DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DNApol-alpha60 and EMB2813

DIOPT Version :9

Sequence 1:	NP_652001.2	Gene:	DNApol-alpha60 / 44915	FlyBaseID:	FBgn0259676	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_001185339.1	Gene:	EMB2813 / 843052	AraportID:	AT1G67320	Length:	490	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	182/499 - (36%)
Similarity:	270/499 - (54%)	Gaps:	76/499 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RHEVKVEVASLETKYPHNVMLYHYPPTEDVHIDEFEELALERLRLLR-VLD-RASTRNLRVLSD- 71
            :..|..:|.|..|     :.||...|..:|.::|||..|::|||:|: |.| .|..||...:.|
plant     8 KRTVSNDVVSTPT-----LPLYLTAPHMEVRLEEFELFAIDRLRVLKGVSDGLARARNPNEMDDL 67

  Fly    72 ---EWKEIVSADLTREGLRSYLRLCSTGGSAKHEADIQTRRRDYLSHFILRLAYCRSEDLARWFV 133
               .|||             ::||.:..         :...:|.:|||:|||.||||::|.:||:
plant    68 VETLWKE-------------HMRLSNVS---------EMINKDIISHFVLRLVYCRSDELKKWFL 110

  Fly   134 AREMELFRYKFAALSSFEVKQFLEANGFEIHPLTEAQKDEVKD--GLYESTVGQ----------- 185
            :.|..|||::|......|.:..:...|.....:..|:.:.:|:  ||...:.||
plant   111 SMETALFRHRFRLKKIEEQRAIVGEFGLPYKAVIGAELESLKERLGLVARSHGQISSDGTCNMLY 175

  Fly   186 -------SVAKIELLDF-----------------YKVPFTQVLDLVRGRRCFLKAGYAYVNTHDL 226
                   |...::|:.|                 |||||.:|.|||..||..|:.|:|:|....|
plant   176 FDPMFTLSHLAVKLVPFLMEKFLSFLSFAVENIYYKVPFEEVPDLVASRRVLLQKGFAFVAGTQL 240

  Fly   227 VSLVGTKQQDEIEQGL----QAAKTMVEDVEADERISRTLKALHNSYTGRDYTVCRD-AAVPIES 286
            ||||.|:.:..:.:.|    :...|.:.:.|.| |::..::||..||.|.||:...: |.:.::.
plant   241 VSLVVTQFRSHLSKALILTNRKWTTTIREREKD-RLTPIVEALSTSYLGPDYSQSNEYADISLKD 304

  Fly   287 LDQLSKTSMPLCMRMCHEHIRANHHIKHSGRMQYGLFLKGIGVALEDSLRFWREEFTKKMDADKF 351
            :||:||:|.|||||...|.:|.:||:||.||||.||||||:|:.|:|:|.|||||||||:.:::|
plant   305 IDQVSKSSFPLCMRHLFEKLREDHHLKHGGRMQLGLFLKGVGLKLDDALAFWREEFTKKVGSERF 369

  Fly   352 TRSYEYNIYHNYGKKGSMVNYTPYSCAKIIKDVAGPGDCHGCPYKNMDQGSLKTKLSSYGLSASA 416
            .:.|.|.|.|||||:|...:||||:|:|||....|.||.|||||::..:.:||..||..|||:..
plant   370 DKEYAYAIRHNYGKEGKRTDYTPYACSKIITSAPGAGDHHGCPYRHFSEDNLKAALSRMGLSSRG 434

  Fly   417 IDEVMFFVSRGHYQIGCGKYFQLTHNSPVEPSINHPNNYFEESQ 460
            :::||..|...|||:.|...|:..:.:..:..|||||.||||||
plant   435 MEDVMDKVRNRHYQLACTLTFEAVYGTSCDTGINHPNQYFEESQ 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-alpha60	NP_652001.2	PriL_PriS_Eukaryotic	30..459	CDD:143474	175/476 (37%)
EMB2813	NP_001185339.1	PriL_PriS_Eukaryotic	23..477	CDD:143474	175/476 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	248	1.000	Domainoid score	I535
eggNOG	1	0.900	-	-		E1_COG2219
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H731
Inparanoid	1	1.050	313	1.000	Inparanoid score	I734
OMA	1	1.010	-	-		QHG53502
OrthoDB	1	1.010	-	-		D479347at2759
OrthoFinder	1	1.000	-	-		FOG0005104
OrthoInspector	1	1.000	-	-		oto3112
orthoMCL	1	0.900	-	-		OOG6_102391
Panther	1	1.100	-	-	LDO	PTHR10537
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3626
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840