DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ph-d and L3mbtl3

DIOPT Version :9

Sequence 1:	NP_524794.2	Gene:	ph-d / 44889	FlyBaseID:	FBgn0004860	Length:	1537	Species:	Drosophila melanogaster
Sequence 2:	XP_003748714.1	Gene:	L3mbtl3 / 309550	RGDID:	1305474	Length:	868	Species:	Rattus norvegicus

Alignment Length:	333	Identity:	78/333 - (23%)
Similarity:	123/333 - (36%)	Gaps:	98/333 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly  1216 TTSSGTFTTSCTSTTTTTTSS-------ISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVT 1273
            |.||.:|..|..:.|..::||       .:|..:|..|.  |.|.:....:..:::|  ||.|..
  Rat   604 TPSSFSFPRSKRTDTNESSSSPETRDQHANNVKEDSEKK--KENEVKTSAEAKVVRE--EPTPSV 664

  Fly  1274 RQRYADKDVSDEPPKK--KATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKRKRYCSPGCS 1336
            :|        .:||::  ||.....|:       |........|....:.:|:..::...:|
  Rat   665 QQ--------TQPPQQALKAPQAPQIQ-------PAQQAPQAPQAQPTQQQAQQAQQAPQAP--- 711

  Fly  1337 RQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTE-SYQTVSDALPIQAATPE 1400
             ||:                                  .|.:..||. :.|....|.|.|....:
  Rat   712 -QAQ----------------------------------PAPQAPQTHPTQQQAQQAQPTQQQAQQ 741

  Fly  1401 VPPISMP---------VLAAMSTSSPL-SLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNI 1455
            ..|....         ....:|...|: .|||.......:.|||:             .||:|.
  Rat   742 AQPTQQQQAQQQAQRRSAVFLSFKPPIPCLPLRWEQQSKLLPTVA-------------GIPASR- 792

  Fly  1456 NGSDRPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKI 1520
                   :|.||.:|||.||:.||||:::...|..::|||:|.||:.:..:|..|.:||||||||
  Rat   793 -------VSKWSTDEVSEFIQSLPGCEEHGKVFKDEQIDGEAFLLMTQTDIVKIMSIKLGPALKI 850

  Fly  1521 VAKVESIK 1528
            ...:...|
  Rat   851 FNSILMFK 858

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ph-d	NP_524794.2	SAM_Ph1,2,3	1461..1529	CDD:188976	30/68 (44%)
ph-d	NP_524794.2	SAM	1464..1529	CDD:197735	30/65 (46%)
L3mbtl3	XP_003748714.1	MBT	235..331	CDD:214723
		MBT	342..438	CDD:214723
		MBT	450..542	CDD:214723
		SAM_Scm-like-3MBT3,4	793..858	CDD:188981	29/64 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910