Protein Alignment DNApol-alpha60 and Prim2

DIOPT Version :9

• Sequence 1: NP_652001.2
• Gene: DNApol-alpha60 / 44915
• FlyBaseID: FBgn0259676
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: XP_006244748.1
• Gene: Prim2 / 301323
• RGDID: 631433
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 520
• Identity: 194/520 - (37%)
• Similarity: 302/520 - (58%)
• Gaps: 45/520 - (8%)

  Fly     1 MEFGLKKRARHEVKVEVASLETKYPHNVMLYHYPPTEDVHIDEFEELALERLRLLRVLDRASTRN 65
            |:|  ..|.|.::::........|||::..|..||||::.:.|||.||.:|::||:.::     |
  Rat     1 MQF--SGRTRKKLRLAGDQRNACYPHSLQFYLQPPTENISLTEFESLAFDRVKLLKAIE-----N 58

  Fly    66 LRVL----SDEWKEIVSADLT------REGLRSYLRLCSTGGSAKHEADIQTRRRDYLSHFILRL 120
            |.|.    :::::..:.|::.      ||.|               |.:.:.||||::|||||||
  Rat    59 LGVSYVKGTEQYQSKLEAEIRKLKFSYRENL---------------EDEYEPRRRDHISHFILRL 108

  Fly   121 AYCRSEDLARWFVAREMELFRYKFAALSSFEVKQFLEANGFEIHPLTEAQKDEVKDGLYESTVGQ 185
            |||:||||.|||:.:||:|.|::|:.|...:|:.||:........:::.:|...:..:..|:...
  Rat   109 AYCQSEDLRRWFIQQEMDLLRFRFSILPKDKVQSFLKDTHLHFEAISDEEKTLREQDIMASSPSL 173

  Fly   186 SVAKIELLDFYKVPFTQVLDLVRGRRCFLKAGYAYVNTHDLVSLVGTKQQDEIEQGLQAAKTMVE 250
            |..:.|....|||||...|||.|||:.:|:.|:|||...|:|:::..:.:..:.:.|......:.
  Rat   174 SGVRWESESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRATLSKALALTARSLP 238

  Fly   251 DVEADERISRTLKALHNSYTGRDYTVCRDAA-VPIESLDQLSKTSMPLCMRMCHEHIRANHHIKH 314
            .|::|||:...|..|.:||||:||:..:... :.::.:|.||..|.|.|||..|:.:|.|||::|
  Rat   239 AVQSDERLQPLLSHLSHSYTGQDYSTQKSTGKISLDQIDSLSTKSFPPCMRQLHKALRENHHLRH 303

  Fly   315 SGRMQYGLFLKGIGVALEDSLRFWREEFTK-KMDADKFTRSYEYNIYHNYGKKGSMVNYTPYSCA 378
            .|||||||||||||:.||.:|:||::||.| |||.|||.:.|.|||.|::||:|...:|||:||.
  Rat   304 GGRMQYGLFLKGIGLTLEQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCM 368

  Fly   379 KIIKDVAGP---GDCHGCPYKNMDQGSLKTKLSSYGLSASAIDEVMFFVSRGHYQIGCGKYFQLT 440
            |||  :..|   ||.||||:::.|...||.|:.:|.:.||.|.:::..|...|||:.|.|||::|
  Rat   369 KII--LTNPPSQGDFHGCPFRHSDAELLKQKMQTYKIPASGISQILDLVKGNHYQVACQKYFEMT 431

  Fly   441 HNSPVEP---SINHPNNYFEESQ-IAMGNRQKRANGSAPPKARIRPDIKGHGDRSMLMGDDDDEL 501
            ||  |:.   |:||||.:|.||| |..|.:..:...|.|...:.:|..:...|.:..:...|..|
  Rat   432 HN--VDDCGFSLNHPNQFFFESQRILTGGKDIKKEASHPETPQHKPSTQKTKDATSALASLDSSL 494

  Fly   502  501
              Rat   495  494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNApol-alpha60	NP_652001.2	PriL_PriS_Eukaryotic	30..459	CDD:143474	176/446 (39%)
Prim2	XP_006244748.1	PriL_PriS_Eukaryotic	28..451	CDD:143474	176/446 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353757
Domainoid	1	1.000	253	1.000	Domainoid score	I2010
eggNOG	1	0.900	-	-		E1_COG2219
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H731
Inparanoid	1	1.050	361	1.000	Inparanoid score	I2131
OMA	1	1.010	-	-		QHG53502
OrthoDB	1	1.010	-	-		D222812at33208
OrthoFinder	1	1.000	-	-		FOG0005104
OrthoInspector	1	1.000	-	-		oto97993
orthoMCL	1	0.900	-	-		OOG6_102391
Panther	1	1.100	-	-	LDO	PTHR10537
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3626
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770