Protein Alignment mdy and SOAT1

DIOPT Version :9

• Sequence 1: NP_609813.1
• Gene: mdy / 44887
• FlyBaseID: FBgn0004797
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_003092.4
• Gene: SOAT1 / 6646
• HGNCID: 11177
• Length: 550
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 154/599 - (25%)
• Similarity: 229/599 - (38%)
• Gaps: 135/599 - (22%)

  Fly     5 KDPQDKEPGKAEQPTKNSGSSGVG--IMKRLRRSASATEHNLSSLRNRKSTQNLFDQHGNPIDLR 67
            :|...:.|.|....|.::|...:.  |.|:::.:|.|.|  |.....::...:..|...|.|:
Human    22 EDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEE--LKPFFMKEVGSHFDDFVTNLIE-- 82

  Fly    68 QYRKVLDKDENGNGTNGSEKKLRYRRTQSVTRAEEISNKEEKQRRAQPGR-PIHRPRDSLFSWSS 131
               |....|..|....          |.||...|: :|...|..||.|.: .|...|.||.....
Human    83 ---KSASLDNGGCALT----------TFSVLEGEK-NNHRAKDLRAPPEQGKIFIARRSLLDELL 133

  Fly   132 GFTNFSGLVNWGFLLLCIGGL-----------RLGLE-NLLKYGIRINPLD----WFFFIS---- 176
            ...:...:.:....||.:..|           ||.|| :||.|.....|..    |..|:|
Human   134 EVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSV 198

  Fly   177 ----------GHNEGEGHNALILSIYSLVHISLCLAVEKGLAMEIIAEGLGLFIQIVNIVVLVCL 231
                      |:::..  :.||.|::.                       |....|..|.||...
Human   199 PYFLFQHWATGYSKSS--HPLIRSLFH-----------------------GFLFMIFQIGVLGFG 238

  Fly   232 PVVTIHLKGHAFSLMGAST-VCFFYSVLF-LKLWSYVQTNMWCRQTYYQKNPRERRPSITLAELK 294
            |...:    .|::|..||. :..|..:.| :|..|:|:.|:          ||
Human   239 PTYVV----LAYTLPPASRFIIIFEQIRFVMKAHSFVRENV----------PR------------ 277

  Fly   295 KGVLNGGEEDEDVSKLVQYPDNLTYKDLLYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGV 359
              |||..:|.   |..|..|   |....||||.||||.|..::||...||..::..:..:|....
Human   278 --VLNSAKEK---SSTVPIP---TVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCF 334

  Fly   360 NVVMALFQQWIIPSVRN-SLIPFSNMDVALATERLLKLALPNHLCWLCFFYLMFHSFLNAVGELL 423
            ..|..:|::...|..|| ...|||...:.|.   :....||..|.....|:...|.:|||..|:|
Human   335 FYVYYIFERLCAPLFRNIKQEPFSARVLVLC---VFNSILPGVLILFLTFFAFLHCWLNAFAEML 396

  Fly   424 NFADRNFYCDWWNANNIDTFWRTWNMPVHRWCVRHLYIPVVQMGYSSR---QASTIVFLFSAVFH 485
            .|.||.||.||||:.:...::||||:.||.|...:.|...:.. :|.|   .|...||..|||.|
Human   397 RFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWF-FSKRFKSAAMLAVFAVSAVVH 460

  Fly   486 EYLVSVPLQ-----IYKIWAFMGMMGQIPLSAISKSIEKKLGPRMGNIIVWASIILGQPLCIMAY 545
            ||.::|.|.     ::.::.|.||    ..:.|.....||   .:.|:::|.|:.||..:.:..|
Human   461 EYALAVCLSFFYPVLFVLFMFFGM----AFNFIVNDSRKK---PIWNVLMWTSLFLGNGVLLCFY 518

  Fly   546 YHD-YVVQH--FKN 556
            ..: |..||  .||
Human   519 SQEWYARQHCPLKN 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mdy	NP_609813.1	MBOAT	115..545	CDD:294479	123/471 (26%)
SOAT1	NP_003092.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		4/16 (25%)
		MBOAT	171..520	CDD:281107	112/418 (27%)
		FYXDWWN motif. /evidence=ECO:0000303|PubMed:32433614	403..409		4/5 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275897at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920