DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mdy and are1

DIOPT Version :9

Sequence 1:	NP_609813.1	Gene:	mdy / 44887	FlyBaseID:	FBgn0004797	Length:	565	Species:	Drosophila melanogaster
Sequence 2:	NP_593707.1	Gene:	are1 / 2542851	PomBaseID:	SPAC13G7.05	Length:	537	Species:	Schizosaccharomyces pombe

Alignment Length:	498	Identity:	112/498 - (22%)
Similarity:	192/498 - (38%)	Gaps:	140/498 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 QRRAQPGRPIHRPRDSLFSWSSGFTNFSGLVNWGFLLLCIGGLRLGLE-----NLLKY---GIRI 166
            ||....|.|:.|         ..|..|..|.:..||::|:.....||:     |::::   |..|
pombe   123 QRDTLLGLPLAR---------QVFRQFFVLFSSDFLMICLSFFSYGLQVCIEKNMIRWANLGYTI 178

  Fly   167 NPLDWFFFISGHNEGEGHNALILSIYSLVHISLCLAVEKGLAMEIIAEGLGLFIQIVNIVVLVCL 231
            ..| |..|.           ::|::|.:.|..                                .
pombe   179 QTL-WQGFY-----------MVLAVYWVKHRD--------------------------------F 199

  Fly   232 PVVTIHLKGHAFSLMGASTVCFFY----SVLFLKLWSYVQTNMWCRQTYYQKNPRERRPSITLAE 292
            |:|.                |.|:    :||.:|.:||.....:..:.....|..|:     |.:
pombe   200 PIVQ----------------CVFFTLHCAVLIMKQFSYSHHMGYISEIRILHNEYEK-----LLK 243

  Fly   293 LKKGVLNGGEED--------------EDVSKL-----------------------VQYPDNLTYK 320
            ..:..||..|:|              |.:|.|                       |.||||:.:.
pombe   244 FVRECLNSTEKDEKYTFELTFPNKPAETISTLQAEEIVALTAKYLSRQMRSEVGNVVYPDNINFF 308

  Fly   321 DLLYFLCAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPFSNMD 385
            :.:.:|..|:|.|.:.|||.:..|..::..:.......:.:.:||...:.:||.    :...::|
pombe   309 NYVDYLLVPSLVYSMEFPRVAHFRWHYMAFKAGSTFGLLALTLALVDWYFVPSA----VAVKDLD 369

  Fly   386 ----VALATERLLKLALPNHLCWLCFFYLMFHSFLNAVGELLNFADRNFYCDWWNANNIDTFWRT 446
                :.:|...:.|:..|..:.:|..|||:|...|||..|:..||||.||..|||....|.|.|.
pombe   370 FIGKLRIAPLLMNKIMFPAIILYLIMFYLIFDCILNAFAEITKFADRGFYGAWWNTVTWDEFSRE 434

  Fly   447 WNMPVHRWCVRHLYIPVVQMGYSSRQASTIV--FLFSAVFHEYLVSVPLQIYKIWAFMGMMGQIP 509
            ||.|||.:.:||:|...:. |:..:::..::  ||.||:.||:::.:....::.:.....:.|||
pombe   435 WNKPVHVFLMRHVYHSSIS-GFKLKKSHAVLLTFLISALVHEFVMLLATGKFRCYILTFQLLQIP 498

  Fly   510 LSAISKSIEKKLGPRMGNIIVWASIILGQP-LCIMAYYHDYVV 551
            |..:.:....|....:||:..|..:..|.. |||:     |:|
pombe   499 LYDLQQMFAFKKRDILGNVFFWIGMFTGPSFLCIL-----YIV 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mdy	NP_609813.1	MBOAT	115..545	CDD:294479	108/485 (22%)
are1	NP_593707.1	ARE1	3..537	CDD:227389	112/498 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	134	1.000	Domainoid score	I1277
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I1408
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003134
OrthoInspector	1	1.000	-	-		mtm9286
orthoMCL	1	0.900	-	-		OOG6_101524
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2034
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.890