Protein Alignment ph-d and phc3

DIOPT Version :10

• Sequence 1: NP_524794.2
• Gene: ph-d / 44889
• FlyBaseID: FBgn0004860
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_001430217.1
• Gene: phc3 / 558094
• ZFINID: ZDB-GENE-070912-369
• Length: 890
• Species: Danio rerio
• Alignment Length: 1028
• Identity: 235/1028 - (22%)
• Similarity: 355/1028 - (34%)
• Gaps: 347/1028 - (33%)

  Fly   689 STTGTPITLQNGQTLHAATAAGVDKQQQQL--QLFQKQHILQQQMLQQQIAAIQMQ--QQQAAVQ 749
            |||.|. |...|.::.:...:. |:|..|:  |...:...:..|.|||..||.|..  .|.||:|
Zfish    22 STTATS-TTPTGTSIPSGNISS-DRQAVQVIQQTLHRPQSMTAQYLQQMYAAQQQHILLQTAALQ 84

  Fly   750 AQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQV 814
            .|||.||.::..|.:......|....:|..:..........|            |||.||..:.:
Zfish    85 QQQQHQQNLTATQILTTTDMAAQTNGRQFTSSPSSSNGNAPQ------------LANVTQTSIPI 137

  Fly   815 APNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQST 879
             |...:|                   |..|:.||.:......           :|.||.::..::
Zfish   138 -PTSPVT-------------------QPMARIQVTSSSSTGG-----------DISQQAMLLGNS 171

  Fly   880 GATSQQQQQQPQQQSGQLQLSSVPFSVSPSMTAEDIAGITS-SALQEALSVS------GAI---- 933
            ..|..|.|...:.|...|..::...:|.|.:|.  ::.|:| ||..:..|::      ||:
Zfish   172 SPTGSQAQMYLRTQMLILTPAATVAAVQPDLTV--VSSISSQSASSQVQSLALRTHLPGALTTSQ 234

  Fly   934 -FQTTKPI-------------TC--SSSTLPTSSVVTITS----------QSSTPLVTSSTVASM 972
             .|...|:             .|  .|:.||.:.|.|..|          .|:.|.:..||...:
Zfish   235 NIQIKPPLQGQTLVSPPPKMSICPLKSTQLPQNLVETSRSVSVLNNVTQTPSAQPAIPPSTFTPV 299

  Fly   973 QQAQTQGTQIH-------------------QHQQL----ISATIAGGSQ---------------- 998
            |..|....|:|                   .|:||    :..|...||.
Zfish   300 QSHQLIRHQLHCPSGPRVAPQHLIIQQSSSTHRQLHPITLRVTAQDGSPTPFTLQTRTTPTTATV 364

  Fly   999 QQQQQQQLGLPSLTPTTPSPT--TNPILAMTSMMNATVG----------HLSTAPPVSV------ 1045
            |.||.:.|.:||.|..|.:.|  |:|...:.......:|          .||..||:.:
Zfish   365 QSQQTELLSVPSSTNQTANQTKYTSPPAVLPDPPPLHLGPALEPVSQYTPLSCPPPLKLVQPQRL 429

  Fly  1046 ---SSTAVTPSSGQLVTLSSASSGGGAGFPAT------PTKETPSKGPTATLVPID---SPKTPV 1098
               |..||...|..  ||.|...     .|.|      |.:..|   |..| |.:|   .|.|..
Zfish   430 ALRSVQAVEVQSDH--TLLSEEE-----LPLTEAVLQLPFQSLP---PPQT-VAVDLKVQPATQT 483

  Fly  1099 SGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSST 1163
            .........:|.....|:.:..||.......|:.....||..|.:.:...|.:..|.........
Zfish   484 EASQVTPLLESVNLTLVTDAEHASPPQNSRTSSSPTLSRSDEPQRSSDVVTDQPENLTADQEQPC 548

  Fly  1164 IPNS---VSGKEEPKLTTCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTS 1225
            :|:|   :...|||        |.|||                             :.|...:::
Zfish   549 VPSSRSVIRSPEEP--------THATS-----------------------------SPSPLLSSA 576

  Fly  1226 CTSTTTTTTSSISNGSKDLP-KAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYA----------- 1278
            ..|::..:::|:....:..| :|:.:|::|||:|:||:|:|..|||||   |:|
Zfish   577 VRSSSRLSSASLPESPEGRPSQAISRPHILTHLIEGFVIREGLEPFPV---RHASLEMNLQATLP 638

  Fly  1279 --------------------DKDVSDEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKME-HK 1322
                                |.|:.|...:.:.|::   ||        .:::.||.|||.. .:
Zfish   639 ENREDGESALIDADHPDSSSDSDIDDPLAEDEQTVE---KL--------PEVLECEFCGKRGLAQ 692

  Fly  1323 AKLKRKRYCSPGCSRQ----------------------AKNGIGGVGSGETNGLGTGGIVGVDAM 1365
            |.|:.||:||..|:|:                      ...|..|..|...||
Zfish   693 AFLRSKRFCSMTCARRFNLRCKKRLNRLREEKVTYWPHRSMGKRGRPSRCLNG------------ 745

  Fly  1366 ALVDRLDEAMAEEKMQTESYQTVSDALPIQAATPEVPPISMPVLAAM------------------ 1412
            :..:.|.....:...|....|.||:::.::....|.||..|.....:
Zfish   746 SAREHLPRPQLQGSHQASDNQMVSNSVWMEREEEEDPPGPMTTRLRLQAEREKEQNREQEQSRVE 810

  Fly  1413 -STSSPLSLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNINGSDRPPISSWSVEEVSNFIR 1476
             |:||.|.|                                      |..| |.||||:|.:||.
Zfish   811 SSSSSELLL--------------------------------------DSSP-SQWSVEQVCSFIS 836

  Fly  1477 ELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKE 1529
            .||||.|...:|..|||||||||||.|:||::||.:||||||||.|.:.::|:
Zfish   837 TLPGCHDVAAEFGCQEIDGQALLLLTEDHLMSAMNLKLGPALKICAHINTLKQ 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-d	NP_524794.2	SAM_Ph1,2,3	1461..1529	CDD:188976	40/67 (60%)
phc3	NP_001430217.1	None