Protein Alignment Larp7 and larp4

DIOPT Version :10

• Sequence 1: NP_524795.2
• Gene: Larp7 / 44900
• FlyBaseID: FBgn0260771
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_001135708.1
• Gene: larp4 / 100216284
• XenbaseID: XB-GENE-951123
• Length: 734
• Species: Xenopus tropicalis
• Alignment Length: 675
• Identity: 135/675 - (20%)
• Similarity: 217/675 - (32%)
• Gaps: 203/675 - (30%)

  Fly    39 PAPEDASPDKKDGGRKRKRHLFNSIRGQMEFYFGDANLSKDRFLRRYVEQDPYVPLEIFLTFNKI 103
            |.|:..|.:          .|...::.|:||.|...|||||.:|...::.|.:||:........|
 Frog   113 PVPQVVSAE----------DLKECLKKQLEFCFSRENLSKDLYLMSQMDSDQFVPVWTIANMEGI 167

  Fly   104 KTLTQDVQQIAKALSNSQLLELDETELKVKRRTKLPDQRDVNDKTLYVEALPANATHDWLKEVFS 168
            |.||.|:..|...|.::.::::||...||:     |:.:..   .:.:..:|.....:.:|.:|.
 Frog   168 KKLTTDMDLILDVLRSTPVVQVDEKGEKVR-----PNHKRC---IIILREIPETTPVEEVKALFD 224

  Fly   169 RYGPVAYVSLPHYPGTKKIKEFA-----FIEFEKSGSLEKA-------VKAF------AQIQGV- 214
            .......:|.          |||     ::.|:.....::|       ||.|      |:|:.:
 Frog   225 NENCPKVISC----------EFAHNNNWYVTFQSDTDAQQAFRYLREEVKTFQDKPIMARIKAIN 279

  Fly   215 ------------LSVETDP----SDLAS------VRSFQQQQQI-----QQKAEQPQSEAEQVEL 252
                        .||.|.|    :..||      |.:..||..|     |..:..|....|....
 Frog   280 TFFAKNGYRTVDSSVYTQPVQTQAQFASPLFMQPVYNAHQQYSIYNIVPQTWSPNPAPYFETPLA 344

  Fly   253 PKRN------LKREATDKDREEIHEV------KRVKLEEGQPSETST-------AGETASE---- 294
            |.:|      .....|.|.......|      .|||    .|..|||       .|.||:.
 Frog   345 PFQNGGFVNGFNSSGTYKASSASMSVGRPFHRNRVK----PPFRTSTNTSERPDIGTTATSVSLD 405

  Fly   295 ------------TDAEGTAEASEQEDKTEATD---------GDEAAKKRRR-----KRKK----- 328
                        ::..||:..:.|:....:.|         |.|.|.:.||     :|::
 Frog   406 VSISRTNPRSYTSEKHGTSLGTHQDHSFSSKDTLPLHIEQNGTEGAVRGRRNTFRGRRRRDDDRS 470

  Fly   329 -------KAIVDKPNIEPSALELKVLPKTSWSSMRNKYLNLQRRIVSEAKSKLWRENH------- 379
                   :.:...|..:..|.....||.:..||.....  |:.|:....|.....:.|
 Frog   471 SRPLTSMEEVEQTPKFDLLASNFPPLPGSLVSSPGEPV--LESRMADVVKGICKEKEHKDPPVNL 533

  Fly   380 ------------PQNQQHPHHQQTSHPNHPKPSQLPE--AVKEEETGGEVPSDGGEGAVEAAPV- 429
                        ||...|..|..|:....|.|...|.  .:.|::.......|.......|||:
 Frog   534 STNTQEEPTKILPQPITHTIHPSTAELTPPPPPTPPSNTVLYEKKIEISCHKDVASQTSVAAPLC 598

  Fly   430 ---PAKRRKAVHKMNMNFYGAGGVESTK------SEEPSQERTPLFKYEPGLIVECSLLKPCTNV 485
               |.|:.||....::: ......|..|      .::|.:|:.| ...:|...:..:...|..|.
 Frog   599 TSSPGKQPKATSTASVS-TALNTQEPRKLSYAEVCQKPPKEQAP-SPVQPLRELRTNTTSPGKNE 661

  Fly   486 KEF---KAEMRQYPDIKYVDIKEGDQVALLRLGTPAAAEELLRQVNCSERQLKVLSGQQETLYWR 547
            :..   |||.......:.:| |..|.......|||.|....||
 Frog   662 ENCIPEKAEKSLEKSHEKLD-KVKDSPGHRSNGTPRAGTGKLR---------------------- 703

  Fly   548 KIEQDRE-AKLSKKVRVQQKRGREK 571
              ||.|: .:.|....|.::.|:|:
 Frog   704 --EQRRQFGRRSSPQGVMRRNGKEQ 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Larp7	NP_524795.2	LA	57..135	CDD:128955	25/77 (32%)
		RRM1_LARP7	148..220	CDD:409732	16/102 (16%)
		RRM2_LARP7	471..548	CDD:409958	14/79 (18%)
larp4	NP_001135708.1	LARP_4	124..198	CDD:153404	24/78 (31%)
		RRM_LARP4	203..279	CDD:410106	14/88 (16%)