DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Larp7 and larp

DIOPT Version :9

Sequence 1:	NP_524795.2	Gene:	Larp7 / 44900	FlyBaseID:	FBgn0260771	Length:	595	Species:	Drosophila melanogaster
Sequence 2:	NP_001247347.1	Gene:	larp / 53567	FlyBaseID:	FBgn0261618	Length:	1673	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	84/430 - (19%)
Similarity:	147/430 - (34%)	Gaps:	112/430 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 SIRGQMEFYFGDANLSKDRFLRRYVEQDPYVPLEIFLTFNKIKTLTQDVQQIAKALSNSQLLELD 126
            :|:.|:|:||...||:.|.||||.::.:.|:|:.:..:|:::..||.||..|..|:..|..|||.
  Fly   732 AIKKQVEYYFSVDNLTGDFFLRRKMDPEGYIPVTLIASFHRVLALTTDVAVIVNAIKESDKLELF 796

  Fly   127 ETELKVKRR--------TKLPDQRDVNDKTLYVEALPANATHDWLKEVFSRYGPVAYVSLPHYPG 183
            | ..||:.:        |::|:..:...|.:                     |.:....|....|
  Fly   797 E-GYKVRTKTTPTTWPITEVPEVNEGEPKAI---------------------GTLEQEQLEQNDG 839

  Fly   184 TKKIKEFAFIEFEKSGSLEKAVKAFAQIQGVLSVETD--PSDLASVRSFQQQQQIQQKAEQPQSE 246
            .:|::|                          ..|.|  |..|.|..:.:....|   ...|...
  Fly   840 QEKLEE--------------------------QTEADSPPPILTSAMATKPLNSI---PPPPMPR 875

  Fly   247 AEQVELPK----RNLKREATDKDREEIHEVKRVKLE-EGQPSETSTAGETASETDAEGTAEASEQ 306
            ..|..:||    :...|.:|......::.:..:..: ||..:|  .||..:...::......|..
  Fly   876 NPQNLVPKMLQDKQQSRSSTIAALNSVNAISALTQQVEGGAAE--LAGHLSGLAESVKPKSTSTP 938

  Fly   307 EDKTEATDGDEAAKKRRRKRKKKAIVDKPNIEPSALELKVLPKTSWSSMRNKYLNLQRRIVSEAK 371
            :.:..|:.|:.|.                    ||..|...|:..|..::.:           :|
  Fly   939 DKRNAASAGNGAG--------------------SAAALVAEPEGIWKEVKRR-----------SK 972

  Fly   372 SKLWREN--HPQNQQHPHHQQTSHPNHPKPSQLPEAVKEEETGGEVPSDGGEGAVEAAPV--PAK 432
            :...:||  .|..||.|...||.:.|:........:.|.:.:....||:....|......  .:.
  Fly   973 TNAIKENATTPPQQQQPPLSQTLNNNNDNVKTNNTSSKSKSSSNNAPSNASSSATVCVTTNNASS 1037

  Fly   433 RRKAVHKMNM---------NFYGAGGVESTKSEEPSQERT 463
            ..||..|...         |...:|....:|:...|..:|
  Fly  1038 ATKATTKTTTTSTATTTTNNNIKSGNAAYSKTHSKSSSKT 1077

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Larp7	NP_524795.2	LA	57..135	CDD:128955	28/72 (39%)
		RRM	<116..>208	CDD:223796	16/99 (16%)
		RRM1_LARP7	148..>209	CDD:240736	5/60 (8%)
		RRM2_LARP7	471..548	CDD:240986
larp	NP_001247347.1	LARP_1_2	730..803	CDD:153403	28/71 (39%)
		DM15	1341..1382	CDD:128927
		DM15	1383..1421	CDD:128927
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456175
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22792
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940