Protein Alignment mdy and ARE1

DIOPT Version :10

• Sequence 1: NP_609813.1
• Gene: mdy / 44887
• FlyBaseID: FBgn0004797
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_009978.1
• Gene: ARE1 / 850415
• SGDID: S000000644
• Length: 610
• Species: Saccharomyces cerevisiae
• Alignment Length: 501
• Identity: 129/501 - (25%)
• Similarity: 223/501 - (44%)
• Gaps: 82/501 - (16%)

  Fly    87 KKLRYRRTQSVTRAEEISNKEEKQRRAQ--PGRPIHRPRDSLFSWSSGFTNFSGLVNWGFLLLCI 149
            |.|:..:|::....:......||..:|.  ||..:.             :||||:..:.::.|..
Yeast   148 KNLQLTKTKTKATVKTTVKTTEKTDKADAPPGEKLE-------------SNFSGIYVFAWMFLGW 199

  Fly   150 GGLRLGLENLLKYGIRINPLDWFFFISGHNEGEGHNALILSIYSLVHISLCL------------A 202
            ..:|...:....||...|.|:...:::            ..::::..:.|.:            .
Yeast   200 IAIRCCTDYYASYGSAWNKLEIVQYMT------------TDLFTIAMLDLAMFLCTFFVVFVHWL 252

  Fly   203 VEKGLAMEIIAEGLGLFIQIVNIVVLVCLPVVTIHLKGHAFSLMGASTV-CFFYSVLF-LKLWSY 265
            |:|    .||......|: .|:|..|..:| ||..:..:.|.....:.: .|.:||:| :|..|:
Yeast   253 VKK----RIINWKWTGFV-AVSIFELAFIP-VTFPIYVYYFDFNWVTRIFLFLHSVVFVMKSHSF 311

  Fly   266 VQTN--MW-CRQ--TYYQKNPRERRPSI---TLAELKKGV------LNGGEEDEDVSKLVQYPDN 316
            ...|  :| .:|  .|..|..::.:.|:   |...|:|..      ||...:|.|      :|:|
Yeast   312 AFYNGYLWDIKQELEYSSKQLQKYKESLSPETREILQKSCDFCLFELNYQTKDND------FPNN 370

  Fly   317 LTYKDLLYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPF 381
            ::..:...|...|.|.|::|:|||||:|.|::|:::. .:||...:|.:..|:.:..|....|.|
Yeast   371 ISCSNFFMFCLFPVLVYQINYPRTSRIRWRYVLEKVC-AIIGTIFLMMVTAQFFMHPVAMRCIQF 434

  Fly   382 SNMDV----ALATE---RLLKLALPNH-LCWLCFFYLMFHSFLNAVGELLNFADRNFYCDWWNAN 438
            .|...    ..||:   .||...:|.. :.::..||:::.:.||.|.||..||||.||.||||..
Yeast   435 HNTPTFGGWIPATQEWFHLLFDMIPGFTVLYMLTFYMIWDALLNCVAELTRFADRYFYGDWWNCV 499

  Fly   439 NIDTFWRTWNMPVHRWCVRHLYIPVVQMG---YSSRQASTIVFLFSAVFHEYLVSVPLQIYKIWA 500
            :.:.|.|.||:|||::.:||:|..  .||   .|..||:...|..||||||..:....:..:.:.
Yeast   500 SFEEFSRIWNVPVHKFLLRHVYHS--SMGALHLSKSQATLFTFFLSAVFHEMAMFAIFRRVRGYL 562

  Fly   501 FMGMMGQIPLSAISKSIEKKLGPRMGNIIVWASIILGQPLCIMAYY 546
            ||..:.|...:|:|.:...:..|::.|::....:..| |..||..|
Yeast   563 FMFQLSQFVWTALSNTKFLRARPQLSNVVFSFGVCSG-PSIIMTLY 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mdy	NP_609813.1	MBOAT	115..545	CDD:445070	122/468 (26%)
ARE1	NP_009978.1	ARE1	96..610	CDD:227389	129/501 (26%)