DRSC/TRiP Functional Genomics Resources

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Protein Alignment unc-45 and Sugt1

DIOPT Version :9

Sequence 1:NP_001303425.1 Gene:unc-45 / 44910 FlyBaseID:FBgn0010812 Length:947 Species:Drosophila melanogaster
Sequence 2:NP_001013069.1 Gene:Sugt1 / 290408 RGDID:1307550 Length:336 Species:Rattus norvegicus


Alignment Length:218 Identity:46/218 - (21%)
Similarity:88/218 - (40%) Gaps:34/218 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    30 EEAVEHYGKAIKAGSKHKELAVFYKNRAAAYLKLGKYENAVEDCTESLKAAPGDPKALFRR--AQ 92
            :.|:|...||::   ::.:.|.:|..||..::.||||.:.:.|..:||:..|.:..||.|:  .:
  Rat    28 QAALEELTKALE---QNPDDAQYYCQRAYCHILLGKYCDGIADVKKSLELNPNNSTALLRKGICE 89

  Fly    93 AYE-----ALEKFEEAYK-DATALFKADPGNKTVQPMLQRLHVVVEERSARNAKTSTKVKQMMDL 151
            .||     |||.|.|..| |.|     |..........|.:....|...:.:.:|.:|:|     
  Rat    90 YYEKDYASALETFAEGQKLDGT-----DTNFDIWIKRCQEIQNGSEPEVSASQRTQSKIK----- 144

  Fly   152 TFDLATPIDKRRAAANNLVVLAKEQTGAELLYKDHCIAKVASLTKVEKDQDIYVNMVHLVAALCE 216
                   .|..:..::.::.|..:......:..|....:::::.|:...:|..:.:..|...:.|
  Rat   145 -------YDWYQTESHVIITLMIKNVQKNDVRVDFSEKELSAVVKIPSGEDCSLKLRLLHPIIPE 202

  Fly   217 NSVERTKGVLTEL------GVPW 233
            .|..:......|:      .|.|
  Rat   203 QSTFKVLSTKIEIKMKKPEAVRW 225

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
unc-45NP_001303425.1 TPR_11 12..81 CDD:290150 15/50 (30%)
TPR repeat 16..41 CDD:276809 4/10 (40%)
TPR repeat 46..79 CDD:276809 11/32 (34%)
TPR_11 50..115 CDD:290150 25/72 (35%)
TPR 50..83 CDD:197478 12/32 (38%)
UNC45-central 351..494 CDD:288539
ARM 668..788 CDD:237987
armadillo repeat 753..789 CDD:293788
armadillo repeat 795..826 CDD:293788
Sugt1NP_001013069.1 TPR 1 11..44 4/18 (22%)
PLN03088 21..336 CDD:215568 46/218 (21%)
TPR repeat 44..74 CDD:276809 11/29 (38%)
TPR 2 45..78 12/32 (38%)
TPR 45..78 CDD:197478 12/32 (38%)
TPR 3 79..112 13/37 (35%)
TPR repeat 79..107 CDD:276809 10/27 (37%)
p23_CS_hSgt1_like 146..229 CDD:107239 11/80 (14%)
SGS 256..336 CDD:282811
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166349602
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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