Protein Alignment mdy and ARE2

DIOPT Version :10

• Sequence 1: NP_609813.1
• Gene: mdy / 44887
• FlyBaseID: FBgn0004797
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_014416.1
• Gene: ARE2 / 855753
• SGDID: S000005302
• Length: 642
• Species: Saccharomyces cerevisiae
• Alignment Length: 596
• Identity: 121/596 - (20%)
• Similarity: 232/596 - (38%)
• Gaps: 165/596 - (27%)

  Fly    71 KVLDKDENGNGTN----GSEKKLRYRRTQS--------------------------------VTR 99
            :|::.|:|...|:    .|::|.|||:..|                                .|.
Yeast    88 EVIETDDNMFKTHVKTLSSKEKARYRQGSSNFISYFDDMSFEHRPSILDGSVNEPFKTKFVGPTL 152

  Fly   100 AEEISNKEEK---------QRRAQP------GR---------PIHRPRDSLFSWSSGF--TNFSG 138
            .:||..:|::         .|::.|      |:         |.....:::.:..:..  :||||
Yeast   153 EKEIRRREKELMAMRKNLHHRKSSPDAVDSVGKNDGAAPTTVPTAATSETVVTVETTIISSNFSG 217

  Fly   139 LVNWGFLLLCIGGLR-------------------------------------------LGLENLL 160
            |....::.:..|.::                                           :|::.|.
Yeast   218 LYVAFWMAIAFGAVKALIDYYYQHNGSFKDSEILKFMTTNLFTVASVDLLMYLSTYFVVGIQYLC 282

  Fly   161 KYGI-RINPLDWFFFISGHNEGEGHNALILSIYSLVHISLCL-AVEKGLAMEIIAEGLGLFIQIV 223
            |:|: :.....|.|               .|||..:.:...: ..|..|.:..:::   :|:.:.
Yeast   283 KWGVLKWGTTGWIF---------------TSIYEFLFVIFYMYLTENILKLHWLSK---IFLFLH 329

  Fly   224 NIVVLVCLPVVTIHLKGHAFSLMGASTVCFFYSVLFLKLWSYVQTNMWCRQTYYQKNPRERRPSI 288
            ::|:|         :|.|:|:         ||:..   ||...:...:.:....:.......|.:
Yeast   330 SLVLL---------MKMHSFA---------FYNGY---LWGIKEELQFSKSALAKYKDSINDPKV 373

  Fly   289 TLAELKKGV------LNGGEEDEDVSKLVQYPDNLTYKDLLYFLCAPTLCYELNFPRTSRVRKRF 347
             :..|:|..      |:.....:...|   :|:|::.|...:|...|||.|::.:|||..:|..:
Yeast   374 -IGALEKSCEFCSFELSSQSLSDQTQK---FPNNISAKSFFWFTMFPTLIYQIEYPRTKEIRWSY 434

  Fly   348 LLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPFSNMDVALATERLLKLA------LPNHL-CWL 405
            :|:::. .:.|...:|.:..|.::..|....:...|.:.....:||||..      :|..: .::
Yeast   435 VLEKIC-AIFGTIFLMMIDAQILMYPVAMRALAVRNSEWTGILDRLLKWVGLLVDIVPGFIVMYI 498

  Fly   406 CFFYLMFHSFLNAVGELLNFADRNFYCDWWNANNIDTFWRTWNMPVHRWCVRHLY-IPVVQMGYS 469
            ..|||::.:.||.|.||..|.||.||.||||..:...|.|.||:|||::.:||:| ..:.....:
Yeast   499 LDFYLIWDAILNCVAELTRFGDRYFYGDWWNCVSWADFSRIWNIPVHKFLLRHVYHSSMSSFKLN 563

  Fly   470 SRQASTIVFLFSAVFHEYLVSVPLQIYKIWAFMGMMGQIPLSAISKSIEKKLGPRMGNIIVWASI 534
            ..||:.:.|..|:|.||..:.|..:..:.:.|...|.|:||.|::.:...:....:||:|.|..|
Yeast   564 KSQATLMTFFLSSVVHELAMYVIFKKLRFYLFFFQMLQMPLVALTNTKFMRNRTIIGNVIFWLGI 628

  Fly   535 ILGQPLCIMAY 545
            .:|..:....|
Yeast   629 CMGPSVMCTLY 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mdy	NP_609813.1	MBOAT	115..545	CDD:445070	105/505 (21%)
ARE2	NP_014416.1	ARE1	106..642	CDD:227389	117/578 (20%)