DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Acam and calb2b

DIOPT Version :9

Sequence 1:	NP_001163737.1	Gene:	Acam / 44913	FlyBaseID:	FBgn0011273	Length:	148	Species:	Drosophila melanogaster
Sequence 2:	NP_957005.1	Gene:	calb2b / 393684	ZFINID:	ZDB-GENE-040426-1668	Length:	269	Species:	Danio rerio

Alignment Length:	176	Identity:	43/176 - (24%)
Similarity:	79/176 - (44%)	Gaps:	41/176 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTL-----GQNPTEAELQDLIAE----AE 56
            ::|||..|   |.|.:.:||.:|.|.|..:||...:|.|     ..:|:.|..:|.:.|    .:
Zfish    13 LAELTASQ---FLDIWNKFDADGNGCIEGKELENFIRELEIARKTADPSNASFKDRMKEFMQKFD 74

  Fly    57 NNNNGQLNFTEFCGIMAKQMRETDTEE--------------EMREAFKIFDRDGDGFISPAELRF 107
            .|.:|::..:|...|:       .|||              |...|::.:|.|..|:|...||:.
Zfish    75 ENGDGKIEMSELAQIL-------PTEENFLLCFRQFVGSSAEFMTAWRKYDTDRSGYIESNELKG 132

  Fly   108 VMINLGEKV----TDEEIDE----MIREADFDGDGMINYEEFVWMI 145
            .:.:|.:|.    .|::::|    :::..|.:|||.:...|...::
Zfish   133 FLSDLLKKANRHYNDKKLNEYTQTILKMFDLNGDGKLGLSEMARLL 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Acam	NP_001163737.1	PTZ00184	3..148	CDD:185504	43/174 (25%)
		EFh	11..73	CDD:238008	19/70 (27%)
		EFh	84..146	CDD:238008	17/70 (24%)
calb2b	NP_957005.1	PTZ00184	13..178	CDD:185504	43/174 (25%)
		EFh	20..90	CDD:238008	19/72 (26%)
		EFh	109..178	CDD:238008	17/68 (25%)
		EF-hand_7	155..218	CDD:290234	5/24 (21%)
		EFh	157..223	CDD:238008	5/22 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910