Protein Alignment mys and itgb7

DIOPT Version :10

• Sequence 1: NP_524793.2
• Gene: mys / 44885
• FlyBaseID: FBgn0004657
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_021329800.2
• Gene: itgb7 / 797491
• ZFINID: ZDB-GENE-100728-2
• Length: 755
• Species: Danio rerio
• Alignment Length: 850
• Identity: 270/850 - (31%)
• Similarity: 422/850 - (49%)
• Gaps: 124/850 - (14%)

  Fly    13 LLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQTEGCAWCMQPDF--KGQS---RCYQN 72
            |:.:.:|....||     ...|.....|.::..|..||::.|||||.|.:|  .|:|   || .:
Zfish     6 LIALMVLLHCLGQ-----KYTLGEEPVCQNQPSCSECIRSPGCAWCTQMNFLKSGESNERRC-DS 64

  Fly    73 TSSL----CPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYS 133
            ..||    |.:....:|                              |.....|..::..|:
Zfish    65 PKSLKDRGCEDVRVINP------------------------------GKHPLDYVKNNDLSN--- 96

  Fly   134 QSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSME 198
                        :.|:   :||::||::.:.|||...:...:.:.:|:|||:|||||||||.||:
Zfish    97 ------------DSYN---VVQLKPQNVNIKLRVGVPYEFTVEFKRAQGYPIDLYYLMDLSYSMQ 146

  Fly   199 DDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCEN----CKAPYGYQ 259
            ||..::.|||.|:.:.:|.||....:||||||||.::||||.:|.:.::||.|    |:..:.:|
Zfish   147 DDLEQIKTLGQKILKKLKDITETVRIGFGSFVDKEMLPYVSQLPPRRKNPCPNRINTCQKAFMFQ 211

  Fly   260 NHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHY 324
            |.:||.::...|..||....:|||||:||.|.||||||..|:.:|.| ....|:||:::|..||.
Zfish   212 NVLPLTSDGREFEREVSKQNISGNLDSPEAGLDAIMQAAVCKDKIKW-GNVTRILVYTSDDTFHM 275

  Fly   325 AGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKL 389
            ||||:|||...|::|:||.:..|.|. ....||||:..:::.::||.|.:|||||......|:.|
Zfish   276 AGDGRLGGAFLPHNGQCHFNDMGSYI-GKAYDYPSVGHVSRVLQDNNIQLIFAVTEEIYPAYKAL 339

  Fly   390 VEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEM-KDNATGDVKITYFSSCLSN---GPEVQT 450
            ...|..|....|..||||||:|:.|.|..:||::.: ::.|..::.::|.|.|..|   ....:.
Zfish   340 SALIPQSVVGVLKKDSSNVVDLISEAYGNLSSTLVLEQEGAPAELMVSYRSKCKDNQAANEWREK 404

  Fly   451 SKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGY 515
            .:|..:|. ::::|..::....|.::|    |...|...||:|.::|.:...|.|.|   |:.
Zfish   405 GECQGIKH-EKITFQVRLNATACLKEP----QIFRIKMQGISEEVKITVDTECQCDC---GAA-- 459

  Fly   516 QVQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCG 580
            :..:..|:..|...||:|:||:.|.|..|.|...:.|.|..:  |||.::.|.. |||:|.|.||
Zfish   460 EKSSEHCNHKGDLSCGMCSCDEGYLGQNCSCVQQNDTIKMLD--SCRPNNRSLV-CSGQGSCECG 521

  Fly   581 ACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESND 645
            .|.|...      .|||:||||..|||:.....|:|  .|.||||:|:|:..:|||.|.|..|.|
Zfish   522 NCVCRNE------YSGKYCECDPDSCEKRNGVRCNG--KGKCECGKCECRDRYTGSACECSPSQD 578

  Fly   646 TCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELK 710
            .|....|  :|||.|.|.|..|.|.....|.:       |......|:..|||:.|.:..:|
Zfish   579 KCKNDWG--LCSGQGECVCNRCHCKPGVIGDY-------CSAFMDACELFKDCLACHLEGSG--- 631

  Fly   711 NGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSEQGELHV-YAQENKECPAK 774
               .|...|..      ..|:..|...|..|.:   ....:..:....||::| ||    :.|..
Zfish   632 ---SCHERCFN------ATVKHLEGTHELSCIY---KHVSYSVELKASGEVNVKYA----DLPHT 680

  Fly   775 VFMLGIVMG-VIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQATSTF 838
            |....:::| .::.|::.|:.|:::::||..::|.||:..|.|.:...:|...:||::|.||:|.
Zfish   681 VDKTAVIIGSSVSGIIITGIIIIIIYRLLLELYDYREYQSFVKMQNQTQWKEAQNPLFKGATTTV 745

  Fly   839 KNPMY 843
            .||::
Zfish   746 MNPLH 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mys	NP_524793.2	INB	45..505	CDD:197563	158/476 (33%)
		Integrin_B_tail	692..775	CDD:462325	18/83 (22%)
		Integrin_b_cyt	803..843	CDD:462580	14/39 (36%)
itgb7	XP_021329800.2	None