNKKDISGNKRAVR 264

  Fly   260 RLRTAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKM 324
            |||||.|||||||||||:|::|||:|:||.||||.::|||||||||||||.||:||||||.|||:
 Frog   265 RLRTACERAKRTLSSSTQASLEIDSLYEGADFYTAITRARFEELCADLFRGTLEPVEKALRDAKL 329

  Fly   325 DKGQIHDIVLVGGSTRIPKVQSLLQDFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDV 389
            ||.||.:||||||||||||||.||||||:|:.||.||||||||||||||||||||||:|..:||:
 Frog   330 DKAQIREIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILSGDKSHNVQDL 394

  Fly   390 LLVDVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYADNQPGVSIQVYEGERAMTKDNNAL 454
            ||:|||||||||||||||||.||:||..||.|||:||:||:|||..|.:||||||||||:|||.|
 Frog   395 LLLDVAPLSLGIETAGGVMTALIKRNTTIPSKQTQTFTTYSDNQSSVLVQVYEGERAMTRDNNLL 459

  Fly   455 GTFDLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNE 519
            |.|||:|||||||||||||||||:||||||||:|.:.||||...|||.|||||||:.:|:||||:
 Frog   460 GKFDLTGIPPAPRGVPQIEVTFDIDANGILNVTAADKSTGKENKITITNDKGRLSKEDIERMVND 524

  Fly   520 AEKYADEDEKHRQRITSRNALESYVFNVKQAVE-QAPAGKLDEADKNSVLDKCNDTIRWLDSNTT 583
            ||||..|||.:|.|:.::|.||||.:::||..| :...|||.|.:|:.:||||.:.|.||:.|..
 Frog   525 AEKYKAEDELNRDRVAAKNGLESYAYHIKQTAEDEKLKGKLSEKEKSQILDKCKEVIDWLEKNQM 589

  Fly   584 AEKEEFDHKLEELTRHCSPIMTKMHQQGAGAGAGGPGANCGQQAGGFGGYSGPTVEEVD 642
            |||:||:||.:||.:.|:||:||::|    .||..||.     ||      |||:||||
 Frog   590 AEKDEFEHKQKELEKVCNPIITKLYQ----GGAPNPGT-----AG------GPTIEEVD 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp70Ab	NP_524798.2	PTZ00009	2..642	CDD:240227	464/642 (72%)
hspa2	XP_004917261.1	PTZ00009	2..633	CDD:240227	464/642 (72%)