Protein Alignment ph-d and phc1

DIOPT Version :10

• Sequence 1: NP_524794.2
• Gene: ph-d / 44889
• FlyBaseID: FBgn0004860
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: XP_031761253.1
• Gene: phc1 / 100488113
• XenbaseID: XB-GENE-1013248
• Length: 852
• Species: Xenopus tropicalis
• Alignment Length: 944
• Identity: 245/944 - (25%)
• Similarity: 359/944 - (38%)
• Gaps: 211/944 - (22%)

  Fly   698 QNGQTLHAATAAGVDKQQQ--QLQLFQKQHI---------------LQQQMLQQQIAAIQMQQ-- 743
            ||..:.:.::|:|...:.|  |:.|:::|.:               ..|.|||||::..|:..
 Frog     7 QNSSSTNGSSASGSSTRPQISQMSLYERQAVQALQALHRQPNAAQYFHQLMLQQQLSNAQLHSLA 71

  Fly   744 --QQAAVQAQQQ---------QQQQVSQQQQVN----------AQQQQAVAQQQQAVAQAQQQQR 787
              |||.:.|.:|         ||...:|..|.|          ::.|...|.....:.|:.....
 Frog    72 AVQQATIAASRQAASPNTGSAQQTNTTQGSQANLSTSSSAQLLSRTQNVTAPSATTLTQSVLLSN 136

  Fly   788 EQQQQVAQAQAQ---HQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQ 849
            .....:.|:|.|   .|..|.|    :|||       :....:...|::|||   |.......||
 Frog   137 ASSPPLGQSQTQMYLRQPQLGN----LLQV-------NRSLGRGVPLNSQLI---LMPNGSVAVQ 187

  Fly   850 AQVQA-QAQQQQQQREQQQNII----QQIVVQQSTGATSQQ-------QQQQPQQQSGQLQLSS- 901
            .:|.: |.|...|..:|.||:.    |......:.|||..|       .|..|...:...|:.|
 Frog   188 QEVTSPQNQGVHQDSDQVQNLAVRGQQTAATTSAAGATISQPAPLATKPQIHPASSAAPTQIPSP 252

  Fly   902 -VPFSVSPSMTAEDIAGITSSALQ---EALSVSGAIFQTTKPITCSSSTLPTSSVVTITSQSSTP 962
             ||.||...:.:  ..|..|...|   |.....|...|.:..|..:.:..|..:...|:|.:.|.
 Frog   253 NVPQSVKNPVGS--TGGTVSQGSQTEAEGRKADGEGVQQSVGINLTRAATPAPNQTLISSATYTH 315

  Fly   963 LVTSSTVASMQQAQTQGTQIHQHQ--QLISATIAGGSQQQQQQQQLGLPSLTPTTPSPTTNPILA 1025
            :...|.:...|....|...||||:  ||:.|:......|.|...|.||       .:|.|...|.
 Frog   316 IQPHSVLQQKQVVFQQQIAIHQHRQSQLLHASTHLQLAQPQAATQQGL-------QTPGTQQTLV 373

  Fly  1026 MTSMMNAT-VGHLSTAPPVSVS----STAVTPSSGQLVTLSSASSGGGAGFPATPTKETP----- 1080
            :..|:.|| ...:.|..||.:.    ...|.|.:.| ..|.:.:|.|....| .|:...|
 Frog   374 VQPMLQATSESAIPTKAPVPIQPKQPGKGVPPLNLQ-GHLGAKASQGTRPLP-IPSPSQPHIPVQ 436

  Fly  1081 -----SKGPT------ATLVPIDSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDA 1134
                 .:||.      ||.||     :..|.....|.|.|  ||.|::.|..:....:|...|..
 Frog   437 LVGARQQGPAQALALGATQVP-----SQASSMTQLTLPPS--PAPVASVVAGAVQESQAGFYGVL 494

  Fly  1135 SDRSSTPSKGATTPTSKQSNAAVQPPSSTIPNSVSGKEEPKLTTCGSLTSATSTSTTTTITNGIG 1199
            ..:.|.|.|........:.:.:|.|..::.|.......|...|......:||..|.|.|:
 Frog   495 QGKLSGPGKRKAEVEDDRDDPSVLPVKASPPTDAPPTVEETSTPADKPEAATQVSPTLTV----- 554

  Fly  1200 VARTTASTAVSTASTTTTSSGTFTTSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQ 1264
                                    .:.||....:.||..:.....|:|::||.:|||:|:||:||
 Frog   555 ------------------------LAPTSVPALSISSRQHSDSKPPQAIVKPQILTHIIEGFVIQ 595

  Fly  1265 EANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAP-------------GSDMVACEQC 1316
            |..|||||     ....:..||.|:.|:  :.:.|....|.|             .|.::.||.|
 Frog   596 EGAEPFPV-----GSPQLLKEPEKQAAS--DTVLLPPAESPPPQAVGDTAASDSGSSKLLKCEYC 653

  Fly  1317 GKMEHKAKLK-RKRYCS--------PGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLD 1372
            ||.....:.: .||:||        ..||.|.:     :...:...|...|  ||.|.....|.:
 Frog   654 GKYAPAEQFRGSKRFCSMTCAKRYNVSCSHQFR-----LKRKKLKELQEAG--GVRARRRGPRRN 711

  Fly  1373 EA-MAEEKMQTESYQTVSDALPIQAATPEVPPISMPVLAAMSTSSPLSLPLTLPLPIAIAPTVSL 1436
            .: :|..|:|.:..:..|......::..|          |.|.:||            ..|:...
 Frog   712 SSEIARAKIQGKRMREDSSRGSDNSSYDE----------AFSPNSP------------APPSCRT 754

  Fly  1437 PVVSAGVVAPVLAIPSSNING------SDRPPISSWSVEEVSNFIRELPGCQDYVDDFIQQEIDG 1495
            |........|.....:|::.|      |..|  |.||||||..||..|.||||..:||..|||||
 Frog   755 PHGDRDGSTPTGGPSNSDLLGINPMFLSSNP--SRWSVEEVYEFISSLQGCQDLAEDFRSQEIDG 817

  Fly  1496 QALLLLKENHLVNAMGMKLGPALKIVAKVESIKE 1529
            ||||||||.||::|:.:||||||||.||:..:||
 Frog   818 QALLLLKEEHLMSALNIKLGPALKICAKINLLKE 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ph-d	NP_524794.2	SAM_Ph1,2,3	1461..1529	CDD:188976	43/67 (64%)
phc1	XP_031761253.1	PHA03247	<381..631	CDD:223021	70/294 (24%)
		PHC2_SAM_assoc	678..783	CDD:465202	23/133 (17%)
		SAM_Ph1,2,3	783..851	CDD:188976	43/69 (62%)