DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Larp7 and LARP6b

DIOPT Version :9

Sequence 1:	NP_524795.2	Gene:	Larp7 / 44900	FlyBaseID:	FBgn0260771	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_566004.1	Gene:	LARP6b / 819002	AraportID:	AT2G43970	Length:	545	Species:	Arabidopsis thaliana

Alignment Length:	459	Identity:	105/459 - (22%)
Similarity:	170/459 - (37%)	Gaps:	111/459 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EKEKGEGQEPATSAEKPDPAAPTEPAEENSKEPAPED--------ASPDKKDGGRKRKRHLFNSI 63
            ::..|.|.|     ::||..:......::||..:..|        .|.|.|.|   ........|
plant   141 QQRGGVGGE-----QEPDLVSKKNDRRDHSKRESKNDQVTETGASVSIDSKTG---LPEDSIQKI 197

  Fly    64 RGQMEFYFGDANLSKDRFLRRYVEQDP--YVPLEIFLTFNKIKTLTQDVQQIAKALSNSQLLELD 126
            ..|:|:||.|.||:....|.|::.:||  |||:.:..:|.|||.:..:..|:|..|.||..|.:.
plant   198 VNQVEYYFSDLNLATTDHLMRFICKDPEGYVPIHVVASFKKIKAVINNNSQLAAVLQNSAKLFVS 262

  Fly   127 ETELKVKRRTKLPDQ--RDVNDKTLYVEALPANATHDWLKEVFSRYG-----------------P 172
            |...||:|.:.:.:.  .::..:.:..|.||.:..:..|.::||..|                 |
plant   263 EDGKKVRRISPITESAIEELQSRIIVAENLPEDHCYQNLMKIFSTVGSVKNIRTCQPQNNGSGAP 327

  Fly   173 VAYVSLPHYPGTK-KIKEFAFIEFEKSGSLEKAVKAFAQIQGVLSVETDPSDLASVRSFQQQQQI 236
            .|..|.....||. ..|..||:|:|.....|:||             |:.|:..:.||..:.:.:
plant   328 PAARSAAKSDGTLFSNKVHAFVEYEIVELAERAV-------------TELSEAGNWRSGLKVRLM 379

  Fly   237 QQKAEQPQSEAEQVELPKRNLKREATDKDREEIHEVKRVKLEEGQPSETSTAGETASETDAEGTA 301
            .:         .|.:.||:...|.....|.:..||.......|.||.|..:       .|..|..
plant   380 LK---------HQTKEPKQGQGRGRKGHDADVEHEEDDATTSEQQPIEKQS-------DDCSGEW 428

  Fly   302 EASEQEDKTEATDGDEAAKKRRRKRKKKAIVDKPNIEPSALELKVLPKTSWSSMRNKYLNLQRRI 366
            :...||.......|:|.|..:|:.|.:.....:...:|.               :|:..|
plant   429 DTHMQEQPIGEDQGNEKAAGQRKGRNRGRGKGRGRGQPH---------------QNQNQN----- 473

  Fly   367 VSEAKSKLWRENHPQNQQHPHHQQTSHPNH------PKPS-------QLPEAVKEEETGGEVPSD 418
                      .||..||.|.|:.:.:|.:|      .:||       :.|...|::..|..:| |
plant   474 ----------NNHSHNQNHNHNGRGNHHHHHHHQVGTQPSNNPMNNMEQPGMGKQQPPGPRMP-D 527

  Fly   419 GGEG 422
            |..|
plant   528 GTRG 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Larp7	NP_524795.2	LA	57..135	CDD:128955	28/79 (35%)
		RRM	<116..>208	CDD:223796	28/111 (25%)
		RRM1_LARP7	148..>209	CDD:240736	20/78 (26%)
		RRM2_LARP7	471..548	CDD:240986
LARP6b	NP_566004.1	LARP_6	194..270	CDD:153402	28/75 (37%)
LARP6b	NP_566004.1	RRM_La_like_plant	285..380	CDD:240734	24/107 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2379
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3115
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960