Protein Alignment ph-d and phc3

DIOPT Version :9

• Sequence 1: NP_524794.2
• Gene: ph-d / 44889
• FlyBaseID: FBgn0004860
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: XP_004914480.1
• Gene: phc3 / 100496983
• XenbaseID: XB-GENE-6258800
• Length: 973
• Species: Xenopus tropicalis
• Alignment Length: 1242
• Identity: 291/1242 - (23%)
• Similarity: 433/1242 - (34%)
• Gaps: 403/1242 - (32%)

  Fly   413 VTTTSSTVQAATGPGST-------GSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQS 470
            :||:|:|....|...:.       ||:....||.:||...:.|.:..|.:|...|         :
 Frog     7 ITTSSATATTTTSSSANPPPISVYGSSDRHAVQVIQQALNRPTSSAAQYLQQMYS---------A 62

  Fly   471 VQTAQLLNAGQAQQMQIPWFWQNAAGLQPFGSNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQI 535
            .|...:|......|..:     |::.||...|.|          |.....::|:..::.|.|
 Frog    63 QQQHLMLQTAALHQQHL-----NSSPLQTISSVQ----------QSNVTGERPSISSVSTTQ--- 109

  Fly   536 IQCNVTQTPTKARTQLDALAPKQQ--QQQQQVGTTNQTQQQQ----------LAVATAQLQQQQQ 588
             |.|..||    ..||....|..|  .:.|...||:.:..|:          |:.:.||:..:.|
 Frog   110 -QSNAPQT----SIQLSTSPPPPQLLSRSQTSSTTSSSITQKTVLLGSTSPTLSASQAQMYLRAQ 169

  Fly   589 QL------TAAALQRPGAPVMPHNGTQVRPASSVSTQ--TAQNQSLLKAKMRNKQQPVRPALATL 645
            .|      |.||:| ...||:..:.:......| :||  |.::|.:|:....|...| :|:
 Frog   170 MLIFTPAATVAAVQ-SDIPVISSSSSSSSSCQS-ATQNLTIRSQPMLEMSFPNNSPP-KPS---- 227

  Fly   646 KTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAG 710
                  ...|...:.|.|||               |.:|     |..|..|::|.|
 Frog   228 ------NQDQPLAICHKTTV---------------ASSK-----TIHTDATMENNQ--------- 257

  Fly   711 VDKQQQQLQLFQKQHILQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQ 775
              |....:...:...:.:...:.|.||.:..
 Frog   258 --KNDSSMSDSRCTAVTRTSNIHQLIAPVSY---------------------------------- 286

  Fly   776 QQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQL 840
                                 ...|..:|..  ...:.:.|:              |.:|.||.:
 Frog   287 ---------------------STVHSHSLGK--HPAISILPD--------------HPKLPQQVI 314

  Fly   841 QQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSTGATSQQQQQQPQQQSGQLQLSSVPFS 905
            .||             |||.|.|.|    ||.|.:..|.......|...|.|....:.:.|...|
 Frog   315 LQQ-------------QQQIQHRHQ----IQTITLHNSALEPPSTQHCVPMQSQSFVHIPSSAHS 362

  Fly   906 --VSPSMTAEDIAGITSSALQEALSVS-----------------GAIFQTTKPITCSSSTLPTSS 951
              .:|..||.......|...|.::.||                 .||.|....:.. .|||||..
 Frog   363 HHCTPVTTALSPPPTISQPAQPSVVVSPPPPHSPCQSPTIIIHPQAIIQPQTSLLV-QSTLPTRD 426

  Fly   952 VV---TITSQSSTPLVTSSTVASMQQAQTQGTQIHQHQQLISAT---IAGGSQQQQQQQQLGLPS 1010
            .:   ..|:..|.|.::.||    ....|..:..||...|:|::   |:..||.||.:.| .:|
 Frog   427 NLHHPLQTTLHSAPQMSLST----HLPPTLSSGPHQQHALVSSSPQIISPISQTQQPEIQ-SIP- 485

  Fly  1011 LTPTTPS----PTTNP----ILAMTSMMNATV-GHLSTAPPVSVSSTAVT----PSSGQLVTLSS 1062
             |||..|    |||.|    .|.:.||....| ..:.|...|.:.:..:|    |::..||.|.
 Frog   486 -TPTVASSPHLPTTPPSQLQALPLQSMQTIPVQPEILTPGQVLMQNALLTEEELPAAEALVQLP- 548

  Fly  1063 ASSGGGAGFPATPTKETPSKG----PTATLVPI------DSPKTPVSGKDTC--TTPKSSTPATV 1115
                    |...|..:|.:..    |.|...|:      ..|:..|..:| |  ...::.||.|:
 Frog   549 --------FQTLPPPQTVAVNLHIQPAAVESPVVYQVENVCPEEAVVQED-CVGVITQTRTPPTM 604

  Fly  1116 SASVEASSSTGEALSNGDASDR---SSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKLT 1177
            ..| :...|:||.|. .|.:.|   |.|.|.||         :.::.||.|...|:..   |.|.
 Frog   605 LPS-DLPESSGEGLP-PDPTLRVLPSITSSVGA---------SVIKSPSDTSHMSIPA---PPLL 655

  Fly  1178 TCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSK 1242
                |.:||:.|..|...|.|                                        .|..
 Frog   656 ----LPAATTRSNRTLKPNSI----------------------------------------PGLD 676

  Fly  1243 DLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQ----RYADKDVS--DEPPKKKATMQEDIKLSG 1301
            .||.|::||.:|||||:||:|||..|||||.|.    ..|.|.:|  ||.....|.|:.||:.|
 Frog   677 KLPHAIVKPQILTHVIEGFVIQEGVEPFPVNRSSLLVEQAVKPLSPLDEGNLNIADMKSDIQSS- 740

  Fly  1302 IASAPGS---------------------DMVACEQCGKMEHKAKLKR-KRYCSPGCSRQAKNGIG 1344
             |..|.:                     :::|||.|||..:..|.:: :|:||..|:::
 Frog   741 -AKLPDNSTDTDMEDLTAEADCMDELECELLACEFCGKTGYPNKFRQSERFCSLSCAKR------ 798

  Fly  1345 GVGSGETNGLGTGGIVGVDAMALVDR-LDEAMAEEKMQTESYQTVSDALPIQAATPEVPPISMPV 1408
             ..:..|..|   |:...:..:...| :|.::.:....:.|..:|.:....|    ::|......
 Frog   799 -YNANSTKQL---GLFKANKTSRWSRKVDGSIGQRGRPSSSAGSVREHYLRQ----QLPTAYSYT 855

  Fly  1409 LAAMSTSSPLSLPLTLPLPIAIAPTVSLPVVSAGVVAPVLAIPSSNINGSDR-------PPI--- 1463
            ..|:..|...|..:|:...:.                     ..|.....:|       ||.
 Frog   856 SEALENSQEDSTRVTMTTRLR---------------------RQSEREREERQRRQMRKPPCQRS 899

  Fly  1464 -------SSWSVEEVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKENHLVNAMGMKLGPALKIV 1521
                   |.|:||:|..||..||||.|..|:|..|||||||||||||:||:..|.:||||||||.
 Frog   900 PDTQTEPSLWTVEDVWAFIHALPGCHDIADEFRTQEIDGQALLLLKEDHLMGTMNIKLGPALKIC 964

  Fly  1522 AKVESIK 1528
            |.:.|:|
 Frog   965 AWINSLK 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-d	NP_524794.2	SAM_Ph1,2,3	1461..1529	CDD:188976	43/78 (55%)
		SAM	1464..1529	CDD:197735	41/65 (63%)
phc3	XP_004914480.1	Atrophin-1	341..>648	CDD:367360	84/335 (25%)
		SAM_Ph1,2,3	904..971	CDD:188976	40/66 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7713
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I3932
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9439
Panther	1	1.100	-	-	O	PTHR12247
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060