Protein Alignment unc-45 and Sgta

DIOPT Version :10

• Sequence 1: NP_524796.1
• Gene: unc-45 / 44910
• FlyBaseID: FBgn0288846
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: XP_006241058.3
• Gene: Sgta / 64667
• RGDID: 620815
• Length: 369
• Species: Rattus norvegicus
• Alignment Length: 206
• Identity: 64/206 - (31%)
• Similarity: 88/206 - (42%)
• Gaps: 41/206 - (19%)

  Fly     6 NSEEVSDAGSYKDKGNEAFKASRWEEAVEHYGKAIKAGSKHKELAVFYKNRAAAYLKLGKYENAV 70
            :.|:.::|...|.:|||..|...:|.||..|||||:....:   ||::.||||||.|||.|..||
  Rat   139 SEEDSAEAERLKTEGNEQMKLENFEAAVHLYGKAIELNPAN---AVYFCNRAAAYSKLGNYVGAV 200

  Fly    71 EDCTESLKAAPGDPKALFRRAQAYEALEKFEEA---YKDATALFKADPGNKTVQPMLQRLHVVVE 132
            :||..::...||..||..|...|..:|.|..||   ||.|..|   ||.|.|.:..|:     :.
  Rat   201 QDCERAIGIDPGYSKAYGRMGLALSSLNKHAEAVAYYKKALEL---DPDNDTYKSNLK-----IA 257

  Fly   133 ERSARNAKTSTKVKQMMDLTFDLATPIDKRRAAANNLVVLAKEQTGAELLYKDHCIAKVASLTKV 197
            |...|.|.:.|.....:|:                           |.||...|.|...:||...
  Rat   258 ELKLREAPSPTGGVGSLDI---------------------------AGLLNNPHFITMASSLMNS 295

  Fly   198 EKDQDIYVNMV 208
            .:.|.:...|:
  Rat   296 PQLQQLMSGMI 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
unc-45	NP_524796.1	3a0801s09	7..>127	CDD:273380	50/122 (41%)
		TPR repeat	16..41	CDD:276809	12/24 (50%)
		TPR repeat	46..79	CDD:276809	16/32 (50%)
		UNC45-central	351..494	CDD:432011
		PLN03200	399..>700	CDD:215629
		armadillo repeat	753..789	CDD:293788
		armadillo repeat	795..826	CDD:293788
Sgta	XP_006241058.3	SGTA_dimer	59..118	CDD:465168
		TPR	140..>261	CDD:440225	51/131 (39%)
		TPR repeat	146..174	CDD:276809	13/27 (48%)
		TPR repeat	179..209	CDD:276809	16/32 (50%)
		TPR repeat	214..242	CDD:276809	11/27 (41%)