DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ph-d and SCML1

DIOPT Version :9

Sequence 1:	NP_524794.2	Gene:	ph-d / 44889	FlyBaseID:	FBgn0004860	Length:	1537	Species:	Drosophila melanogaster
Sequence 2:	XP_005274635.1	Gene:	SCML1 / 6322	HGNCID:	10580	Length:	330	Species:	Homo sapiens

Alignment Length:	168	Identity:	56/168 - (33%)
Similarity:	76/168 - (45%)	Gaps:	27/168 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1383 ESYQTVS-DALPIQAATPEVPPI---------SMPVLAAMSTSSPLSLPLTLPLPIA--IAPTVS 1435
            |.||... :..||.:.||.  |:         ..|..|:...:...|..|.|..|.|  |..|.|
Human   163 EEYQRAELEEDPILSRTPS--PVHPSDFSEHNCQPYYASDGATYGSSSGLCLGNPRADSIHNTYS 225

  Fly  1436 LPVVSAGVVAP--VLAIPSSN----INGSDRPPISSWSVEEVSNFIRE---LPGCQDYVDDFIQQ 1491
            ....||   ||  |...|..|    ..||.....|:||||.|..|:::   |..| ..||.|...
Human   226 TDHASA---APPSVTRSPVENDGYIEEGSITKHPSTWSVEAVVLFLKQTDPLALC-PLVDLFRSH 286

  Fly  1492 EIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKE 1529
            ||||:|||||..:.|:..:|:|||.|:|:...::.:|:
Human   287 EIDGKALLLLTSDVLLKHLGVKLGTAVKLCYYIDRLKQ 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ph-d	NP_524794.2	SAM_Ph1,2,3	1461..1529	CDD:188976	28/70 (40%)
ph-d	NP_524794.2	SAM	1464..1529	CDD:197735	28/67 (42%)
SCML1	XP_005274635.1	SAM_Scm	253..324	CDD:188977	28/71 (39%)
SCML1	XP_005274635.1	SAM	256..324	CDD:197735	28/68 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8350
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950