Protein Alignment ph-d and phc1

DIOPT Version :10

• Sequence 1: NP_524794.2
• Gene: ph-d / 44889
• FlyBaseID: FBgn0004860
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_991270.2
• Gene: phc1 / 403008
• ZFINID: ZDB-GENE-081022-39
• Length: 897
• Species: Danio rerio
• Alignment Length: 1098
• Identity: 273/1098 - (24%)
• Similarity: 402/1098 - (36%)
• Gaps: 300/1098 - (27%)

  Fly   509 NQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQ 573
            ::|.....|.:.::.|.|.||..|.|                     |...|..||:     ..|
Zfish    23 SRPPQIAQMSLYERQAVQALQALQRQ---------------------PNAAQYFQQL-----MLQ 61

  Fly   574 QQLAVATAQLQQ--QQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKA--KMRNK 634
            ||:..||.||..  ..||.|.||.::..:|    |.:..:|.|  |.|...|.|...|  .|.|
Zfish    62 QQINSATCQLHNLAAVQQATLAASRQSSSP----NNSASQPTS--SAQCTVNLSTTSAGGTMTN- 119

  Fly   635 QQPVRPALATLKTEIGQ--VAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITL 697
            .:|:.||.:...|.:.|  :.|.|       :..|.|....:.:.:.|.....::....||
Zfish   120 PRPIGPATSAASTALSQSVLLGGN-------SGGQGQMYLRVNRSLRAPLTPQLIFMPGGT---- 173

  Fly   698 QNGQTLHAATAAGVDKQQQQLQLFQKQHILQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQ 762
               .|...||.|....|||.                      |.||||.|.......|   |...
Zfish   174 ---ATATVATVAQTQPQQQP----------------------QQQQQQEATPTSSSSQ---SDND 210

  Fly   763 QVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQ 827
            ||.....:.|:..:.|..:.:...|::.........|.|             .|.||..|.||
Zfish   211 QVQNLAMRCVSTPRAATVKTEFADRKETTGTFPLNQQTQ-------------TPQQFGQSTQQ-- 260

  Fly   828 QQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSTGATSQQQQQQPQQ 892
                    :|.|.|..|.|::|:..............:..|  |..|..|..||:|......|
Zfish   261 --------VQPQTQPLANAKLQSFSNTANPSVPALNVKPNN--QSAVAPQQAGASSNPPSSSP-- 313

  Fly   893 QSGQLQLSSVPFSVSPSMTAEDIAGITSSALQEALSVSGAIFQTTKPITCSSST-----LPTSSV 952
                  ..|:|.|                  |..||.||  ...|:.:..|::|     :|||:|
Zfish   314 ------TPSLPLS------------------QLLLSQSG--LHQTRGVPASTATVTHILVPTSNV 352

  Fly   953 VTITSQSSTPLVTSSTVASMQQAQTQGTQIHQH--QQLISATIAGG----------SQQQQQQQQ 1005
            .  ||....||.|.:|.::| .|||...|..|.  ..|.:..:|.|          :|..:...|
Zfish   353 P--TSTQGYPLGTVATKSNM-TAQTLVVQPLQQTGANLSTEKLAHGTGHVPIQPKTAQGHRVPVQ 414

  Fly  1006 LGLPSLTPTTPSPTTN------------PILAMTSMMNATVGHLSTAPPVSVSSTAVTP------ 1052
            :......|..|:|..|            |: .:.....:|:|: |.|..::.:.|..:.
Zfish   415 MSPRHPPPILPAPPNNGQATAGLHPPHVPV-QLVGARQSTLGN-SQALALAQARTCCSQQDGTAA 477

  Fly  1053 ----SSGQLVTLSSASSGGGAGFPATPTKETPSKGPTATLVPIDSPKTPVSGKDTCTTPKSSTPA 1113
                :.|.:||:.:|....|||......:         :.:||...:|..|...|     ...||
Zfish   478 VGVNNPGNVVTMVTAMDTSGAGMCLKTAQ---------SALPISQMQTNQSAVLT-----QGNPA 528

  Fly  1114 TVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKL-T 1177
            :|:.|::..:::|::|....|    ....|.|..|..::|.:.:....|..|  :||  .|.: .
Zfish   529 SVTHSMDGQNNSGDSLFVQSA----QAQIKPAIGPIKRKSESDLTHEISNEP--ISG--SPSMQD 585

  Fly  1178 TCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSK 1242
            :...|:.|.|..|...|             |.|:..|.:          .|...........|.:
Zfish   586 SAPPLSPAPSLDTVPEI-------------AFSSPPTLS----------LSLPVPLPRGAGQGDR 627

  Fly  1243 -DLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAP 1306
             .:|:|::||.||||:|:||:|||..||||||...   |::|...|  .....|||:
Zfish   628 APVPQAVVKPQVLTHLIEGFVIQEGAEPFPVTGPL---KELSGAVP--PILHPEDIR-------- 679

  Fly  1307 GSDMVACEQCGKMEHKAKLKR-KRYCSPGCSR----------QAKNGIGGVGSGETNGLGTGGIV 1360
             ||.:.||.|......::.:| ||:|:..||:          :|..|:.|...      ..||.|
Zfish   680 -SDKLKCEYCLNFAPASQFRRSKRFCTISCSKRYNVSFRNHLRASRGLEGAER------PAGGPV 737

  Fly  1361 GVDAMALVDRLDEAMAEE-------------KMQTESYQTVSDALPIQAATPEVPPISMPVLAAM 1412
            ..|.:|. .|.....:.|             |.::||.:  ||.:.......|...:|      :
Zfish   738 VQDVIAR-RRAPRRSSSEIACAKITGRHLPVKCRSESSR--SDDISSCEGEEEEDFLS------L 793

  Fly  1413 STSSPLSLPLTLPLPIAIAPTV------SLPVVSAGVVAPVLAIPSSNINGSDRPPISSWSVEEV 1471
            |.||..|    .|.|....|.:      .|||             ..|...|..|  :.|||:||
Zfish   794 SPSSTFS----CPRPTHCGPQLDDTAPGGLPV-------------DENHFLSGNP--ADWSVQEV 839

  Fly  1472 SNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIVAKVESIKE 1529
            ..||..|.||:|....|:.||||||||:||||.||::.|.:||||||||.|.:.|:::
Zfish   840 CQFISSLQGCEDLASQFLSQEIDGQALMLLKEEHLMSTMNIKLGPALKICASINSLRD 897

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-d	NP_524794.2	SAM_Ph1,2,3	1461..1529	CDD:188976	38/67 (57%)
phc1	NP_991270.2	None