Protein Alignment Larp7 and LARP7

DIOPT Version :10

• Sequence 1: NP_524795.2
• Gene: Larp7 / 44900
• FlyBaseID: FBgn0260771
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_001357903.1
• Gene: LARP7 / 51574
• HGNCID: 24912
• Length: 595
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 175/647 - (27%)
• Similarity: 285/647 - (44%)
• Gaps: 148/647 - (22%)

  Fly    33 EENSKEPAPEDASPDKKDGGRKRKR----HLFNSIRGQMEFYFGDANLSKDRFLRRYVE--QDPY 91
            |..::|...|:.|.:||....|:||    .:...|..|::|:||||||.||||||..:|  :|.|
Human     4 ESGNQEKVMEEESTEKKKEVEKKKRSRVKQVLADIAKQVDFWFGDANLHKDRFLREQIEKSRDGY 68

  Fly    92 VPLEIFLTFNKIKTLTQDVQQIAKALSNSQLLELDETELKVKRRTKLPDQ-RDVNDKTLYVEALP 155
            |.:.:.::|||:|.||.|.:.||:||.:|.::|||....:::|:..|.:: :|.:::|:|||.||
Human    69 VDISLLVSFNKMKKLTTDGKLIARALRSSAVVELDLEGTRIRRKKPLGERPKDEDERTVYVELLP 133

  Fly   156 ANATHDWLKEVFSRYGPVAYVSLPHYPGTKKIKEFAFIEFE---------------------KSG 199
            .|..|.|::.||.:.|.|.|:|:|||..|...|.|||:|||                     |.|
Human   134 KNVNHSWIERVFGKCGNVVYISIPHYKSTGDPKGFAFVEFETKEQAAKAIEFLNNPPEEAPRKPG 198

  Fly   200 SLEKAVKAFAQIQGVLSVETDPSDLASVRSFQQQQQIQQKAE---------------QPQSEAEQ 249
            ...|.||. ..|..:..||............:::..||.|.|               :|.||...
Human   199 IFPKTVKN-KPIPALRVVEEKKKKKKKKGRMKKEDNIQAKEENMDTSNTSISKMKRSRPTSEGSD 262

  Fly   250 VEL--PKRNLKREATDKDREEIHEVKRVKLEEGQPSETSTAG-----------------ETASET 295
            :|.  |::...::...:||.|...:..|:..:.:.|.:..|.                 :.|||.
Human   263 IESTEPQKQCSKKKKKRDRVEASSLPEVRTGKRKRSSSEDAESLAPRSKVKKIIQKDIIKEASEA 327

  Fly   296 DAEGTA--------------EASEQEDKTEATDGDEAAKKRRRKRKKKAIVDKPNIEPSALELKV 346
            ..|..|              |.|.:|:|......|.:..|.:||.|||. .::..:....:.|:|
Human   328 SKENRAPCLNGELFYLFQDIEISTEEEKDTGDLKDSSLLKTKRKHKKKH-KERHKMGEEVIPLRV 391

  Fly   347 LPKTSWSSMRNKYLNLQRRIVSEAKSKLWRENHPQNQQHPHHQQTSHPNHPKPSQLPEAVKEEET 411
            |.|:.|..::.:||.||:..::..|..:                         ||: ::..|.||
Human   392 LSKSEWMDLKKEYLALQKASMASLKKTI-------------------------SQI-KSESEMET 430

  Fly   412 GGEVPSDGGEGAVEAAPVPAKRRKAVHKMNMNFYGAGGVESTKSEEPSQERTPLFKYEPGLIVEC 476
            ...||.:.|          .|..|..::           |..:::|......|  ::..|:||:.
Human   431 DSGVPQNTG----------MKNEKTANR-----------EECRTQEKVNATGP--QFVSGVIVKI 472

  Fly   477 SLLKPCTNVKEFKAEMRQYPDIKYVDIKEGDQVALLRLGTPAAAEELLR---QVN---CSERQLK 535
            ...:|....|:.:..:....::.|||:.|||.....|..||..|:.::.   ::|   |  .:|:
Human   473 ISTEPLPGRKQVRDTLAAISEVLYVDLLEGDTECHARFKTPEDAQAVINAYTEINKKHC--WKLE 535

  Fly   536 VLSGQQETLYWRKIEQDREAKLSKKVRVQQKRGREKV-----------GKMLGKHIKFDDGD 586
            :|||..|..||:||..||:|||::.  .::|||.||:           .:...|||:|.:.|
Human   536 ILSGDHEQRYWQKILVDRQAKLNQP--REKKRGTEKLITKAEKIRLAKTQQASKHIRFSEYD 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Larp7	NP_524795.2	LA	57..135	CDD:128955	35/83 (42%)
		RRM1_LARP7	148..220	CDD:409732	34/92 (37%)
		RRM2_LARP7	471..548	CDD:409958	24/82 (29%)
LARP7	NP_001357903.1	LARP_7	30..111	CDD:153401	34/80 (43%)
		RRM1_LARP7	126..205	CDD:409732	29/78 (37%)
		RRM2_LARP7	467..548	CDD:409958	24/82 (29%)