Protein Alignment mdy and are2

DIOPT Version :10

• Sequence 1: NP_609813.1
• Gene: mdy / 44887
• FlyBaseID: FBgn0004797
• Length: 565
• Species: Drosophila melanogaster
• Sequence 2: NP_588558.1
• Gene: are2 / 2538854
• PomBaseID: SPCP1E11.05C
• Length: 472
• Species: Schizosaccharomyces pombe
• Alignment Length: 489
• Identity: 129/489 - (26%)
• Similarity: 210/489 - (42%)
• Gaps: 78/489 - (15%)

  Fly    88 KLRYRRTQSVTRAEEISNKEEKQRRAQPGRPIHRPRDSLF--SWSSGFTNFSGLVNWGFLLLCIG 150
            |:..||:::..|..|:|                 |..|:|  ::.....:|:|.....::.:.|.
pombe    28 KIDLRRSRAAYRPLELS-----------------PTPSIFARNYQRNAVDFTGFFVLFWVAVSIM 75

  Fly   151 GLRLGLENLLKYGIRINPLDWFFFISGHNEGEGHNALILSIYSLVHISLCLAVEKGLA---MEII 212
            .....|||....|..:....:.:|.|        |.|.|:...|...|:.|     ||   .:|.
pombe    76 IFMSFLENFELTGRPVVGTIFKYFQS--------NLLDLAKADLAMSSMFL-----LAFPFQKIF 127

  Fly   213 AEG----LGLFIQIVNIVVLVCLPVVTIHLKGHAFSLMGASTVCFFYSVLFLKLWSYVQTNMWCR 273
            |.|    .||.:.:.:|::|:.|....:......:|....:.......|:.:||.||...|.|..
pombe   128 ALGYLRWYGLGVYLYSILILLFLSHCVLRCCLSNWSWTHRAMFILHSMVILMKLHSYNVVNGWYS 192

  Fly   274 QTYYQKNPRERRPSITLAELKKGVLNGGEEDEDVSKLVQ------------YPDNLTYKDLLYFL 326
            ..|:..|..:.:.:              :.|:|....|:            ||:|||..:.|.||
pombe   193 YCYHSLNKLQSKKT--------------DLDDDERSSVEFYEHCLNHHGNTYPENLTIPNALDFL 243

  Fly   327 CAPTLCYELNFPRTSRVRKRFLLKRLLEVVIGVNVVMALFQQWIIPSVRNSLIPFSNM-DVALAT 390
            ..|:|||:|.:|||:.||..:|::..|.....:.:::.:...:::|.:..::...... :.|.||
pombe   244 FMPSLCYQLYYPRTAHVRIHYLIECALGTFGCIFLLVIISDHFMVPVLAKAIRTIIEAPEDASAT 308

  Fly   391 ERLLKLA-------LPNHLCWLCFFYLMFHSFLNAVGELLNFADRNFYCDWWNANNIDTFWRTWN 448
            ...::|.       .|..|.:|..|:::|....|...|:..|||||||.||||....|.|.||||
pombe   309 YFAIRLGHTVAFLMFPFMLSFLLVFWVIFEGVCNFSAEITRFADRNFYDDWWNCWTWDQFARTWN 373

  Fly   449 MPVHRWCVRHLYIPVVQMGYSSRQAST-IVFLFSAVFHEYLVS-VPLQIYKIWAFMGMMGQIPLS 511
            .|||.:.:||:|:|:  ..:.|:..|| ..|..|:|.||.::. :.|:|.....|. .|.|||..
pombe   374 KPVHYFLLRHVYVPL--NSFMSKSLSTFFTFFVSSVLHELVMGCITLKIRGYGLFF-QMTQIPYI 435

  Fly   512 AISKSIEKKLGPRMGNIIVWASIILGQPLCIMAY 545
            .|.:....:....:|||..|.|||:|..|....|
pombe   436 IIQRQKFVRRHRLLGNIAFWFSIIIGIALIAALY 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mdy	NP_609813.1	MBOAT	115..545	CDD:445070	122/460 (27%)
are2	NP_588558.1	ARE1	1..472	CDD:227389	129/489 (26%)